Propionic acid sodium salt

Propionic acid sodium salt. See Sodium propionate... 

Synonyms Propanoic add sodium salt Propionic acid sodium salt DeSnilion Sodium salt of propionic add Empiriced C3H5O2 Na CjHjNaOj xHjO Formula CHjCHjCOONa... 

Structure 2.2 3-(Trimethylsilyl) propionic-2,2,3,3-D4 acid, sodium salt. 

Phenylbutyl phosphinic acid 2-Ethylhexanoic acid, sodium salt 1-Chloroisobutyl propionate Ammonium n-butyl sulfate Hydroxybenzotriazole hydrate N,N -Dicyclohexylcarbodiimide... 

In 2 N hydrochloric acid (0.5 ml) was dissolved 2-(4-amino-3-carboxymethylphenyl)propionic acid disodium salt, 53 mg, 0.2 mmol). Sodium nitrite (14 mg, 0.2 mmol) was added to the resulting solution under stirring and chilling with ice. The mixture was stirred for 30 minutes under chilling with ice. The mixture was then neutralized with a chilled aqueous saturated sodium acetate solution. To the neutralized mixture was added a solution of thiophenol (0.02 ml, 0.2 mmol) in 6 N aqueous sodium hydroxide solution (0.1 ml), and the mixture was stirred for 2 hours at room temperature. The reaction mixture was then made acidic by addition of 2 N hydrochloric acid, and extracted with ethyl acetate. The ethyl acetate portion was extracted with an aqueous saturated sodium hydrogen carbonate solution. The aqueous portion was then made acidic by addition of 6 N hydrochloric acid and extracted with ethyl acetate. The ethyl acetate portion was washed successively with water and an aqueous saturated sodium chloride solution, and dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure to give 28 mg (yield 45%) of the 2-(3-carboxymethyl-4-phenylthiophenyl)propionic acid. 

E281 ethylformic acid, sodium salt, hydrate methylacetic acid, sodium salt, hydrate sodium propanoate hydrate sodium propionate hydrate. 

As an excipient, sodium propionate is used in oral pharmaceutical formulations as an antimicrobial preservative. Eike propionic acid, sodium propionate and other propionic acid salts are fungistatic and bacteriostatic against a number of Gram-positive cocci. Propionates are more active against molds than is sodium benzoate, but have essentially no activity against yeasts see Section 10. 

Acetylamino)-5[[(2-(hydroxy-ethyDamino] carbonyl]-2,4,6-triiodobenzoic acid 3-Amino-alpha-ethyl-2,4,6-tri-iodobenzene-propanoic acid Alpha-Ethyl-3-hydroxy-2,4,6-triiodobenzene-propionic acid 3-(Acetylethylamino)-2,4,6-tri-iodobenzene-propionicacid 3 - [ [(Dimethylamino)-methylenel amino]-2,4,6-triiodobenzene-propanoic acid Sodium salt Calcium salt... 

See Isoamyl propionate Isopentyi pyruvate. See Isoamyl pyruvate Isopentyi salicylate. See Isoamyl salicylate Isopentyi valerate. See Isoamyl valerate Isopentyi xanthic acid, sodium salt. See Sodium isoamyl xanthate Isophenphos. See Isofenphos Isophorol, dihydro-. See Trimethylcyclohexanol Isophorone... 

Luprenal . See Polyacrylic acid Lupromag . See Magnesium propionate Luprosil NC 64. See Ammonium propionate Luprosll Salt See Calcium propionate Luprosil Sodium Salt. See Sodium propionate Luprosll Special. See Calcium propionate Luprosil . See Propionic acid Lupulin. See Lupulin (Humulus lupulus)... 

It is well known that spatially-hindered phenols have antioxidant properties [3, 4]. Therefore, the test subjects used were preparations that are spatially-hindered phenols potassium phenosan (2,6-ditert-butyl-4-hy-droxyphenyl-propionic acid potassium salt) and anphen sodium (1-N-(acetylamido) -1 - (3,5-di-tert-butyl-4-hydroxybenzyl)-methyl-malonate). 

Preparation of 3- 4-Benzoylphenyl)propionyl-[ H Phe-tRNA. tRNA from yeast (Boehringer, Mannheim) is charged with [ H]Phe (11 Ci/mmole, Amersham) according to Bartmann et al. a 75-90% charging of the Phe-tRNA is attained. ( HJPhe-tRNA " (5 nmoles) is dissolved in 0.2 ml of 0.05 M HEPES (Af-2-hydroxyethylpiperazine-Y -2-ethanesulfonic acid) sodium salt, pH 6.8, and 3-(4-benzoylphenyl)-propionic acid A -hydroxysuccinimide ester (30 mg) in freshly distilled dimethyl sulfoxide (0.9 ml) is added. After the mixture is incubated for 3 hr at 37°, potassium acetate at pH 5 is added to 2% and the tRNA is precipitated with 2 volumes of ethanol for 1 hr at —20°. The precipitate is washed twice with ethanol and stored dry at —20°. 

Sodium propionate Sodium ethanecarboxylate Sodium propanoate Propanoic acid, sodium salt Whit-Bioban-S Deketon Impedex Mycoban Napropion Ocuseptine Propi-Ophtal Propiofar Propion PropisolPro E 281. 

Trimethyl-l, 3-pentanediol isobutyrate Propanoic acid octyl ester. See Octyl propionate Propanoic acid sodium salt. See Sodium propionate... 

