Mezlocillin sodium

Mezlocillin Sodium Mezlocillin sodium is not compatible with ciprofloxacin, metronidazole, aminoglycosides, and tetracyclines. 

Pethidine Hydrochloride Pethidine hydrochloride solutions are not compatible with barbiturates, aminophylline, morphine sulfate, sulfadiazine sodium, methicilline sodium, nitrofurantoin, phenytoin sodium, heparin sodium, sodium iodide, diethanolamine, sulfafurazol, acyclovir sodium, liposomal doxorubicin hydrochloride, frusemide, imipenem, and idarubicin. Visual incompatibilities are reported with mixtures of pethidine hydrochloride and cefoperazone sodium or mezlocillin sodium, nafcillin sodium and minocycline hydrochloride or tetracycline hydrochloride in 5% glucose injection.82 83... 

Phethenylate sodium Ammonium chloride Cyclofenil Methionine Ammonium sulfate Aminobenzoic acid Fibrinolysin Ammonium sulfamate Cyclamate calcium Ammonium thiocyanate Acetazolamide Clonidine HCl Tolonidine nitrate 2oxazo lamina d-Amphetamine Tanphetamin Ampicillin Mezlocillin Talampicillin... 

Admixture incompatibility Amiodarone IV in D5W, in a concentration of 4 mg/mL, forms a precipitate and is incompatible with the following drugs Aminophylline, cefamandole, cefazolin, mezlocillin, heparin (no amiodarone concentration stated), and sodium bicarbonate (amiodarone concentration of 3 mg/mL). 

Mezlocillin, piperacillin, and ticarcillin are parenteral antibiotics formulated as sodium salts, so prescribers must consider the sodium content of these antibiotics when administering them to patients with congestive heart failure. During their distribution phase, antipseudomonal penicillins achieve orfly low concentrations in the cerebrospinal fluid. Consequently, antipseudomonal penicillins are not among the drugs of first choice for meningitis therapy. 

Rx amoxicillin, ampicillin, bacampicillin, carbenicillin, cloxacillin, dicloxacillin, flucloxacillin, methicillin, mezlocillin, nafcillin, oxacillin, penicillin G benzathine, penicillin G potassium, penicillin Vpotassium, piperacillin, pivampicillin, pivme-cillinam, ticarcillin Penicillin and beta-lactamase inhibitors amoxicillin/ clavulanate potassium, ampicillin/sulbactam sodium, piperacillin sodium/ tazobactam sodium, ticarcillin disodium/clavulanate potassium Chemical Class Penicillin, natural... 

The precipitate was allowed to settle for 30 minutes, the solution was decanted from the precipitate, and the latter was again suspended in ether, filtered off and washed with anhydrous ether. After drying over P205 in a vacuum desiccator, the sodium salt of the mezlocillin was obtained in the form of a white solid substance. 

High doses of sodium penicillin can cause urinary potassium loss, presumably by acting as a non-absorbable anion in the distal tubule (30). Apparently by analogous mechanisms a variety of semisjmthetic peniciUins, including carbenicUhn, cloxacUhn, mezlocillin, nafcUhn,... 

Mezlodiiin Sodium. Sterile. USP. Mezlocillin (Mez-lin) is an acylureidopenicillin with an antibacterial spectrum similar to that of carbenicillin and ticarcillin however, there are some major differences. It is much more active against most Klebsiella spp.. P. aeruginosa, anaerobic bacteria (e.g.. Streptococcus fiiecalis and B.fragilis). and H. influenzae. It is recommended for the treatment of serious infections cau.sed by these organisms. 

Mezlocillin is not generally effective against jS-lactamase-producing bacteria, nor is it active orally. It is available as a white, crystalline, water-soluble sodium. salt for injection. Solutions. should be prepared freshly and, if not used within 24 hours, refrigerated. Mezlocillin and other acylureidopeni-c.v. Vms. wdaVit... 

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