Copy papers

Correlations on paper panels are made easier if a type log has been creafed of a fypical and complete sequence of the area. If this log is available as a transparency, it can be easily compared against the underlying paper copy. Type logs are also handy if the reservoir development has to be documented in reports or presentations. 

After perusal of these process options, the engineer asks the computer to select five designs for further study, and the oomputer produces a paper copy of the flowsheet and design parameters... 

This method of data collection uses Portable Document Format (PDF) Forms. This approach is flexible and inexpensive. A number of commercial software packages such as Adobe Acrobat, LaText, and Microsoft Word and free software such as Python and R are used to create the PDF forms. Paper copies of the PDF forms may be used as an intermediate data collection. Electronic versions are completed at each site with Adobe Reader software. Completed forms are submitted on a CD or faxed as Extended Markup Language (XML)... 

Additional copies may be purchased from the U.S. Government Printing Office (GPO) and/or the National Technical Information Service (NTIS) as indicated. NTIS prices are for paper copy. Microfiche copies, at 6.95, are also available from NTIS. Prices from either source are subject to change. 

Another aspect of the GLP requirements that is often overlooked when only electronic systems are used is that, in the event of a system failure, a back-up paper version should be available and reasonably located nearby. For example, should an electronic SOP system fail, it is unlikely that a government inspector will consider one paper copy of the SOP adequate for a large facility that includes held sites, animal rooms, an analytical laboratory, an immunology laboratory, and a clinical pathology laboratory. 

The assumption was that the summary portion of the report (including text and summary tables) would be saved as a PDF file, directly from the word processor used to create the report, and not scanned from a paper copy with a PDF file created from the image. However, owing to the variety of systems that may be used to create tables and appendices of data in the laboratory, it was recognized that some of these might require that PDF files be created from the scanned paper copy. 

In the electronic millennium that we have just entered, the ability to construct a complete electronic study in a final form identical with the paper copy must be provided. We, as part of the regulated community, must be ready for change. New skills must be learned. IT organizations must provide support for the document production process. We must learn to think electronic first and paper last. 

Disclaimer All MMWR HTML versions of articles are electronic conversions from ASCII text into HTML. This conversion may have resulted in character translation or format errors in the HTML version. Users should not rely on this HTML document, but are referred to the electronic PDF version and/or the original MMWR paper copy for the official text, figures, and tables. An original paper copy of this issue can be obtained from the Superintendent of Documents, U.S. Government Printing Office (GPO), Washington, DC 20402-9371 telephone (202) 512-1800. Contact GPO for current prices. 

The first and obvious technical access barrier is the availability of data in digital form. While most modern documents are born digital , a lot of libraries will still only archive paper copies of scientific literature, although more and more... 

With the advance in computer technology and the increased use of computer networks, many laboratories are making SOPs available in electronic form via read-only central computer files. Electronic SOPs help ensure that aU personnel are using the current version of an SOP, reduce or eliminate the need for distribution of paper copies of the SOPs, and reduce or eliminate the need for follow-up to ensure that SOP manuals are updated properly. A master, hard copy version of the SOPs that is authorized, signed, and dated by management still must be retained in the archives, and the historical file of SOPs should also contain hard copy versions that have been authorized, signed, and dated by management. Like hard copy SOPs, electronic SOPs must be readily available to study personnel. 

The original signed SOPs must be in a controlled location, but they must be accessible to all analysts. Paper copies or electronic copies can be used to make the SOPs available. It is very important, however, that the laboratory has a system in place to guarantee that only the most recent revision is in use. All older revisions of the SOPs must be archived so the laboratory has a complete history of the procedure. 

Verify ability to generate paper-copy of electronic records Verify controls for system ( closed or open )... 

Data records archive/retention/retrieval (electronic records and paper copy)... 

INDs. On March 26,2002, the FDA published final guidance on the submission of INDs in electronic format to the CBER (http //www.fda.gov/cber/ gdlns/eind.pdf). Once the IND submission to CBER is posted on public docket 92S-0251, we will be capable of accepting INDs submitted to CBER in electronic format without paper copies. At this time, we are not extending this to INDs submitted to CDER. 

Comments Interested persons may submit to the Division of Dockets Management (see Addresses ) written or electronic comments on the draft guidance. Submit a single copy of electronic comments or two paper copies of any mailed comments, except that individuals may submit one paper copy. Comments are to be identified with the docket number found in brackets in the heading of this document. The draft guidance and received comments may be seen in the Division of Dockets Management between 9 00 a.m. and 4 00 p.m., Monday through Friday. 

Electronic signatures conform to emerging guidelines, or a paper copy with appropriate nonelectronic signatures is included. 

Acceptability of Electronic Submissions. In the Federal Register of March 20,1997 (62 FR13467), the Agency announced the establishment of a docket, number 92S-0251, where it will publish the submissions it will accept in electronic format. Once a Center has identified in the docket a submission type as one that can be processed, reviewed, and archived in an electronic-only format, you may provide the submission utilizing electronic media without any paper copies [21 CFR 11.1(d) and 11.2],... 

A paper copy that includes the handwritten signature of the sponsor authorized representative and the IND number to identify the electronic document and attachments. 

Electronic Signatures conform to emerging guidelines or a paper copy... 

Most submissions to the FDA are currently delivered on paper or as a combination of paper and electronic copy. Some FDA groups encourage fully electronic submissions others seem to discourage submissions without primary or secondary paper copies. A few request hyperlinked electronic versions others seem uncomfortable with hyperlinking. In Europe, Canada, Australia, and Japan, the situation is even more confused and confusing. 

Even before the CWC entered into force, the group of specialists approved some 900 NMR spectra recorded from 205 chemicals. Originally, it was decided to compile the accepted spectra as paper copies now the OCAD data is distributed on a DVD as pdf files. A first version of the resulting atlas of NMR spectra was certified in February 1998. The process of extending the OCAD, which is to be made available on request to member states, is in continuous progress. 

The main mechanism for effecting triggered release is to use pressure to break the shell, and hence release the core contents into the external phase. This is particularly useful when the active material is a high MW molecule (e.g. a protein). The applied pressure can be in the form of simple mechanical pressure (e.g. in carbon paper copying) or high shear conditions. A more subtle method, however, is to use osmotic pressure to break the capsule. This can occur if solvent molecules from the external phase are able to diffuse across the shell into the core. If the core contains molecules (e.g. polymer) which are not able to diffuse across the shell, then clearly there will be an osmotic pressure difference across the shell, which will drive solvent to try to enter the core, leading to possible shell rupture. 

Reproducing electronic records as paper copies or electronically displayed copies... 

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