Sodium Lactate Solution

Treatment of metabolic acidosis usually involves intravenous sodium lactate solution to normalize blood pH the cause of the lactic acid overproduction should be determined and treated. 

Sodium Lactate Solution occurs as a clear, colorless or practically colorless, slightly viscous liquid that is odorless or has a slight, not unpleasant odor. It is miscible with water. It is normally available in solutions with concentrations ranging from 60% to about 80%, by weight. 

Sodium lactate solution Buffer agent, isotonicity, pH adjustment, stabilizer iv... 

BP Sodium lactate solution PhEur Natrii lactatis solutio USP Sodium lactate solution... 

The PhEur 2005 and USP 28 describe sodium lactate solution as a mixture of the enantiomers of sodium 2-hydroxypropano-ate in approximately equal proportions. 

Fifteen samples were treated with 5 ml of a sodium lactate solution (1.5% p/v in water). 

Chemical Salt Splitting of a Lactate Salt. Lactate salts can be split with the help of auxiliary chemicals and the regeneration of these chemicals. A patent by Baniel et al., for example, describes a method in which a sodium lactate solution is acidified with CO2 under pressure, and simultaneously undissociated lactic acid is extracted and insoluble sodium bicarbonate (NaHCOs) is formed [65]. 

If acidaemia is itself life-threatening to a patient, an intravenous infusion of sodium bicarbonate or sodium lactate solution may be given. If the urgency is not so great, a sodium citrate and citric acid mixture by mouth may be given. 

The purified commercial di-n-butyl d-tartrate, m.p. 22°, may be used. It may be prepared by using the procedure described under i o-propyl lactate (Section 111,102). Place a mixture of 75 g. of d-tartaric acid, 10 g. of Zeo-Karb 225/H, 110 g. (136 ml.) of redistilled n-butyl alcohol and 150 ml. of sodium-dried benzene in a 1-litre three-necked flask equipped with a mercury-sealed stirrer, a double surface condenser and an automatic water separator (see Fig. Ill, 126,1). Reflux the mixture with stirring for 10 hours about 21 ml. of water collect in the water separator. FUter off the ion-exchange resin at the pump and wash it with two 30-40 ml. portions of hot benzene. Wash the combined filtrate and washings with two 75 ml. portions of saturated sodium bicarbonate solution, followed by lOu ml. of water, and dry over anhydrous magnesium sulphate. Remove the benzene by distillation under reduced pressure (water pump) and finally distil the residue. Collect the di-n-butyl d-tartrate at 150°/1 5 mm. The yield is 90 g. 

Notice in Example 141(a) that the total volume of solution is irrelevant All that is required to solve for [H+] is the number of moles of lactic acid and sodium lactate. The pH of the buffer is 3.85 whether the volume of solution is 550 mL, 1 L, or even 10 L. This explains why diluting a buffer with water does not change the pH. 

A solution of equal concentrations of lactic acid and sodium lactate was found to have pH = 3.08. (a) What are the values of pK, and K, of lactic acid (b) What would the pH be if the acid had twice the concentration of the salt ... 

Injection 50 mg calcium glycerophosphate and 50 mg calcium lactate per 10 ml in sodium chloride solution (0.08 mEq Ca/mL) (Rx) Calphosan (Glenwood)... 

A solution of equal concentrations of lactic acid and sodium lactate was found to have pH = 3.08. 

The performance of the ED recovery of sodium lactate from model solutions was mathematically described by several authors (Boniardi et al., 1996 Fidaleo and Moresi, 2004 Yen and Cheryan, 1993). It was found that the permeation flux of lactate was independent of the presence of lactose and glucose in culture medium and that the fluxes of both sugars were practically negligible (Yen and Cheryan, 1993). By using the performance indicators reported in Table XV, Moresi and Sappino (2000) estimated that the ED recovery of sodium lactate was less expensive than that of disodium itaconate or trisodium citrate. 

The effective solute (ts) transport number, ranged from 93% to 98%, even if reduced to 88% for sodium lactate. The water transport number (tw) increased from 9.3 to 15.6 and correspondently the maximum salt weight concentration in the concentrated stream (CBc,max) ranged from 286 to 350 kg/m3. Finally, while the surface resistance (rc) of the cation-exchange membranes was found to be about constant (5 2fl cm2), ra tended to increase with A/b. However, the specific electric energy consumption (e) slightly increased from 0.19 to 0.22 kWh/kg of salt recovered. 

What is the pH of a solution that is equal parts sodium lactate and lactic acid ... 

Back extraction with a strong alkaline (NaOH) solution is an irreversible reaction that simultaneously regenerates the amine and produces sodium lactate and water ... 

Perform a blank determination (see General Provisions), and make any necessary correction. Each milliliter of 0.1 A perchloric acid is equivalent to 11.21 mg of C3H5Na03. Chloride Determine as directed in the Chloride Limit Test under Chloride and Sulfate Limit Tests, Appendix IIIB. Any turbidity produced by a quantity of a sample solution containing the equivalent of 40 mg of sodium lactate does not exceed that shown in a control containing 20 pg of chloride (Cl) ion. 

Sample Solution Transfer a quantity of sample, equivalent to 20.0 g of sodium lactate and accurately weighed, into a 100-mL volumetric flask, dilute to volume with water, and mix. 

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