Testing of children

Ross LF, Moon MR. Ethical issues in genetic testing of children. Arch Pediatr Adolesc Med 2000 154 873-879. 

Extensive testing of children who reacted to certain foods has shown that if the food is powdered and put into a capsule that the child can t visually identify, there is often no antagonistic reaction. In other words, some food intolerances seem to have a psychosomatic side to them. This is true of many adults as well as children. The best thing to do is cut those foods out of the diet, no matter what is causing the intolerant person s symptoms. 

Versar, Inc. and Syracuse Research Corporation. 2010. Progress Report Development of Lead and Phthalate Standard Reference Materials for Use in Testing of Children s Products to Ensure CPSIA Compliance. Prepared for U.S. Consumer Products Safety Commission. Available from http //www.cpsc.gov/en/Research-Statistics/-Technical-Reports-/. Accessed... 

Immunological abnormalities were reported in 23 adults in Woburn, Massachusetts, who were exposed to contaminated well water and who were family members of children with leukemia (Byers et al. 1988). These immunological abnormalities, tested for 5 years after well closure, included persistent lymphocytosis, increased numbers of T-lymphocytes, and depressed helper suppressor T-cell ratio. Auto-antibodies, particularly anti-nuclear antibodies, were detected in 11 of 23 adults tested. This study is limited by the possible bias in identifying risk factors for immunological abnormalities in a small, nonpopulation-based group identified by leukemia types. Other limitations of this study are described in Section 2.2.2.8. A study of 356 residents of Tucson, Arizona, who were exposed to trichloroethylene (6-500 ppb) and other chemicals in well water drawn from the Santa Cmz aquifer found increased frequencies of 10 systemic lupus erythematosus symptoms, 5 (arthritis, Raynaud s phenomenon, malar rash, skin lesions related to sun exposure, seizure or convulsions) of which were statistically significant (Kilbum and Warshaw 1992). 

All apparently closed units from the 1-minute opening and closing test are then tested with children All packages that are opened in excess of 20% count against the SAUE (senior adult use effectiveness) Performance standard remains at 90% or greater... 

A neuropsychological evaluation of 148 of the Boston cohort children at age 10 years confirmed the continued presence of the association noted at 5 years of age (Bellinger et al. 1992). The primary end points evaluated were the WISC-R and the Kaufman Test of Educational Achievement (K-TEA). 

Bonithon-Kopp et al. (1986b) investigated another potential marker for lead exposure. Maternal and infant hair lead levels, determined from hair samples taken at birth, were found to be correlated inversely with results on neurobehavioral tests (McCarthy Scales of Children s Abilities) when the children were tested at 6 years of age. Other studies have also reported associations between hair lead levels and behavioral or cognitive test scores, but measures of lead in hair may not accurately reflect internal body burden of lead, and such data should not be used to evaluate internal dose-response relationships (EPA 1986a). 

In 1980 the Consumer Protection Act (15) required manufacturers to take reasonable steps to ensure that fabric -soft infill composites of domestic furniture resisted the cigarette test of BS5852 Part 1. These regulations did not apply to rouchings, trims to seat platforms etc. but only to the primary upholstery composites. The Consumer Protection Amendment of 1983 required specified children s furniture containing cellular materials had to resist Source 5 of BS 5852 Part 2. (16)... 

Heavy metals possess mutagenic effect. The assessment of mutagenic effect was assessed through evaluation of genes recessive mutation frequency in the micronucleus in oral mucous cells of children living at the tested areas (Tabl. 3). 

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