Rodent ulcers

Rodent ulcers An ulcerous cancer (basal cell carcinoma), usually affecting the face... 

Decubitus ulcer (e.g. bed sores, pressure sores) Diabetic ulcers Varicose ulcers Rodent ulcers Peptic ulcers Ulcer due to continuous pressure exerted on a particular area of skin often associated with bed-ridden patients Ulcers (e.g. diabetic leg ) caused by complications of diabetes Due to defective circulation, sometimes associated with varicose veins An ulcerous cancer (basal cell carcinoma), usually affecting the face Ulcer of the digestive tract, caused by digestion of the mucosa by acid and pepsin may occur in e.g. the duodenum (duodenal ulcer), or the stomach (gastric ulcer)... 

Close-Up of basal cell carcinoma (BCC), or rodent ulcer, on the forearm in a 100-year-old female patient. This is the most common form of shin cancer among fair-skinned people. It usually appears on the face and is caused by sun damage. (Dr. P. Marazzi/Photo Researchers, Inc.)... 

Other activities on the gastrointestinal system included antidiarrhoeal and gastroprotective effects. Satureja hortensis and Aloysia triphylla EOs inhibited castor oil induced diarrhoea in rodents [225, 255]. The EO of lavender and its components (linalool, linalyl acetate) and the EO of Cryptomeria japonica (ter-pin-4-ol and elemol) showed protective activities against acute ethanol/aspirin-induced gastric ulcers in rodents [200,254]. 

The wood is valuable as timber. In China, the bark and leaves are used for insecticide, for the treatment of skin diseases, and to heal sores and ulcers. In Korea, the bark is used for the treatment of rheumatisms, cold, and cough. In Cambodia, Laos, and Vietnam, an infusion of leaves is drunk to promote digestion. The anti-inflammatory property of the plan is confirmed in vitro and thought to be imparted by saponins, including kalopanaxsaponin A and pictoside A, which elicited significant anti-inflammatory and anti-oxidant activity in rodents (78-82). What is the dopaminergic activity of kalopanaxsaponin A and pictoside A ... 

Anaerobic bacteria in the colon produce significant quantities of methanethiol along with hydrogen sulfide. Rodent studies indicate that these substances are detoxified to thiosulfate by the action of a specialized detoxification system that operates in the mucous layer of the colon lining.2 The failure of this system may contribute to some diseases of the colon, such as ulcerative colitis. 

GI Injury and Ulcer Models Acute or chronic GI injury models are induced by various compounds or agents in rodents. Intragas trie administrations of concentrated ethanol (50-100%), sodium hydroxide (NaOH), acetic acid, and hydrochloric acid (HCl) have been shown to induce mucosal injury in fasted rats. Of these models, ethanol and HCL models are relevant to humans, mimicking alcohol consumption and overproduction of HCL in the stomach. GI ulcer models include administration of nonsteroidal anti-inflammatory drugs (NSAIDs) such as... 

Tularaemia results from systemic infection with the gram-negative bacteria Francisella tularensis. Wild rodents (in particular, hares) and other small-animal populations are the main reservoir of infection. In humans, most cases are sporadic, related to tick bites (Dermacentor) or direct contact with infected animals. Hunters are at greatest risk, but the disease also affects butchers, farmers, foresters, laboratory workers and veterinarians (Evans et al. 1985). The incubation period varies from 1 day to 10 days. The clinical manifestation is usually an ulcerated nodule at the point of inoculation, associated with enlargement and, later, breakdown of lymph nodes. Systemic symptoms and toxaemia may be severe. Minocycline is considered to be efficacious in most cases (100 mg twice per day for 4 weeks). 

IL-10" primate, rodent inhibits IFNy secretion Phase I/n rheumatoid arthritis, Crohns disease, ulcerative colitis... 

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