Propionates. Propionic acid [79-09-4], C2H 02, and its calcium and sodium salts ate effective mold inhibitors. They ate particularly useful in yeast-leavened baked products because they do not affect the activity of yeast. In addition to being widely used in baked goods, they ate used as mold inhibitors in cheese foods and spreads (77). 

Analgesic and antipyretic ibuprofen, 2-(p-isobutylphenyl)propionic acid, is converted to its monohydroxyaluminum salt by converting the acid to its sodium salt using dilute caustic, foUowed by concurrent addition of equimolar amounts of aluminum nitrate and sodium bicarbonate (84). This salt can also... 

Fenoprofen, 2-(3-phenoxyphenyl)propionic acid, is made into its monohydroxyalurninum or dihydroxyalurninum salt by reaction of the sodium salt of the acid with aluminum nitrate or chloride under pH control (90,91). The aluminum salt, which is hydroly2ed in the stomach, is more palatable for arthritis treatment (92,93). 

The anti-inflammatory agent Oxapro2in, 2-(4,5-diphenyl-2-oxa2ole)propionic acid mono aluminum and dihydroxyalurninum salts, is made by reaction of the sodium salt with aluminum sulfate under controlled conditions (96). Again, the aluminum salts of many carboxylic acid based dmgs are less irritating, ulcerous, and/or toxic, and have a more pleasant taste than their parent acids. 

Lactisole [13794-15-5] the sodium salt of racemic 2(4-methoxyphenoxy)propionic acid, is a sweet-taste inhibitor marketed by Domino Sugar. It was affirmed as a GRAS flavor (FEMA no. 3773). At a concentration of 100 to 150 ppm, lactisole strongly reduces or eliminates the sweet taste of a 10% sugar solution. This inhibition appears to be receptor-related because lactisole also inhibits the sweet taste of aspartame. The 5 -( —)-enantiomer [4276-74-8] (38), isolated from roasted coffee beans, is the active isomer the i -(+)-enantiomer is inert (127). 

Propionic acid, 2-bromo-3-(3-indolyl)-methyl ester rearrangement, 4, 279 Propionic acid, 3-(3,4-dimethyoxyphenyl)-dihydrocoumarin synthesis from, 3, 848 Propionic acid, indolyl-synthesis, 4, 232 Propionic acid, 3-(l-indolyl)-sodium salt pyrolysis, 4, 202 Propionic acid, 3-(3-indolyl)-intramolecular acylation, 4, 220, 221 Propionic acid, 3-phenoxy-chroman-4-one synthesis from, 3, 855 Propionic acid, 3-(3-phenylisoxazoI-5-yl)-bromination, 6, 25... 

Reaction of etio acid 67 with N,N-dimethylthioformamidoyl chloride probably gives initially the mixed anhydride 71 this is not isolated but undergoes O to S carbonyl migration to the anhydride 72. Saponification then leads to the thioacid 73. Reaction of the sodium salt of the acid witli bromochloromethane affords cloticasone propionate (74). The corresponding reaction with hioniofluoromethane leads to fluticasone propionate (75) [16]. 

This ester (70 g) and diethyl carbonate (250 mg) were stirred at 90°C to 100°C while a solution of sodium ethoxide [from sodium (7.8 g) and ethanol (1 54 ml)] was added over 1 hr. During addition, ethanol was allowed to distill and after addition distillation was continued until the column heat temperature reached 124°C. After cooling the solution to 90°C, dimethyl sulfate (33 ml) was followed by a further 85 ml of diethyl carbonate. This solution was stirred and refluxed for 1 hr and then, when Ice cool, was diluted with water and acetic acid (10 ml). The malonate was isolated in ether and fractionally distilled to yield a fraction boiling at 148°C to 153°C/0.075 mm, identified as the alpha-methyl malonate. This was hydrolyzed by refluxing for 1 hr at 2.5N sodium hydroxide (350 ml) and alcohol (175 ml), excess alcohol was distilled and the residual suspension of sodium salt was acidified with hydrochloric acid to give a precipitate of the alpha-methyl malonic acid. This was decarboxylated by heating at 180°C to 200°Cfor 30 minutes and recrystallized from petroleum ether (BP 80°C to 100°C) to give 2-(2-fluoro-4-biphenylyl)propionic acid, MP 110°C to 111°C. 

A solution of 5.0 g of a-ethyl-(3-(aminophenyl)propionic acid in 100 ml of water containing 5 ml of concentrated hydrochloric acid was added over a period of h hour to a stirred solution of 3.2 ml of Iodine monochioride in 25 ml of water and 25 ml of concentrated hydrochloric acid heated to 60°C. After addition was complete, the heating was continued for h hour longer at 60° to 70°C. A black oil separated which gradually solidified. The mixture was then cooled and sodium bisulfite was added to decolorize. Recrystallization of the product from methanol gave about 8 g of a-ethyl-(3-(2,4,6-triiodo-3-aminophenyl-pro-pionic acid, MP 147° to 150°C. The product could be further purified by precipitation of its morpholine salt from ether solution and regeneration of the free amino acid by treatment of a methanol solution of the morpholine salt with sulfur dioxide. The pure amino acid had the MP 155° to 156.5°C (corr). 

Type iii-b This reaction leads to products (67). The electrochemical oxidation of the sodium salts of acetic, propionic, and isovaleric acids in the presence of ethylenic compounds bearing electron-withdrawing substituents gives 1,2-dialkylated adducts as the main products. A methyl radical generated from an acetate ion reacts with diethyl fumarate to give diethyl 2,3-dimethylsuccinate in 80% yield [106]. 

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