Schedule control

If the forward velocity of the ship is the state variable u, a best estimate of which is given by the Kalman filter, the gain scheduling controller can be expressed as... 

Bowen SE, Balster RL A direct comparison of inhalant effects on locomotor activity and schedule-controlled behavior in mice. Exp Clin Psychopharmacol 6 235— 247, 1998... 

Multiscale modeling of process operations. The description of process variables at different scales of abstraction implies that one could create models at several scales of time in such a way that these models communicate with each other and thus are inherently consistent with each other. The development of multiscale models is extremely important and constitutes the pivotal issue that must be resolved before the long-sought integration of operational tasks (e.g., planning, scheduling, control) can be placed on a firm foundation. 

Harris, R.A. Snell, D. and Lol, H.H. Effects of 7-amphetamine, monomethoxyamphetamines and hallucinogens on schedule controlled behavior. J Pharmacol Exp Ther 204 103-117, 1978,... 

Li, A. Marek, GJ. Seiden, L.S. and Vosmer, G. Long-term central 5-HT depletions resulting from repeated administration of MDMA enhance the effects of single administration of MDMA on schedule-controlled behavior in rats. Pharmacol Biochem Behav, in press. 

Cory-Slechta DA, O Mara DJ, Brockel BJ. 1998. Nucleus accumbens dopaminergic mediation of fixed interval schedule-controlled behavior and its modulation by low-level lead exposure. J Pharmacol Exp Ther 286 794-805. 

Cory-Slechta DA, Pazmino R, Bare C. 1997a. The critical role of nucleus accumbens dopamine systems in the mediation of fixed interval schedule-controlled operant behavior. Brain Res 764 248-256. 

Newland C, Yezhou S, Logdberg B, et al. 1996. In utero lead exposure in squirrel monkeys Motor effects seen with schedule-controlled behavior. Neurotoxicol Teratol 18 33-40. 

Rice DC, Gilbert SG, Willes RF. 1979. Neonatal low-level lead exposure in monkeys Locomotor activity, schedule-controlled behavior, and the effects of amphetamine. Toxicol Appl Pharmacol 51 503-513. 

Gerstenberger, S.L., J. Pratt-Shelley, M.S. Beattie, and J.A. Dellinger. 1993. Mercury concentrations of walleye (,Stizostedion vitreum vitreum) in 34 northern Wisconsin lakes. Bull. Environ. Contam. Toxicol. 50 612-617, Gilbert, S.G., C.D. Munkers, T.M. Burbacher, and D.C. Rice. 1994. Effects of in utero methylmercury exposure on schedule controlled behavior in adult monkeys. Amer. Jour. Primatol. 33 211. 

Peele DB, Crofton KM (1987) Pyrethroid effects on schedule-controlled behavior time and dosage relationship. Neurotoxicol Teratol 9 387-394... 

Dietz DD, McMillan DE. 1978. Effects of mirex and Kepone on scheduled controlled responding. Pharmacologist 20 225. 

McMillan DE. 1982. Effects of chronic administration of pesticides on schedule controlled responding by rats and pigeons. In Chambers JE, Yarbrough JD, eds. Effects of chronic exposures to pesticides on animal systems. New York, NY Raven Press, 211-226. 

Goldberg SR, Risner ME, Stolerman IP, ReaviU C, Garcha HS (1989) Nicotine and some related compounds effects on schedule- controlled behaviour and discriminative properties in rats. Psychopharmacology 97 295-302... 

Helton DR, Modlin DL, Tizzano JP, Rasmussen K (1993) Nicotine withdrawal a behavioral assessment using schedule controlled responding, locomotor activity and sensorimotor reactivity. Psychopharmacology 113 205-210... 

The Schedule-Controlled Operant Behavior test guideline (OPPTS 870.6500) defines procedures for conducting studies of schedule-controlled operant behavior, one way of evaluating the rate and pattern of a class of learned behavior. The purpose of the guideline is to evaluate the effects of acute and repeated exposures on the rate and pattern of responding under schedules of reinforcement. Additional tests may be necessary to completely assess the effects of any substance on learning, memory, or behavioral performance. 

Aggression due to omission of reward, mostly In pigeons, also monkeys Conditioned history, schedule-controlled operant behavior, omit or infrequent reinforcement Competition for resources food, sex, protected niches Attack pecks or bites, threat display toward conspecific or suitable object... 

Chalt, L.D., and Balster, R.L. The effects of acute and chronic phencyclidine on schedule-controlled behavior In the squirrel monkey. J. Pharmacol. Exp. Ther. 204 77-87, 1978. 

Lukas, S., Brady, J., and Griffiths, R., Comparison of opioid self-injection and disruption of schedule-controlled performance in the baboon, J. Pharmacol. Exp. Thet , 238, 924, 1986. 

Step 9 Method maintenance Incorporate the new method or analyzer into the existing method maintenance systems for the site, to ensure that the method as practiced continues to meet the technical requirements for as long as it is in use. This is done by the receiver. Method maintenance systems may include check sample control-charting, intra-and/or inter-lab uniformity testing, on-site auditing, instrument preventive maintenance (PM) scheduling, control-charting the method precision and/or accuracy, etc. 

More in-depth behavioral tests are required if dose-related toxicant effects are noted in screening tests. These tests may also be required as part of more selective toxicological screening, such as for developmental neurotoxicity. Focused tests of neuromotor function and activity, sensory functions, memory, attention, and motivation help to identify sites of toxicant-mediated lesioning, aid in the classification of neurotoxicants, and may suggest mechanisms of action. Some of these tests, like the schedule-controlled operant behavior tests for cognitive function, require animal training and extensive operator interaction with the animals. 

Drug Enforcement Administration (DEA) lists GBL as a scheduled (controlled) substance. 

The FIA system consisted of TMI modules (Tecniques Mesura Instrumentacio), a five-channel peristaltic pump, an eight-channel injection valve, an eight-channel distributed valve, and a colorimeter connected to an interface and to an IBM-PC microcomputer. A specific application software, Qcontroll , was used for data acquisition, with a continuous historical trend, and a scheduled control program for sequential analysis. In a previous scheme as in Fig. 1, free enzymes were used and the whole system was calibrated for a linear range of 0.05-1.0 g of ethanol/ L of standard ethanol solutions, and the product of the reaction was passed through the colorimeter. 

Gavalas-Medici, R. Day-Magdaleno, S. R. Extremely low frequency, weal electric fields affect schedule-controlled behavior of monkeys. Nature 1976, 261, 256-258. 

Tolerance develops rapidly following acute or chronic treatment with peptidic or nonpeptidic delta agonists [67-71]. For example, Figure 3 shows dose-effect curves for SNC80 administered alone or 24 h after pretreatment with SNC80 (1.0-10 mg/kg) in an assay of schedule-controlled responding for food reinforcement in rhesus monkeys [71]. Under control conditions, SNC80... 

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