Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Poly vinyl pyrrolidone

Poly(vinyl pyrrolidone) (PVP) was introduced by the Germans in World War II as a blood plasma substitute.A water-soluble polymer, its main value is due to its ability to form loose addition compounds with many substances. [Pg.474]

The photolysis of poly(vinyl pyrrolidone) (3.52) was investigated in aqueous solutions in the presence of oxygen [1093, 1094, 1435]. The reaction was found to be dependent on the polymer concentration in water but apparently independent of the pH value. The initiation reaction normally occurs as chain scission and hydrogen abstraction  [Pg.150]

During the propagation reaction, quantities of monomer are formed, especially at elevated temperatures, probably as an unzipping reaction  [Pg.150]

In addition, chain scission may occur, via a disproportionation mechanism  [Pg.150]

The monomer formed during the degradation process may repolymerize. [Pg.150]


Poly(vinyl pyrrolidone). Another commercial polymer with significant usage is PVP (7). It was developed ia World War II as a plasma substitute for blood... [Pg.317]

In addition to its water solubility poly(vinyl pyrrolidone) is soluble in a very wide range of materials, including aliphatic halogenated hydrocarbons (methylene dichloride, chloroform), many monohydric and polyhdric alcohols (methanol, ethanol, ethylene glycol), some ketones (acetyl acetone) and lactones (a-butyrolactone), lower aliphatic acids (glacial acetic acid) and the nitro-paraffins. The polymer is also compatible with a wide range of other synthetic polymers, with gums and with plasticisers. [Pg.475]

Occasionally, water-soluble plastics are required. Poly(vinyl alcohol) is commonly the first to be considered but some cellulose ethers, polyethylene oxides, poly(vinyl pyrrolidone) and A-substituted polyamides are among many possible alternatives. [Pg.897]

FIGURE 9.22 Analysis of poly(vinyl pyrrolidone). Eluent 0.1 M Tris buffer, pH 7. Flow rate I ml/ min. Columns PSS Suprema 10 /itm, 100 + 1000, 8 x 300 mm. Oven temp 30°C. Detection Rl. Standards PSS polyvinylpyridin standards. [Pg.296]

Water-soluble polymers eomprise a major elass of polymerie materials and are used in a wide variety of applieations. Synthetie water-soluble polymers inelude poly(vinyl aleohol), poly(aerylamide), poly(aerylie aeid), poly(ethylene oxide), poly(vinyl pyrrolidone), eellulosies, and many eopolymers of these types. Their end uses are quite varied and their applieations depend mainly on their viseosify-ing, rheologieal, and surfaee-aetive properties (1). For example, poly (vinyl aleohol) is used in adhesives, fibers, textile and paper sizing, paekaging, as a stabilizer for emulsion polymerization, and as a preeursor for the manufaeture of poly(vinyl butyral), whieh is used in automotive windshields. Poly(vinyl aleohol) is also the world s largest volume, eommodity, water-soluble polymer. [Pg.559]

Galactosylated chitosan prepared from lactobionic acid and chitosan with l-ethyl-3-(3-dimethylaminopropyl)-carbodiimideand N-hydroxysuccinimide was a good extracellular matrix for hepatocyte attachment [155] (Fig. 4). Furthermore, graft copolymers of galactosylated chitosan with poly(ethylene glycol) or poly(vinyl pyrrolidone) were useful for hepatocyte-targeting DNA carrier [156,157]. [Pg.170]

Poly(vinyl pyrrolidone) poly(N,N-dimethylacryl amide) ... [Pg.221]

Notes Cellulose (Whatman) PTMSP, poly(trimethyl silyl propine) PS, polystyrene PP, polypropylene PE, polyethylene PA 66, polyamide 66 PA 6, polyamide 6 PVP, poly(vinyl pyrrolidone) PPO, poly(2,6-dimetyl-l,4-phenylene oxide) PMMA, poly(methyl methacrylate) PETP, polyethylene terephthalate) Irganox 1010 is a Ciba anti-oxidant. [Pg.471]

Figure 6 (A) Non-isothermal chemiluminescence runs for oxidation of polystyrene (PS), polyethylene terephthalate) (PETP) and polyfmethyl methacrylate) (PMMA), in oxygen, heating rate 2.5°C/min. (B) Non-isothermal chemiluminescence runs for oxidation of polypropylene (PP), polyamide 6 (PA 6), poly(vinyl pyrrolidone) (PVP), polyethylene (PE) and polyamide 66 (PA 66), in oxygen, heating rate 2.5°C/min. Figure 6 (A) Non-isothermal chemiluminescence runs for oxidation of polystyrene (PS), polyethylene terephthalate) (PETP) and polyfmethyl methacrylate) (PMMA), in oxygen, heating rate 2.5°C/min. (B) Non-isothermal chemiluminescence runs for oxidation of polypropylene (PP), polyamide 6 (PA 6), poly(vinyl pyrrolidone) (PVP), polyethylene (PE) and polyamide 66 (PA 66), in oxygen, heating rate 2.5°C/min.
An illustrative example is the work of Clark et al, on the conformation of poly(vinyl pyrrolidone) (PVP) adsorbed on silica 0). These authors determined bound fractions from magnetic resonance experiments. In one instance they added acetone to an aqueous solution of PVP in order to achieve theta conditions for this polymer. They expected to observe an increase in the bound fraction on the basis of solvency effects as predicted by all modern polymer adsorption theory (2-6), but found exactly the opposite effect. Their explanation was plausible, namely that acetone, with ability to adsorb strongly on silica due to its carbonyl group, would be able to partially displace the polymer by competing for the available surface sites. [Pg.54]

