Sodium bisulfite test

So now we have this solvent containing ketone, dried with MgS04... Not being able to vac-distill today, took about 50 mis of solvent/ketone and placed in beaker on stir plate and boiled off the solvent. The resulting oil was a nice reddish-orange color. Had a very unique smell too. Took about 2 grams worth of this ail, added to a test tube containing a saturated solution of sodium bisulfite... In less than 60 seconds the oil precipitated into a whitish yellow mass (very similar to what acetone would do if added to a bisulfite solution). Never had this quick of a crystallization. Not... 

The fermentation-derived food-grade product is sold in 50, 80, and 88% concentrations the other grades are available in 50 and 88% concentrations. The food-grade product meets the Vood Chemicals Codex III and the pharmaceutical grade meets the FCC and the United States Pharmacopoeia XK specifications (7). Other lactic acid derivatives such as salts and esters are also available in weU-estabhshed product specifications. Standard analytical methods such as titration and Hquid chromatography can be used to determine lactic acid, and other gravimetric and specific tests are used to detect impurities for the product specifications. A standard titration method neutralizes the acid with sodium hydroxide and then back-titrates the acid. An older standard quantitative method for determination of lactic acid was based on oxidation by potassium permanganate to acetaldehyde, which is absorbed in sodium bisulfite and titrated iodometricaHy. 

Health and Safety Factors. Sodium metabisulfite is nonflammable, but when strongly heated it releases sulfur dioxide. The oral acute toxicity is slight and the LD q (rat, oral) is 2 g/kg. Sodium bisulfite appears to be weakly mutagenic to some bacteria, ia rodent embryos, and ia a human lymphocyte test. There is iaadequate evidence for carciaogenicity (183,343). 

There are several comprehensive reviews of analytical methods for vitamin K (19,20). Owiag to the preseace of a aaphthoquiaoae aucleus, the majority of analytical methods use this stmctural feature as a basis for analysis. Several identity tests such as its reaction with sodium bisulfite or its uv spectmm exploit this characteristic. Although not specific, titrimetric, polarographic, and potentiometric methods have also been used (20). 

It is advisable to test the solution after the addition of the sodium bisulfite with acidified potassium iodide solution to be sure that all the hypochlorite has been destroyed. If... 

The anticonvulsant activity of some 1,3-benzisoxazoles was discovered in routine testing. One of the more interesting of the subsequent analogues prepared was zonisamide (39). One of its syntheses starts with l,2-benzisoxazole-3-acetic acid (36) which is brominated and subsequently decarboxylated to give 37. Displacement of halogen in 37 with sodium bisulfite interestingly... 

Benzaldehyde. There are many ways to make many types of benzaldehydes. Different benzal-dehydes give different products. I am giving the formula to the basic type. It can be modified to give a specific type of benzaldehyde. 50 g of benzyl chloride and 50 g of copper nitrate in 300 cc of water are refluxed together, in a current of carbon dioxide for 8Vi hours or until a sample tested contains very little chlorine. Extract the mixture with ether, remove the ether on a water bath, and stir or shake the remaining oil for 1 hour (shaking is best) with a saturated solution of sodium bisulfite. Let stand for 2 hours, filter with vacuo and wash with a little cold alcohol, then with cold ether. The washings are warmed with an excess of 10% sulfuric acid. The aldehyde... 

The following alternative procedure may be used to prepare a solution of disodium hydroxylaminedisulfonate. Sodium nitrite (15 g., 0.217 mole) and 41.6 g. (0.40 mole) of sodium bisulfite are added to 250 g. of ice. With stirring, 22.5 ml. (0.40 mole) of acetic acid is added all at once and the mixture is stirred for 90 minutes in an ice hath. At the end of the stirring period the reaction solution is pH 5 and a potassium iodide-starch test is negative. A solution of 50 g. (0.47 mole) of sodium carbonate in water (total volume 250 ml.) is added. This buffered solution of disodium hydroxylaminedisulfonate may be used for electrolytic oxidation. 

