Germinated barley foodstuff

Mitsuyama, K., T. Saiki, O. Kanauchi, HV088 et al. Treatment of ulcerative colitis with germinated barley foodstuff feeding a pilot study. Aliment Pharmacol Ther 1998 12(12) 1225-1230. 

HVHO Kanauchi O., T. Iwanaga, A. Andoh, et al. Dietary fiber fraction of germinated barley foodstuff attenuated mucosal damage and diarrhea, and accelerated the repair of the colonic mucosa in an experimental colitis. J Gastroenteol Hepatol 2001 16(2) 160-168. 

Mitsuyama. Germinated barley foodstuff feeding. A novel neutraceutical therapeutic strategy for ulcerative colitis. Digestion 2001 63 Suppl 1 60-67. 

HV143 Araki Y., Y. Fujiyama, A. Andoh, S. Koyama, O. Kanauchi, and T. Bamba. The dietary combination of germinated barley foodstuff plus Clostridium butyricum suppresses the dextran sulfate sodium-induced experimental colitis in rats. Scand J Gastroenterol 2000 35(10) 1060-1067. 

Effects of germinated barley foodstuff on microflora and short chain fatty acid production in dextran sulfate sodium-induced colitis in rats. Biosci Biotechnol Biochem 2000 64(9) 1794-1800. 

HV145 Kanauchi O., A. Andoh, T. Iwanaga, et al. Germinated barley foodstuffs attenuate colonic mucosal damage and mucosal nuclear factor kappa B activity in a spontaneous colitis model. J Gastroenterol Hepatol 1999 14(12) 1173-1179. 

HV146 Kanauchi O., T. Iwanaga, K. Mitsu-yama, et al. Butyrate from bacterial fermentation of germinated barley foodstuff preserves intestinal barrier function in experimental colitis in the rat model. J Gastroenterol Hepatol 1999 14(9) 880-888. 

HV147 Kanauchi O., K. Mitsuyama, T. Saiki, K. Agata, T. Nakamura, and T. Iwa-naga. Preventive effects of germinated barley foodstuff on methotrexate-induced enteritis in rats. Int J Mol Med 1998 1(6) 961-966. 

HV150 Kanauchi O., T. Nakamura, K. Agata, T. Fushiki, and H. Hara. Effects of germinated barley foodstuff in preventing diarrhea and forming normal feces in ceco colectomized rats. Biosci Bio-technolBiochem 1998 62(2) 366-368. 

FIV152 Kanauchi O., T. K. Agata, and T. Fushiki. Mechanism for the increased defecation and jejunum mucosal protein content in rats by feeding germinated barley foodstuff. Biosci... 

HV161 Kanauchi O., I. Serizawa, Y. Araki, et al. Germinated barley foodstuff, a pre-biotic product, ameliorates inflammation of colitis through modulation of the enteric environment. J Gastroenterol 2003 38(2) 134-141. 

HV170 Kanauchi O., T. Suga, M. Tochihara, et al. Treatment of ulcerative colitis by feeding with germinated barley foodstuff first report of a multicenter open control trial. J Gastroenterol 2002 37 Suppl 14 67-72. 

HV186 Kanauchi O., Y. Fujiyama, K. Mitsu-yama, et al. Increased growth of Bifidobacterium and Eubacterium by germinated barley foodstuff, accompanied by enhanced butyrate production in healthy volunteers. Int J Mol Med 1999 3(2) 175-179. 

Initial studies in our laboratory indicate that the gut microflora of patients with ulcerative colitis responds in a similar manner to that of healthy individuals upon prebiotic ingestion, that is, increased faecal bifidobacteria and/or lactobacilli (Kolida unpublished data). Germinated barley foodstuff (GBF), which is a mixture of glutamine-rich protein and hemicellulose-rich fibres, has been shown to alleviate colitic symptoms in animal models of ulcetative colitis and in colitic patients (Bamba et al. 2002 Araki et al. 2000). This foodstuff, although rich in readily fermented fibre, has not been assessed for its prebiotic capabilities. That is to say, that although a beneficial health effect has been observed upon ingestion of GBF, the impact of GBF fermentation upon the gut microflora, and in particular on relative numbers of bifidobacteria and lactobacilli, has not been determined. 

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