Start checklists

The following sections describe, in general terms, the requirements of the automotive industry for each of the critical performance metrics. Vehicle requirements will of course change from model to model and from year to year, so functional specifics, such as battery sizes or power, are not appropriate here. This list, however, should provide a starting checklist for anyone contemplating a particular battery for any of the header applications. 

Table 3,3.1 -1 (DOE, 1996) suggests main headings for a checklist. These are global heading starting with the process description,...

The following checklist maybe useful in organizing your thinking. You can complete it formally, in writing, or simply conceptually or mentally what s important is to think these kinds of questions through in advance of starting up a team effort. 

Skill-based Errors manual variability strong but wrong action sequences Train for physical and manipulative skills (repeated practice and feedback) Checklists setting out starting and finishing activities and checks Layout and labeling of controls and process lines Distinguish tetween plant areas with similar appearance but different functions Provide feedback... 

The first question is a request to the manufacturer and the second results in a checklist for the start in the laboratory. The following lists contain recommendations, but they cannot comprise all possibilities and not all points are always necessary. The order of points is more according to technical reasons, it does not represent the importance. 

Preparation of a field checklist to inspect critical items prior to start-up... 

Table 3.4 presents a list of hazards commonly found in process operations, grouped according to how energy is stored. It can be used as a starting point to develop a checklist... 

In addition, the reviewers recommended the following (1) Hang phosgene indicator paper around the hood, room, and operating areas (this paper is normally white but turns brown when exposed to 0.1 ppm of phosgene), (2) use a safety checklist, daily, before the process is started, and (3) post an up-to-date process sketch near the process. 

Start-up start-up and test-run documents data on process performance first operation experience What-If, Checklist... 

Loss-of-Containment Causes The list in Table 23-30 indicates four basic ways in which containment can be lost. These cause cate-ories can be used both as a checklist of considerations during the esign process and as a starting point for evaluating the adequacy of safeguards as part of a process hazard and risk analysis. 

A variety of public and proprietary checklists are available that vary in comprehensiveness. There is no reason for an organization to start from scratch in developing a checklist. A human factors checklist and tables are included in Chapter 6. The Systematic Cause Analysis Technique (SCAT)< > is an example of a proprietary checklist. The accompanying CD-ROM also contains examples of checklists which can be modified for the readers use. 

The protocol should specify what should be recorded directly into the CRF and what will also be recorded in the medical records. The CRF will contain all the pertinent data associated specifically with the clinical trial but some will be repeated in the medical records, for example, the protocol identification number, date of consent, date of commencement of the study, key baseline medical findings, visit dates, start and finish dates of the study drug/placebo or treatment, concurrent medication, adverse events and key efficacy and any unscheduled or scheduled actions or interventions (such as escape medication). Additional information obtained from biopsy reports, radiographs and similar documents will provide confirmation that the data in the CRF are recorded correctly. Monitors, QA auditors and inspectors need to see all the medical records available to the investigator. It is not appropriate to create copies of data from CRFs or checklists derived from medical records and claim that these are source documents. 

Experienced senior staff of the sponsor must always visit the investigator site before a new clinical trial starts, even if the investigator has been involved in previous studies. Most pharmaceutical companies have checklists and SOPs of the requirements of an investigator site. Key questions will need to be answered relating to staff support and the present workload of the site. The competence of the staff to conduct any procedures, the maintenance, calibration and QC of any equipment to be used, and whether other clinical trials demand too much resource are aU questions that need answers. In addition, the facilities should be inspected to establish whether the site could store and securely archive the large amounts of documents and study drugs that will be present. The pharmacy may play a major role in the study and therefore the facility and the pharmacist should be visited. 

In this chapter, we ask you to look again at your written work, but this time as an entire document. Rather than write and rewrite section by section, we ask you to take a step back and reflect on your work as a whole. The goal is to achieve a coherent and fluent piece of writing that reads well from start to hnish. To facilitate this process, we have created a checklist of nine items (listed below). We present each item and ask you to review your entire work from the perspective of this item, making changes and improvements as needed. As you become familiar with these items, you will become a better and more efficient editor of your own written work, a necessary prerequisite for becoming an effective writer. 

