ETHYLENEDIAMINE Subject

The viscous oil resin Is slurried twice with 250 cc portions of methanol to remove any unreacted primary amines. The oil residue after being washed with methanol is dissolved in ethyl alcohol and 75 cc of concentrated hydrochloric acid is added dropwise to the warm alcohol solution of the base. The dihydrochloride salts of the several hydroabietyl ethylenediamines precipitates immediately from solution. The salt is then separated by filtering and is washed twice with 100 cc portions of cooled ethyl alcohol. The dihydrochloride salts of the dehy-droabietyl, dihydroabietyl and tetrahydroabietyl ethylenediamine mixture have a melting point of about 292°C to 295°C. On subjecting the mixture to solubility analyses it Is found that the dehydroabietyl ethylenediamine is present in substantially the same proportion as is the dehydroabietylamine in the original "Rosin Amine D."... 

Chelators, especially ethylenediamine tetra-acetic acid (EDTA), have been used as potentiators of the aetion of ehloroxylenol. Vaara has extensively reviewed the subject of permeabilization and Ayres, Furr and Russell have described a rapid method of evaluating the permeabilizahon of Ps. aeruginosa (see Further Reading, Sechon 6). 

Gianguzza and Orecchio [147] have carried out comparative trials of various methods for estimating nitrites in seawaters. These workers compared a method using sulfanilic acid/a-naphthylamine complexes with a method using sulfanilamide/N( 1-naphthyl) ethylenediamine complexes for the determination of nitrites in saline waters. The second method has the greater sensitivity and lower detection limits. The former method is subject to interference from chlorides, and this interference can be completely eliminated by the coupling diazotisation procedure of the latter method. 

The method is more sensitive than the biuret method and has an analytical range from 10 ju,g to 1.0 mg of protein. Using the method outlined below this is equivalent to sample concentrations of between 20 mg l-1 and 2.0 g l-1. The relationship between absorbance and protein concentration deviates from a straight line and a calibration curve is necessary. The method is also subject to interference from simple ions, such as potassium and magnesium, as well as by various organic compounds, such as Tris buffer and EDTA (ethylenediamine-tetraacetic acid). Phenolic compounds present in the sample will also react and this may be of particular significance in the analysis of plant extracts. 

The results suggest that the five-membered peptide chelate ring, in which the atoms are nearly coplanar, may be more subject to steric effects than is the case for the gauche conformation of chelate rings of ethylenediamine and its C-methyl derivatives. However, the corresponding nucleophilic displacement reactions have not been studied and it is too early to draw... 

CASRN 12427-38-2 molecular formula C4ff6MnN2S4 FW 265.31 Chemical/Physical. When soil containing maneb was subjected to a stream of moist air, carbon disulfide was formed. Carbon disulfide was also formed when maneb was suspended in a O.IM phosphate buffer at pff 7.0 and air was drawn through the system. The rate of carbon disulfide was higher at neutral and acidic solutions but lower under alkaline conditions. When the air was replaced by nitrogen, no carbon disulfide was evolved. Decomposition products in the reaction vessel identified by TLC were ethylene thiourea, ethylene thiuram monosulfide, elemental sulfur, and trace amounts of ethylenediamine (ffylin, 1973). 

For more information on this subject see individual explosives, eg, tri- and tetra-nitroaniline, ethylenediamine dinitrate, tetryl, etc... 

The phenomenon was observed for the first time by Brdicka [13] in the reduction of riboflavin and methylene blue studied by d.c. polaro-graphy. It did not receive much attention until it was rediscovered by several workers studying systems such as Tl+/Tl(Hg), Pb2+/Pb(Hg), and the more obvious system Co(III)—Co(II)—tris-ethylenediamine using impedance measurements [14—16]. The confusion that arose initially in the literature around this subject in the end led to the correct theoretical description [15, 17, 18], the general treatment remaining very complex [18,19]. 

This synthesis was carried out by reaction of polyethylene terephthalate and ethylenediamine in the presence of the metallic salts. Mechanical activation was supplied by vibratory milling in a nitrogen atmosphere. Granular polyethylene terephthalate (supplied by U.F.S.-Jassy) was subjected to mechanical processing in powdered form. It was purified by dissolving in a 40/60 phenol/chloroform mixture and reprecipitating with methanol. After filtration, the polymer was extracted... 

In addition, such a method of synthesis can be generated by making use of another destructive means for ligand synthesis. In that sense, the method was verified by achieving some polycondensation products of polyethylene terephthalate and ethylenediamine and their complexation with different metals by irradiating the system with cobalt-60 (gamma rays). These results also make up the subject of other studies. 

