Sodium bisulfite, reaction with

There are several comprehensive reviews of analytical methods for vitamin K (19,20). Owiag to the preseace of a aaphthoquiaoae aucleus, the majority of analytical methods use this stmctural feature as a basis for analysis. Several identity tests such as its reaction with sodium bisulfite or its uv spectmm exploit this characteristic. Although not specific, titrimetric, polarographic, and potentiometric methods have also been used (20). 

D Acid. Dissolve the 2,4-D (1 g) as far as possible in 200 mL of 10% sodium hydroxide solution then add 14 g of potassium permanganate and stir the mixture at room temperature for 24 hours. Reduce any excess permanganate remaining at the end of the reaction with sodium bisulfite, and neutralize the solution with dilute hydrochloric acid (1 volume of concentrated acid added to 5 times its volume of water). Pour the solution into the drain and discard any residual brown manganese dioxide with regular refuse. 

Diels-Alder reactions, 133, 135 epoxidation, 69-72, 516 grafting on polyethylene, 462 hydroformylation, 44 hydrogenation, 41, 42 isomerization catalysts, 133, 484 isomerization during polymerizations, 484 isomerization kinetics, 484 isopropyl alcohol radical reaction, 207 MA copolymerization, 532, 534, 541 Michael reactions, 63-66 nitrone adducts, 224, 225 olefin copolymerization, 288 olefin ene reactions, 162 phenanthrene adducts, 181 plasticizers use, 14 production—synthesis, 14, 78-81 radical copolymerization, 270, 275-277, 307, 315, 317, 333, 345, 365, 379 radical polymerization, 239, 264, 287 reaction with allyl alcohol, 46 reaction with sodium bisulfite, 53 styrene copolymerization, 365, 483 tetraalkyl methylenediphosphonate adduct, 66 transesterification, 46 /7-xylylene copolymerization, 359 dialkyl stannyl, PVC stabilizer, 275 diaryl, synthesis from MA, 80 pyridinium, betaine intermediate, 216... 

The reaction with sodium sulfite or bisulfite (5,11) to yield sodium-P-sulfopropionamide [19298-89-6] (C3H7N04S-Na) is very useful since it can be used as a scavenger for acrylamide monomer. The reaction proceeds very rapidly even at room temperature, and the product has low toxicity. Reactions with phosphines and phosphine oxides have been studied (12), and the products are potentially useful because of thek fire retardant properties. Reactions with sulfide and dithiocarbamates proceed readily but have no appHcations (5). However, the reaction with mercaptide ions has been used for analytical purposes (13)). Water reacts with the amide group (5) to form hydrolysis products, and other hydroxy compounds, such as alcohols and phenols, react readily to form ether compounds. Primary aUphatic alcohols are the most reactive and the reactions are compHcated by partial hydrolysis of the amide groups by any water present. 

A.lkyl Sulfosuccinate Half Asters. These detergents are prepared by reaction of maleic anhydride and a primary fatty alcohol, followed by sulfonation with sodium bisulfite. A typical member of this group is disodium lauryl sulfosucciaate [26838-05-1]. Although not known as effective foamers, these surfactants can boost foams and act as stabilizers when used ia combination with other anionic surfactants. In combination with alkyl sulfates, they are said to reduce the irritation effects of the latter (6). 

By the nitrosation of 2-naphthalenol and the reaction of the nitroso compound with sodium bisulfite. By nitrosation/reduction of 6-hydroxy-2-naphthalenesulfonic acid. 

Sodium P-chloroethanesulfonate [15484-44-3] can be obtained by reacting vinyl chloride with sodium bisulfite [7631-90-5] (66). Reaction with nitronium tetrafluoroborate [13826-86-3] yi ds l-chloro-l- uoro-2-nitroethane [461-70-1] (67). 

Bisulfite Reaction. Coumarin combines readily with sodium bisulfite solutions to form soluble sodium 3- or 4-hydrosulfonates (23). Coumarin can be regenerated by acidification and this method has been used for its purification. 

