Non-tumorigenic

Sun, Y. Dwyer-Nield, L. D. Malkinson, A. M. Zhang, Y. L. Thompson,J. A. Responses of tumorigenic and non-tumorigenic mouse lung epithelial cell lines to electrophilic metabolites ofthe tumor promoter butylated hydroxytoluene. Chem.-Biol. Interact. 2003, 145, 41-51. 

The endpoint of the BALB/c CTA is the carcinogenic conversion from non-tumorigenic immortality to tumorigenicity resulting in focus formation and anchorage-independent growth [51]. 

Nishizuka, S., Winokur, S.T., Simon, M., Martin, J., Tsujimoto, H., and Stanbridge, E.J., Oligonucleotide microarray expression analysis of genes whose expression is correlated with tumorigenic and non-tumorigenic phenotype of HeLa X human fibroblast cells. Cancer Lett., 165, 210-209, 2001. 

Two reports presented evidence that CaMKI and its activators CAMKKa and CaMKKpJ are important in G1 progression of human cells in culture. In one study, WI-38 normal diploid fibroblasts were used whereas the other study used MCF-7 human breast cancer cells together with the non-tumorigenic MCF-10A clone. 

Tokiwa T, Yamazaki T, Xin W, Sugae N, Noguchi M, Enosawa S, et al. Differentiation potential of an immortalized non-tumorigenic human liver epithelial cell line as liver progenitor cells. Cell Biol Int 2006 30 992-98. 

Hester, S. D., Wolf, D. C., Nesnow, S., and Thai, S. F. (2006). Transcriptional profiles in liver from rats treated with tumorigenic and non-tumorigenic triazole conazole fungicides Propiconazole, triadime-fon, and myclobutanil. Toxicol Pathol 34, 879-894. 

Hester, S. D., and Nesnow, S. (2008). Transcriptional responses in thyroid tissues from rats treated with a tumorigenic and a non-tumorigenic triazole conazole fungicide. Toxicol Appl Pharmacol 221, 357-369. 

Inhibition of Tumorigenicity of Potently Tumorigenic PAHs by Non-Tumorigenic or Weakly Tumorigenic PAHs... 

The CSC levels of mouse-skin tumorigenic PAHs plus promoting/cocarcinogenic phenols and non-tumorigenic PAHs, acting individually or in concert, could not account for the observed response in CSC-painted animals. 

Carruba G, Webber MM, Quader ST, Amoroso M, Cocciadiferro L, Saladino F, Trosko JE, Castagnetta JE. Regulation of cell-to-cell communication in non-tumorigenic and malignant human prostate epithelial cells. Prostate 2002 50 73-82. 

Li, S.L. et al., Lowp53 level in immortal non-tumorigenic oral keratinocytes harboring HPV-16 DNA, Dwr. J. Cancer Biol Oral Oncol, 28B, 129, 1992. 

Li L, Adams LS, Chen S, Killian C, Ahmed A, Seeram NP (2009) Eugenia jambolana Lam. berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells. J Agric Food Chem 57 826-831... 

Human immortalised non-tumorigenic keratinocyte HaCaT cells (CeU Lines Service, Germany) were seeded mito the treated and untreated samples in the culture dishes and incubated at 37 °C for 4 days [10]. DMEM (high glucose) supplemented with 2mM L-glutamine solution and 10% fetal calf serum was used as the culmre medium. 

Kiebish, MA., Han, X., Cheng, H. and Seyfried, T.N. (2009) In vitro growth environment produces Upidomic aud elecirou trausport chaiu abuormalities iu mitochondria from non-tumorigenic astrocytes and brain tumours. ASN Neuro 1, e0(X)l 1. 

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