Halogenated aliphatic hydrocarbons

Di- and poly-halogenated aliphatic hydrocarbons. No general procedure can be given for the preparation of derivatives of these compounds. Reliance must be placed upon their physical properties (b.p., density and refractive index) and upon any chemical reactions which they undergo. 

Callen DF, Wolf CR, Philpot RM. 1980. Cytochrome P-450-mediated genetic activity and cytotoxicity of seven halogenated aliphatic hydrocarbons in Saccharomyces cerevisiae. Mutat Res 77 55-63. 

Dickson AG, Riley JP. 1976. The distribution of short-chain halogenated aliphatic hydrocarbons in some marine organisms. Mar Pollut Bull 7 167-169. 

Mersch-Sundermann V, Muller G, Hofmeister A. 1989. Examination of mutagenicity of organic microcontaminations of the environment. IV. Communication the mutagenicity of halogenated aliphatic hydrocarbons with SOS-Chromotest. Zentralbl Hyg Umweltmed 266-271. 

Roldan-Aijona T, Garcia-Pedrajas MD, Luque-Romero FL, et al. 1991. An association between mutagenicity in rodents for 16 halogenated aliphatic hydrocarbons. Mutagenesis 6 199-205. 

Crebelli, R., Andreoli, C., Carere, A., Conti, L., Crochi, B., Cotta-Ramusino, M., Benigni, R. Toxicology of halogenated aliphatic hydrocarbons Structural and molecular determinants for the disturbance of chromosome segregation and the induction of lipid peroxidation. Chem. Biol. Interact. 1995, 98, 113-129. 

Dibromoethane is a halogenated aliphatic hydrocarbon produced when gaseous ethylene comes in contact with bromine. The mixing of ethylene and bromine is accomplished in a variety of ways. One of the more common manufacturing processes involves a liquid-phase bromination of ethylene at 35°-85°C. After the bromination of ethylene, the mixture is neutralized to free acid and then purified by distillation. Other methods of 1,2-dibromoethane formation include the hydrobromination of acetylene and a reaction of 1,2-dibromoethane with water (Fishbein 1980 HSDB 1989). 

Heilman B, Brandt I. 1986. Effects of carcinogenic halogenated aliphatic hydrocarbons on [ H] thymidine incorporation into various organs of the mouse A comparison between 1,2-dibromoethane and 1,2-dichloroethane. Mutat Res 163 193-199. 

Wilson, B.H., Smith, G.B., and Rees, J.F. Biotransformations of selected alkylbenzenes and halogenated aliphatic hydrocarbons in methanogenic aquifer material a microcosm study, Environ. Sci. Technol, 20(10) 997-1002,1986. 

Torkelson TR, Rowe VK Halogenated aliphatic hydrocarbons. In Clayton GD and Clayton FE (eds) Patty s Industrial Hygiene and Toxicology, Vol 2B, Toxicology, pp 3568-3572. New York, Wiley-Interscience, 1981... 

Tbrkelson, TR, Rowe VK Halogenated aliphatic hydrocarbons containing chlorine. 

The FEED technology effectively treats hydrocarbons (e.g., gasoline and fuel oils), non-halogenated aliphatic hydrocarbons, and polycyclic aromatic hydrocarbons (PAHs) such as naphthalene, phenanthrene, and benzo(a)pyrene. 

Budavari, S., ed. (1996) The Merck Index, 12th Ed., Whitehouse Station, NJ, Merck Co., p. 297 Callen, D.F., Wolf, C.R. Philpot, R.M. (1980) Cytochrome P-450 mediated genetic activity and cytotoxicity of seven halogenated aliphatic hydrocarbons in Saccharomyces cerevisiae. 

Crebelli, R., Conti, G, Conti, L. Carere, A. (1984) Induction of somatic segregation by halogenated aliphatic hydrocarbons in Aspergillus nidulans. Mutat. Res., 138, 33-38... 

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