Soaps Medicated

Bisphenols are composed of two phenolic groups connected by various linkages. Hydroxy halogenated derivatives, such as hexachlorophane (Fig. 10.7D) and triclosan, are the most active microbiologically, but are bacteriostatic at use-concentrations and have little antipseudomonal activity. The use of hexachlorophane is also limited by its serious toxicity. Both hexachlorophane and trichlosan have limited application in medicated soaps and washing creams. 

Deodorants are also targeted to the skin surface to keep microbial growth in check. They slow or prevent rancidification of the secretions of apocrine glands found in and around the axillae (armpits) and the anogenital regions. Medicated soaps also belong in this family. 

In industry, iodine is used for dyes, antiseptics, germicides. X-ray contrast medium, food and feed additives, pharmaceuticals, medical soaps, and photographic film emulsions and as a laboratory catalyst to either speed up or slow down chemical reactions. 

In medicated soaps, substances of medicinal value are added. In some soaps, deodorants are added. Shaving soaps contain glycerol to prevent rapid drying. A gum called, rosin is added while making them. It forms sodium roslnate which lathers well. Laundry soaps contain fillers like sodium roslnate, sodium silicate, borax and sodium carbonate. 

Wait at least 1 hr before using other topical acne preparations containing abrasive or peeling agents, such as medicated soaps, and cosmetics or aftershave containing alcohol... 

The toxicological data for the sulfosuccinate esters are summarized in Table XX. Products of this type in general show low toxicity and low irritation. Eye irritation decreases with increasing EO mole number, approaching the non-irritating level. Further, both skin and eye irritation of AES (Sulfate of PAE) can be significantly weakened when mixed with the sulfosuccinate (Table XX). This effect may suggest their applicabilities in personal care products such as hair or body shampoo, baby soap and medical soap. 

Perfumers must study the perfumes of the products that make up the market also in relation to their positioning. What fragrance types characterize baby soaps and distinguish them from family soaps Do the perfumes of the different brands of medicated soap have something in common What fragrance qualities set the premium priced products apart from the more common ones, heavy duty products from delicate ones The answers to questions such as these define the odor meanings and the odor language that prevail in a market. 

Crude soap curds contain glyccrtil and excess alkali as well as soap but can be purified Iry boiling with water and adding NaCl or KCl to precipitate the pure carboxylate salts. The smooth soap that precipitates is dried, perfumed, and pressed into bars for household use. Dyes are added to make colored soaps, antiseptics are added for medicated soaps, pumice is added for scourirg soaps, and air is blown in for soaps lhat float. Regardless of these extra treatments and regardless of price, though, all soaps are basically the same. 

Dressings, medicated Gums Papers, medicated Soaps... 

Dentifrices Dentifrices are powders, pastes, washes, or medicated soaps used for cleaning the teeth. Dentifrices are usually flavored with aromatic oils, frequently contain soap, almost always some form of chalk, and are applied with a toothbrush. The National Formulary carried official formulas for a liquid dentifrice through its 5th edition (1926) and a powder dentifrice through its 11th edition (1960). ... 

Bisphenols are composed of two phenolic groups connected by various linkages. Triclosan (Fig. 17.7J) is the most widely used. It is bacteriostatic at use-concentrations and has little anti-pseudomonal activity. It has been incorporated into medicated soaps, lotions and solutions and is also included in household products such as plastics and fabrics. There is concern about bacterial resistance developing to triclosan. 

Rhodaquat [Rhone-Poulenc France] Alkyl dimethyl benzyl anunonium chlorides cationic emulsifier, dispersant, bactericide for institutional sin-fectant cleaners, swimming pod dgi-cides, toiletries, medicated soaps dye... 

Between 1850 and 1950 humans were habitually exposed to arsenic in medicine, food, air, and water. Consumer products of the period that contained arsenic included pigments, medicated soaps, embalming solutions, adhesive envelopes, glass, fly-powder, and rat poison. 

GAJ Ayliffe, MF Noy, JR Babb, JG Davies, J Jackson. A comparison of pre-operative bathing with chlorhexidine-detergent and non-medicated soap in the prevention of wound infection. J Hosp Infect 4 237-244, 1983. 

Once the five subjects were admitted to the study, a 14-day pretrial period was observed. During this time, subjects avoided the use of medicated soaps, lotions, shampoos, deodorants, chlorinated water baths, and ultraviolet light tanning beds, as well as skin contact with solvents, acids, and bases. This regimen permitted stabilization of the normal microbial flora populations on the skin. 

Whole hand, fingerpads Poliovirus type 1 (Sabin) Alcohol-containing products, non-medicated soap 71... 

Diisostearyl malate Myristoyl hydrolyzed collagen PEG-75 lanolin surfactant, MDI-based PU foam systems Silicone glycol copolymer surfactant, medicated cleansers Ricinoleamidopropyl betaine surfactant, medicated shampoo Sodium laureth-5 carboxylate surfactant, medicated soaps Sodium laureth-5 carboxylate surfactant, medicated treatments Disodium undecylenamido MEA-sulfosuccinate surfactant, medicinal soaps Potassium cocoate surfactant, metal cleaners Cl 2-15 pareth-9 DEA-lauryl sulfate Magnesium lauryl sulfate PEG-5 oleate PEG-14 oleate... 

After hydrolysis is complete, sodium chloride is added to precipitate the soap as thick curds. The water layer is then drawn off, and glycerol is recovered by vacuum distillation. The crude soap contains sodium chloride, sodium hydroxide, and other impurities that are removed by boiling the curd in water and reprecipitating with more sodium chloride. After several purifications, the soap can be used as an inexpensive industrial soap without further processing. Other treatments transform the crude soap into pH-controlled cosmetic soaps, medicated soaps, and the like. 

Hexachlorophen has been used as a microbicide in cosmetics, medical soaps and detergents, and in textiles with antimicrobial effectiveness. However, because of its toxicity, especially its neurotoxicity and the potential absorption through the skin, the application has been banned worldwide. 

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