Iso-Propyl lactate

M-Butyl formate. Ethyl iso-butyrate IsO -butyl acetate Ethyl butyrate -Propyl propionate Iso-amyl formate, -But> l acetate Iso-propyl butyrate Iso-butyl propionate n-Propyl -butyrate -Butyl propionate Iso-butyl isobutyrate Ethyl lactate Iso-butyl butyrate Cycloheicyl formate -Butyl -butyrate Iso-propyl lactate. Cyclohexyl acetate Diethyl oxalate Di-iao-propyl oxalate... 

The purified commercial di-n-butyl <2-tartrate, m.p. 22% may be used. It may be prepaid by using the procedure described under iso-propyl lactate (Section 111,102). Place a mixture of 75 g. of d-tartaric acid, 10 g. of Zeo-Karb 225/H, 110 g. (136 ml.) of redistilled n-butyl alcohol and 150 ml. of sodium-dried benzene in a 1-litre three-necked fiask equipped with a mercury-sealed stirrer, a double svu-face condenser and an automatic water separator (see Fig. Ill, 726,1). Refiux the mixture with stirring for 10 hours about 21 ml. of water collect in the water separator. Filter off the ion-exchange resin at the pump and wash it with two 30-40 ml. portions of hot benzene. Wash the combined filtrate and washings with two 75 ml. portions of saturated sodium bicarbonate solution, followed by lOo ml. of water, and dry over anhydrous magnesium sulphate. Remove the benzene by distillation under reduced pressure (water pump) and finally distil the residue. Collect the di-n-butyl d-tartrate at 150°/l-5 mm. The yield is 90 g. 

Lactic acid wo- Propyl alcohol iso-Propyl lactate... 

Propyl bromide, 13, 27 iio-Propylbromomalonic acid, 11, 27 T-Propylene glycol, 10, 84 -Propyl iodide, IS, 62 iso-PROPYL lactate, 10, 88 iso-PROPYL THIOCYANATE, 11, 92 Pseudodurene, 10,37 Pyridine, 11, s 12, 20 Pyeomelutic ACID, 10, 90 Pyrrole, 10,113 Pyruvic acid, 10, 114... 

Successful results have been obtained (Renfrew and Chaney, 1946) with ethyl formate methyl, ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, sec.-butyl and iso-amyl acetat ethyleneglycol diacetate ethyl monochloro- and trichloro-acetates methyl, n-propyl, n-octyl and n-dodecyl propionates ethyl butyrate n-butyl and n-amyl valerates ethyl laurate ethyl lactate ethyl acetoacetate diethyl carbonate dimethyl and diethyl oxalates diethyl malonate diethyl adipate di-n-butyl tartrate ethyl phenylacetate methyl and ethyl benzoates methyl and ethyl salicylates diethyl and di-n-butyl phthalates. The method fails for vinyl acetate, ieri.-butyl acetate, n-octadecyl propionate, ethyl and >i-butyl stearate, phenyl, benzyl- and guaicol-acetate, methyl and ethyl cinnamate, diethyl sulphate and ethyl p-aminobenzoate. 

Jso-propyl lactate has been prepared by heating iso-propyl alcohol and lactic acid in a sealed tube at 1700,1 2 and from silver lactate and iso-propyl iodide, together with the iso-propyl ester of a-iso-propoxy-propionic acid.3 Direct esterification of the acid with the alcohol, with sulfuric acid, has failed to give a yield greater than 20 per cent of the theoretical amount, and the product has been less pure. 

Propyl bromide, 13,21 15, 72 im-Piopylbiomomalonic acid, 11, 21 /-Propylene glycol, 10,84 -Propyl iodide, 13, 62 mo-Propyl lactate, 10,88 ti-Propyl phosphate, 16,10 tt-Piopyl sulfate, 19, 27 -Propyl sulfide, 15, 72 -Propyl sulfite, 19,30 isO-PROPYX THIOCYANATE, 11, 92 ixo-Propyl- t-toluidine, 18, 42 fj-Piopyl- -toluidine, 18, 42 Protocatechualdehyde, 18, 76 Pseudodurene, 10, 37... 

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