Calcium lactate

Calcium lactate (CH3-CH(OH)-COO)2Ca 5H2O) is produced as an intermediate in the production of lactic acid by the reaction of slaked lime with raw lactic acid. It acts as a protein plasticiser (coagulant) and is used as an egg extender and foaming agent. It is also used in pharmaceuticals as a source of calcium [31.17], and as a buffer and source of calcium in bread. Its production requires food-grade slaked lime (e.g., [31.30] and Table 31.2). 

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If ingestion occurs, dilute solutions of calcium compounds (calcium lactate, calcium gluconate, etc) or a large amount of milk followed by magnesium sulfate should be adrninistered (63,64). 

Salts of Organic Acids. Calcium salts of organic acids may be prepared by reaction of the carbonate hydroxide and the organic acid (9). Calcium lactate [814-80-2] is an iatermediate ia the purification of lactic acid from fermentation of molasses. Calcium soaps, soaps of fatty acids, ate soluble ia hydrocarbons, and are useful as waterproofing agents and constituents of greases (9). 

Calcium lactate (5H2O) [814-80-2] M 308.3, m anhydr at 120°. Crystd from warm water (lOmL/g) by cooling to 0°. 

Calcistin (Hestia)-comb. with calcium lactate wfm Creme domistan vit. F (Servier) wfm. 

Because swelling and consequent bulk erosion induced by the water-soluble salt is not desirable, use of the low-water-solubility, sUghtly acidic salt calcium lactate was investigated (30). By using this excipient it was hoped that a lowering of the pH within the surface layers of the device would take place and release of the drug would be controlled by polymer erosion confined to the surface layers of the device. In these experiments norethindrone was replaced by the currently favored steroid levonorgestrel. 

FIGURE 17 Scanning electron micrograph (30x) of polymer rods (2.4 X 20 mm prepared from 3,9-bis(ethylidene-2,4,8,10-tetraoxaspiro-[5,5]undecane) and a 70 30 mole ratio of trans-cyclohexane dimethanol and 1,6-hexanediol after 10 weeks in rabbit. Rods contain 30 wt% levonorgestrel and 2 wt% calcium lactate. (From Ref. 30.)... 

Lactic acid Lactobacillus delbrueckii Rhizopus oryzae Calcium lactate is a convenient source of Ca for oral administration constituent of intraperitoneal dialysis solutions... 

Tuba et al. (24) reported that rats fed 15.4% dried rhubarb or an equivalent amount of sodium oxalate grew at a slower rate and had higher serum alkaline phosphatase levels than rats fed control diets containing calcium lactate. The calcium lactate diets contained either 0.5% or 0.09% calcium. The rhubarb and sodium oxalate diets contained 0.5% calcium and 0.95% oxalate. 

Calcium Lactate Dissolve 0.5 g in DW add 2 ml of a 20% w/v soln. of iron-free-citric acid and 0.1 ml of thioglycollic acid, mix, make alkaline with iron-free-ammo-nia soln., dilute to 50 ml with DW and allow to stand for 5 minutes. Any colour produced is not more intense than that obtained by treating in the same manner 2.0 ml of iron standard solution (20 ppm Fe) in place of the soln. being examined. 

Calcium Lactate Dissolve 1.0 g in DW by the addition of 2 ml of HC1. Perform the test with the solution. Complies with the limit test for sulphates. 

How will you determine the limit test for Iron in Calcium Lactate and Zinc Oxide Explain. 

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