Figure 3. Experimental displacement isotherms of poly (vinyl pyrrolidone) from silica in water/displacer mixtures. NMP N-methyl pyrrolidine PYR Pyridine NEM N-ethyl morpholine DMSO dimethylsulfoxide... Figure 3. Experimental displacement isotherms of poly (vinyl pyrrolidone) from silica in water/displacer mixtures. NMP N-methyl pyrrolidine PYR Pyridine NEM N-ethyl morpholine DMSO dimethylsulfoxide...
Lai, M.C., Hageman, M.J., Schowen, R.L., Borchardt, R.T., and Topp, E.M. 1999a. Chemical stability of peptides in polymers. 1. Effect of water on peptide deamidation in poly(vinyl alcohol) and poly(vinyl pyrrolidone) matrixes. J. Pharm. Sci. 88, 1073-1080. [Pg.94]

With continuous development of systems for controlled drug release, new materials are being used whose influence on peptide stability must be carefully examined. Thus, the model hexapeptide Val-Tyr-Pro-Asn-Gly-Ala (Fig. 6.30) embedded in poly (vinyl alcohol) and poly(vinyl pyrrolidone) matrices had rates of deamidation that increased with increasing water content or water activity, and, hence, with decreasing glass transition temperature (Tg). However, the degradation behavior in the two polymers differed so that chemical reactivity could not be predicted from water content, water activity, or T% alone. Furthermore, the hexapeptide was less stable in such hydrated polymeric matrices than in aqueous buffer or lyophilized polymer-free powders [132],... [Pg.327]

Kollidon Poly(vinyl pyrrolidone) General Aniline Film... [Pg.672]

Because of acid-catalyzed hydrolysis of N-vinylpyrrolidone in water, polymerization was carried out in organic solvent - DMF. Three types of samples of poly(methacrylic acid) were used syndiotactic - obtained by radiation polymerization, atactic - obtained by radical polymerization, and isotactic - obtained by hydrolysis of isotactic poly(methyl methacrylate). It was found that in all cases the rate enhancement appeared in comparison with the blank polymerization (without template). The rate enhancement became more pronounced with increasing chain length and syndiotacticity of the template. According to the authors, the rate enhancement is connected with the stronger complex formation between poly(vinyl pyrrolidone) and syndiotactic poly(methacrylic acid) then with isotactic template. This conclusion was supported by turbimetric titration in DMF/DMSO system and by model considerations. It is worth noting, however, that... [Pg.30]

POLY(ETHYLENE OXIDE), PEG, AND POLY(VINYL PYRROLIDONE), PVP, AS TEMPLATES... [Pg.36]

The most examined monomers for template polymerization have been either acrylic or methacrylic acids. This is probably because many polymers, such as poly(ethylene oxide), PEG, and poly(vinyl pyrrolidone), PVP, form complexes with poly(acrylic acid). [Pg.36]

A very interesting modification of the system was examined by Ferguson and McLeod. The authors replaced poly(vinyl pyrrolidone) with copolymers vinyl pyrrolidone-styrene or vinyl pyrrolidone-acrylamide. It was found that the mechanism of polymerization is the same as in the presence of homopolymer (PVP). However, the rate of polymerization decreases rapidly when vinyl pyrrolidone concentration in copolymer decreases. The concentration of vinyl pyrrolidone residues was kept equimolar to the concentration of acrylic acid. It was stressed that structure of template and, in the case of copolymeric template, sequence distribution of units play an important role in template effect. [Pg.37]

When the ratio of template to acid is close to 0.5, the viscosity of the product is more than 3 times higher than the viscosity of the polymer obtained without the template. PEO participates in the change of local concentration by interaction with carbonyl groups, but not in the activation. Solution of LiCl in N-methylpyrrolidone with PlOCeHsls was found very effective system for synthesis of amides by the direct reaction of acids with amines in the presence of polymeric matrix. High molecular weight poly(aminoacids) obtained by direct polycondensation reaction, promoted by triphenyl phosphite and LiCl in the presence of poly(vinylpyrrolidone), were synthesized by Higashi et al The results for polymerization of L-leucine in the presence of poly(vinyl pyrrolidone) are presented in the Table 6.3. [Pg.79]


See other pages where Poly vinyl pyrrolidone is mentioned: [Pg.799]    [Pg.474]    [Pg.477]    [Pg.560]    [Pg.573]    [Pg.201]    [Pg.874]    [Pg.221]    [Pg.344]    [Pg.22]    [Pg.298]    [Pg.536]    [Pg.118]    [Pg.472]    [Pg.590]    [Pg.118]    [Pg.275]    [Pg.86]    [Pg.87]    [Pg.130]    [Pg.109]    [Pg.152]    [Pg.40]    [Pg.43]   
See also in sourсe #XX -- [ Pg.36 , Pg.45 , Pg.79 , Pg.99 , Pg.107 ]




SEARCH



Poly(A-vinyl pyrrolidone)

Poly(N-vinyl pyrrolidone)

Poly(Vinyl Pyrrolidone) (PVP)

Poly[vinyl

Pyrrolidon

Pyrrolidone

Pyrrolidones

Vinyl pyrrolidone

© 2024 chempedia.info