Activity Vs Affinity

It has been amply demonstrated that the very presence of the most appropriate and suitable design into a proposed drug molecule is not a sufficient evidence to ensure positive biological activity. 

Example Legitimate, viable, and noticeable competition occurring with a specific receptor looking for the available occupied space by other suitable segments of the drug molecule may inhibit binding phenomenon predominantly, and preclude activity distinguishably. 

Cardinal Parameters for Exhibiting Biological Activity The three major and prominent cardinal parameters for exhibiting apparent biological activity are as given below  

Important Features Following are certain important features to expatiate activity Vs affinity  

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