The action of sulfur nucleophiles like sodium bisulfite and thiophenols causes even pteridines that are unreactive towards water or alcohols to undergo covalent addition reactions. Thus, pteridin-7-one smoothly adds the named S-nucleophiles in a 1 1 ratio to C-6 (65JCS6930). Similarly, pteridin-4-one (73) yields adducts (74) in a 2 1 ratio at C-6 and C-7 exclusively (equation 14), as do 4-aminopteridine and lumazine with sodium bisulfite. Xanthopterin forms a 7,8-adduct and 7,8-dihydropterin can easily be converted to sodium 5,6,7,8-tetrahydropterin-6-sulfonate (66JCS(C)285), which leads to pterin-6-sulfonic acid on oxidation (59HCA1854). 

Chemical Reactivity - Reactivity with Water No reaction Reactivity with Common Materials No reactions Stability During Transport Stable Neutralizing Agents for Acids and Caustics Destroy with sodium bisulfite or hypo and water, then neutralize with soda ash Polymerization Not pertinent Inhibitor of Polymerization Not pertinent. 

The enhanced reactivity of fluoroalkyl ketones is also manifested in the failure to stop the reaction with hydrogen cyanide at the stage of cyanohydrins Instead, oxazohdinones or dioxolanones are formed (equation 11) If, however, the reaction IS conducted under basic conditions with sodium bisulfite and sodium cyanide, the desired cyanohydrin can be prepared [ll ... 

Both 1- and 2-naphthylhydrazine have been shown to react in good yield with 2-hydroxy-3-naphthoic acid in the presence of sodium bisulfite to give, after acidic workup, dibenzocarbazole 30 and 31, respectively7 When either 1- or 2-naphthylhydrazine is heated with sodium bisulfite, dibenzocarbazoles 32 and 31, respectively, are isolated after acidic work-up7 It is suggested that loss of the hydrazine residue to form a bisulfite addition compound of the parent naphthol occurs initially further reaction of this adduct with naphthylhydrazine then affords, after work-up, the products. 

Bisulfite addition products are formed from aldehydes, methyl ketones, cyclic ketones (generally seven-membered and smaller rings), a-keto esters, and isocyanates, upon treatment with sodium bisulfite. Most other ketones do not undergo the reaction, probably for steric reasons. The reaction is reversible (by treatment of the addition product with either acid or base ) and is useful for the purification of the starting compounds, since the addition products are soluble in water and many of the impurities are not. ... 

II. Reaction of cytosine and uracil with sodium bisulfite. J. Biol. Chem. 248, 4060-4064. 

Salts of /3-styrenesulfonic acid have been prepared by the sulfonation of styrene with dioxane sulfotrioxide,2 by heating styrene with ammonium sulfamate,3 or by the reaction of styrene with sodium bisulfite in the presence of oxygen.4... 

Based on this tautometism, certain addition and replacement reactions at the hydroxyl or keto groups can be effected easily as with certain reactions of resorcinol and 2-naphthalenol. Thus, phloroglucinol forms a trioxime with hydroxylamine (120) it forms mono-, di-, and ttiaddition compounds with sodium bisulfite (121) it undergoes the Bucherer reaction with ammonia at room temperature (122) to give at first phloramine... 

Shapiro, R., Braverman, B., Louis, J. B., and Servis, R. E. (1973) Nucleic acid reactivity and conformation. II. Reaction of cytosine and uracil with sodium bisulfite. J. Biol. Chem. 248, 4060-4064. 

In order to generate SOI in acidic media, the reaction between sodium bisulfite and cerium ammonium nitrate should be employed. In (NH4)2Ce(N03)6, cerium has the oxidation state 4+. In acids, valence 4 cerium salts are strong oxidants. With the sulfite ion, the... 

The key butenolide needed by Buszek, for his synthesis of (—)-octalactin A, had already been prepared by Godefroi and Chittenden and coworkers some years earlier (Scheme 13.4).9 Their pathway to 10 provides it in excellent overall yield, in three straightforward steps from l-ascorbic acid. The first step entails stereospecific hydrogenation of the double bond to obtain L-gulono-1,4-lactone 13. Reduction occurs exclusively from the sterically less-encumbered ot face of the alkene in this reaction. Tetraol 13 was then converted to the 2,6-dibromide 14 with HBr and acetic anhydride in acetic acid. Selective dehalogenation of 14 with sodium bisulfite finally procured 10. It is likely that the electron-withdrawing effect of the carbonyl in 14 preferentially weakens the adjacent C—Br bond, making this halide more susceptible to reductive elimination under these reaction conditions. 

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