Protein interaction analysis

Sato, S., Y. Shimoda, A. Murakiet al. (2007). A large-scale protein-protein interaction analysis in Synechocystis sp. PCC6803. DNA Res 14 207-216. 

Although fully devoted to the Health Sector, Biacore offers a set of services, which might be of great interest to developmental activities in other industrial areas. Then-focus is on systems for protein interaction analysis, which yield data on the interactions between proteins and other molecules. Protein functionality and the elucidation of reaction mechanisms play an important key role in the development and production of industrial processes. Currently, their products are used in antibody characterization,... 

Maurel, D., Comps-Agrar, L., Brock, C., Rives, M. L., Bourrier, E., Ayoub, M. A., Bazin, H., Tinel, N., Durroux, T. Prezeau, L. et al. (2008). Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies Application to GPCR oligomerization. Nat. Methods J, 561-7. 

Kalkhof, S. et al. (2005a) Chemical cross-linking and high-performance fourier transform ion cyclotron resonance mass spectrometry for protein interaction analysis Application to a calmodulin/target peptide complex. Anal. Chem. 77, 495-503. 

Mullet D.R. et al. (2001) Isotope-tagged cross-linking reagents. A new tool in mass spectrometric protein interaction analysis. Anal. Chem. 73, 1927-1934. 

Schreiber G, Fersht AR (1995) Energetics of protein-protein interactions analysis of the barnase-barstar interface by single mutations and double mutant cycles, J Mol Biol, 248 -178 1X9... 

Ehlert, A., Weltmeier, F., Wang, X., et al. (2006). Two-hybrid protein-protein interaction analysis in Arabidopsis protoplasts establishment of a heterodimeiization map of group C and group S bZIP transcription factors. Plant J., 46, 890-900. 

The majority of protein-protein interaction analysis tools rely on information obtained from repositories such as BIND [156], DIP [157], MINT [158], and GRID [159]. Interaction data from public databases can be accessed directly to retrieve experimental information. Alternatively, protein-interaction data can be accessed via predictive tools such as STRING and InterWeaver. Identifying protein-protein interactions can provide clues beyond a functional role or subcellular location. It is possible to predict a protein s metabolic importance based on the density of edges connecting nodes, because it has been shown that nodes with a high density of connections are more hkely to contain essential genes [160]. 

Keywords Biacore Biosensors Immobilization and surface chemistry Protein chips Protein interaction analysis Surface plasmon resonance... 

ProtorP a protein—protein interaction analysis server. Bioinformatics (Oxford, England), 25, 413—414. 

Gao G, Williams JG, Campbell SL (2004) Protein-protein interaction analysis by nuclear magnetic resonance spectroscopy. Methods Mol Biol 261 79-92... 

Sensitivity and specificity of in situ proximity hgation for protein interaction analysis in a model of steatohepatitis with Mallory-Denk bodies. PLoS One, 9(5). http // dx. doi.org/10.1371 /joumal.pone.0096690. 

The human genome can be investigated at the proteome level through direct small molecule-gene product (protein) interactions using activity/affinity-based approaches. Such small molecule-protein interaction analysis serves several objectives and can be performed directly with cells, cell extracts, or alternatively applying isolated proteins in a parallel maimer. 

Protein-Protein Interactions. Methods and Applications, ed. H. Fu R 90 G. Gao, J.G. Williams and S.E. Campbell, Protein-Protein Interaction Analysis by Nuclear Magnetic Resonance Spectroscopy , p. 79 Vol. 278, 2004... 

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