It is more convenient to prepare cuprous chloride by reducing copper sulfate with sodium bisulfite than by the action of copper upon cupric chloride (see also p. 33). It is well to test a sample of the filtrate with sodium bisulfite solution no further cuprous chloride should separate. 

Instruct others to maintain a safe distance. Wear breathing apparatus, eye protection, laboratory coat, and nitrile rubber gloves. Cover the spill with a 1 1 1 mixture by weight of sodium carbonate or calcium carbonate, clay cat litter (bentonite), and sand. When the bromine has been absorbed, quickly scoop into a plastic pail and, in the fume hood, very slowly add the mixture to a pail of cold water. Add 10% sodium bisulfite until solution turns colorless. Test the pH and neutralize if necessary with sodium carbonate. Decant the solution to the drain. Treat the solid residue as normal refuse. Wash the spill area thoroughly with soap and water.20... 

Wear a face shield, goggles, butyl rubber gloves, and a laboratory coat. In the fume hood behind a shield, slowly add the peracetic acid to a large volume of ice-cold, saturated sodium bisulfite solution. Test a drop of the solution with starch-iodide paper. If a blue color is produced, add more saturated sodium bisulfite solution. Neutralize the solution with 5% aqueous hydrochloric acid or with sodium carbonate as appropriate. Wash into the drain.7... 

Wear eye protection, laboratory coat, and nitrile rubber gloves. Scoop into a pail of water. In the fume hood, slowly add a freshly prepared 10% solution of sodium bisulfite or sodium metabisulfite (50 mL/g or 75 mL/g, respectively). Test for presence of nitrite using starch-iodide paper dipped in dilute acetic acid.7 When nitrite is completely destroyed, decant the liquid to the drain.6 Spill site should be washed thoroughly with water to remove all oxidant, which is liable to render any organic matter (e.g., wood, paper, textiles) dangerously combustible when dry. Clothing wetted with the solution should be removed and washed immediately.2... 

Wear eye protection, laboratory coat, and nitrile rubber gloves. Prepare a 10% aqueous solution of the waste sodium chlorate. For each 10 mL of solution, slowly, and while stirring, add 44 mL of a 10% solution of sodium bisulfite (this allows about 50% excess of reducing agent). The continued presence of chlorate can be detected by adding, to 3 mL of the solution, a freshly prepared solution of potassium iodide (100 mg) in 3 mL of 3 M sulfuric acid (prepared by cautiously adding 0.5 mL of concentrated acid to 2.5 mL of cold water). An amber to brown color indicates the presence of chlorate. Add sodium bisulfite solution until the test is negative. Neutralize the acidic solution with sodium carbonate and discard into the drain with at least 50 times its volume of water.11 12... 

Dampen the stains with a 5% solution of potassium permanganate. Allow to set for a few minutes and then apply a 10% solution of sodium bisulfite. Care should be taken with colored fabrics, as the area may become bleached. Test on an out-of-the-way area, such as a shirttail. 

Lead Determine as directed for Method I in the Atomic Absorption Spectrophotometric Graphite Furnace Method under Lead Limit Test, Appendix IIIB, using a 10-g sample. Methanol Transfer 1 drop of sample to a test tube, add 1 drop of 1 20 phosphoric acid and 1 drop of 1 20 potassium permanganate solution mix and allow to stand for 1 min. Add, dropwise, 1 10 sodium bisulfite solution until the permanganate color disappears. If a brown color remains, add 1 drop of the phosphoric acid solution. Add 5 mL of freshly prepared chromotropic acid TS to the colorless solution, and heat it in a water bath at 60° for 10 min. No violet color appears. 

A new plant requires a large rotary vacuum filter for the filtration of zinc sulfite from a slurry containing 1 kg of zinc sulfite solid per 20 kg of liquid. The liquid contains water, sodium sulfite, and sodium bisulfite. The filter must handle 8000 kg of slurry per hour. What additional information is necessary to design the rotary vacuum filter How much of this information could be obtained from laboratory or pilot-plant tests Outline the method for converting the test results to the conditions applicable in the final design. 

---