Classical methods for the synthesis of frans-dinitro-bis(ethylenediamine)cobalt(III) nitrate involve conversion of the cis isomer by heat1 or action of sodium nitrite on frans-chloronitrobis(othylenediamine)cobalt(III) nitrate.2 These methods involve isolation of intermediate coordination compounds and consequently are subject to low yields, based upon original cobalt(II) salt. The following procedure for the preparation of the trans compound gives an 84% yield it depends upon oxidation of cobalt(II) to cobalt(III) in the presence of sodium nitrite, ethylene-diamine, and nitric acid. 

Hydrated lanthanide salts may also be obtained by the addition of an excess of lanthanide oxide to a concentrated acid solution, heating at 80°C until the pH is between 5 and 6. The residual oxide is removed by filtration, and the filtrate is subjected to rotary evaporation. This procedure may lead to the presence of oxo and hydroxy species in solution. At present hydrated lanthanide salts of 99.9% purity are available commercially. Salts of the highest purity are generally used in spectroscopic and magnetic studies. The purity of lanthanide salts can be determined by complexometric titration with ethylenediamine tetraacetic acid [1]. 

Ethylenediamine (en), diethylenetriamine (dien), triethylene-tetramine (trien), and tetraethylenepentamine (tetren) form well characterized complexes with M(ii) ions. Such complexes have been the subjects of a number of NMR exchange studies. (299-303) studies have established the identities of [Cu(en)(H20)4], [Cu(en)2-(HjOjj], and complexes involving both en and sulphosalicylic acid ligands. (299-301) NMR studies have been made on aqueous solutions of [Ni(dien)(H20)3], [Ni(tren)(H20)2], and... 

Conformation of Ethylenediamine. Whether the ethylenediamine chelate ring is completely planar or puckered has also been a subject of controversy. The conformation of ethylenediamine may be cis if planar and gauche if puckered. Infrared studies have proved to be very useful in distinguishing cis, trans, and gauche conformation of 1,2-substituted... 

The mononuclear cations of chromium(III) and cobalt(lll) of the tetraammine and the bis(ethylenediamine) series belong to a class of complexes that has been most extensively studied. The present complexes will often prove useful as starting materials for preparing complexes within their class, and reactions with these complexes are likely to form the subject of many future investigations. 

Several other amines have been used to make penicillin salts, and research is continuing on this subject. Other amines that have been used include 2-chloroprocaine L-A/-methyl-l.2-diphenyl-2-hydroxyethylamine (L-ephenamine) diben-zylamine tripelennamine (Pyribenzamine) and A/.A/ -bis-(dehydroabietyl)ethylenediamine (hydiabomine). 

The first reports of a reaction of an amine with an aldehyde by Schiff [584] led to the establishment of a large class of ligands called Schiff bases. Among the most important of the Schiff bases are the tetradentate salen ligands (N,N -bis(salicy-laldehydo)ethylenediamine), which were studied extensively by Kochi and coworkers, who observed their high potential in chemoselective catalytic epoxidation reactions [585]. The best known method to epoxidize unfunctionalized olefins enantioselectively is the Jacobsen-Katsuki epoxidation reported independently by these researchers in 1990 [220,221]. In this method [515,586-589], optically active Mn salen) compounds are used as catalysts, with usually PhlO or NaOCl as the terminal oxygen sources, and with a O=Mn (salen) species as the active [590,591] oxidant [586-594]. Despite the undisputed synthetic value of this method, the mechanism by which the reaction occurs is still the subject of considerable research [514,586,591]. The subject has been covered in a recent extensive review [595], which also discusses the less-studied Cr (salen) complexes, which can display different, and thus useful selectivity [596]. Computational and H NMR studies have related observed epoxide enantioselectivities... 

One more class of thallium(III) compounds has been subjected to structural investigations, namely the compounds of the type TKpoly-dentate ligandlX, where the polydentate ligands were EDTA (ethylene-diaminetetraacetate), DTPA (diethylenetriaminepentaacetate), TPEN (tetrakis-(2-pyridylmethyl)-ethylenediamine), NTA (nitrilotriacetate), bipy (bipyridine), terpy (2,2" 6, 2 terpyridine), pent-en (N,N,N, N -tet-rakis-(2-aminoethyl)-ethylenediamine), andX = OH, H2O, CN", N03 (106, 109, 94). In these compounds, thallium(III) is usually hepta- or even octa-coordinated, in contrast to monodentate ligands, where the... 

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