QAI will monitor the results of pressure differentials, temperature, and humidity obtained from the control room daily before starting the manufacturing process in the area for comparison of results with the standard provided for each area. They should be within limits. Whenever any operation such as manufacturing or filling starts, QAI will fill an inspection start-up checklist and give release for manufacturing or packaging. See attachment no. 1700.30(A), 1700.30(B), and 1700.30(C). 

The most important factors for the entire process of equipment qualification and computer system validation in analytical laboratories are proper planning, execution of qualification according to the plan, and documentation of the results. The process should start with the definition of the analytical technique and the development of user requirement and functional specifications. For computer systems, a formal vendor assessment should be made. This can be done through checklists and vendor documentation with internal and/or external references. For very complex systems, it should go through a vendor audit. 

To help the reader identify the activity associated with each aspect on the more intuitive level, checklists are presented. They are not comprehensive, but can help the beginning experimenter get started. We have placed them at the beginning of Part B to give an overview of the information necessary for successful experimentation. Each reader will spend more or less time initially reading through the checklists. They can be returned to when the practical work is in the planning phase. It is important to use them critically, checking which points apply to the situation at hand and to modify and add appropriate points that have been missed. 

Continual monitoring of equipment and plant is standard practice in chemical process plants. Equipment deteriorates and operating conditions may change. Repairs sometimes are made with improvements whose ultimate effects on the operation may not be taken into account. During start-up and shut-down, stream compositions and operating conditions are much different from those under normal operation, and their possible effect on safety must be taken into account. Sample checklists of safety questions for these periods are in Table 1.7. 

TABLE 1.7. Safety Checklist of Questions About Start-up and Shut-down... 

A series of hardware, instrument, and procedure changes were recommended and accepted to eliminate any repeat performances. One of the ways similar incidents can be reduced without resorting to more hardware or software is the religious use of simple checklists that require initials and the time each step in the start-up or shutdown process was completed. 

Of the three methods, the first, or checklist technique, has the greatest tendency to make patients introspective regarding their symptoms. Not surprisingly, this approach elicits the largest number of adverse reaction reports. Regardless of the method used, however, it is imperative that the questions be applied in the same way at each patient assessment, preferably by the same person, for the duration of the study. It is also recommended that patients be carefully questioned prior to administration of the study drug. It is remarkable how many so-called adverse reactions are, in fact, symptoms of other conditions present before the study treatment starts. 

The following essential checklist is used to start a shelter operation ... 

If the answer to any of these questions is no, then the actions and responsibilities to be taken to resolve the deficiencies should be recorded and verified as complete. The contract should not start nntil any deficiencies are nnderstood and corrected. If a checklist is nsed, it shonld be annotated with answers to the qnestions and signed as complete by the contract reviewer (who may well be the qnality manager) and contract manager (who may well be the project manager). In this simple... 

Typically, the validation evidence for a SCADA system is created and approved through system development. Large systems are often formed of smaller subsystems and integrated during development and start-up efforts. Care should be taken to avoid using checklists as a substimte for validation deliverables or quality assurance reviews checklists simply indicate the presence or absence of required validation products. 

On the day of the test. Intramuscular Injections were given at 9 a.m., and the exercise was started Immediately. It ended at 4 p.m. A battery of tests (heart rate, blood pressure, rectal temperature. Number Facility Test, and behavioral checklist) was administered to each volunteer at 9 30, 10, and 11 a.m., noon, and 1 and 4 p.m. The performance of volunteers on this day was graded by the same Judges who had been present on the control day. 

If you use the steps in Table 2.4 as a mental checklist each time you start to work on a problem, you will have achieved the major objective of this chapter and substantially added to your professional skills. These steps do not have to be carried out in the order prescribed, and you may repeat steps as the issues in the problem become clearer. But they are all essential. 

Table 1 presents a checklist for troubleshooting distillation columns. Hopefully it can be used as a starting point for a specific unit. The order will depend on which process variables are most important. Again, the simple checks, which can be made quickly, should be done first,... 

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