Antibacterial spectrum

Cefmetazole (78) is a cephamycin-inspired cephalosporin differing from the mainstream compounds in having an aliphatic amide moiety attached to C-7. Its antibacterial spectrum is similar to the second generation agent cefoxitin. The synthesis starts with 7-aminocephalosporan-... 

The final sulphur-containing antibiotic proved be a highly active compound, superior in its antibacterial spectrum to all known tetracyclines. ... 

Greatly improved Gram-negative antibacterial spectrum, excellent lactamase stability... 

Since patients can rarely be relied upon to take (or be given) medication after fasting, and since itis common experience that doses are omitted more or less frequently the properties of doxycycline make it appear a promising successor to the first generation tetracyclines. This is even more likely since the antibacterial spectrum and activity is at least equal to that of tetracycline, and in the case of certain tetracycline-resistant bacteria doxycycline has (of all derivatives tested) shown the highest activity [35, 41]. 

Early detection of mastitis and immediate treatment reduces pathologic damage and increases the likelihood of eliminating the infection. Because therapy is given without identification of the pathogen involved, a product with a broad antibacterial spectrum is essential (4. The desirable kinetic and other properties of an intramammary antibiotic product for treatment in lactation have been summarized by Ziv (23). 

Carbapenems have the broadest antibacterial spectrum, covering both Gram-positive and Gram-negative bacteria and showing high resistance to most b lactamases but are susceptible to carbapenemases. 

In terms of mechanism of action, antibacterial spectrum, and indications for use, it is essentially no different than oxacillin and cloxacillin. Synonyms of this drug are diclocil, novapen, diclex, and others. 

In terms of antibacterial spectrum, this drug is similar to chlorotetracycline. It is used for the same indications. It belongs to the group of short-lasting tetracyclines. Synonyms of this drug are tetramycin, oxymycin, and others. 

Rifampicin is an antibiotic with a broad spectrum of use that differs from rifamicin SV (32.7.5), which is also used in medicine as an independent drug showing high efficacy when taken internally and having a broad antibacterial spectrum of activities. 

In terms of the antibacterial spectrum and region of use, enoxacin basically exhibits the same properties as norfloxacin. However, it is better absorbed from the gastrointestinal tract and has a longer half-life. Synonyms of this drug are bactidan, flumarc, and... 

Microbiology Sulfonamides have a broad antibacterial spectrum that includes gram-positive and gram-negative organisms. 

Cefotaxime can be used in infections due to beta-lactamase producing strains of H. influenzae and N. gonorrhoeae. Ceftriaxone has an antibacterial spectrum similar to that of cefotaxime but its longer half-life allows for less frequent dosing. Ceftazidime is especially effective against Pseudomonas aeruginosa. Cetixime and cefpodoxime are third-generation cephalosporins that can be administered orally. 

Penicillin V is an orally administered phenoxy-methyl congener of penicillin G having an antibacterial spectrum of activity that is similar to that of penicillin G. Penicillin V is used to treat streptococcal infections when oral therapy is appropriate and desirable. 

Lincomycins are similar to macrolides in biochemical mechanism of action and antibacterial spectrum of activity. They are sulphur-containing antibacterials, first... 

It has an antibacterial spectrum similar to benzyl penicillin but is less active. It is gastric acid stable and effective on oral administration. 

They have broad antibacterial spectrum and are effective against both gram positive and... 

The antibacterial spectrum of cefaclor includes the following organisms Staphylo-... 

Its antibacterial spectrum is similar to that of third generation cephalosporins. It is highly resistant to (3-lactamases. 

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