Major histocompatibility complex class I proteins

BeneL, Szollosi J, Balazs M, MatyusL, Gaspar R, AmelootM,et al. Major histocompatibility complex class I protein conformation altered by transmembrane potential changes. Cytometry 1997 27 353-357. 

Balow, J. P., Weissman, J. D., and Kearse, K. P. (1995). Unique expression of major histocompatibility complex class I proteins in the absence of glucose trimming and calnexin association./. Biol. Chem. 270, 29025-29029. 

Balow, J.P., Weissman, J.D., and Kearse, K.P. Unique Expression of Major Histocompatibility Complex Class I Proteins in the Absence of Glucose Trimming and Calnexin Association J. Biol. Chem. 1995 270, 29025-19029. 

Bartee, E., et ah, Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. J Virol, 2004, 78(3), 1109-20. 

Bonifaz L. Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, Steinman RM Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CDS4- T cell tolerance. J Exp Med 2002 196 1627-1638. 

Guanine nucleotide binding protein Glutamate receptor Glutathione S-transferases Ion channels involved in congenital long-QT syndrome Major histocompatibility complex class I-B... 

G5. Geraghty, D. E., Koller, B. H., and Orr, H. T. A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment. Proc. Natl. Acad. Sci. 

Olsen A, Wick MJ, Morgelin M, Bjorck L (1998) Curfi, fibrous surface proteins of Escherichia coli, interact with major histocompatibility complex class I molecules. Infect Immun 66 944-949... 

Ishido S, Wang C, Lee BS, Cohen GB, Jung JU (2000b) Downregulation of major histocompatibility complex class I molecules by Kaposi s sarcoma-as.sociated herpesvirus K3 and K5 proteins [In Process Citation]. J Virol 74 5300--5309... 

Sester M, Burgert H-G (1994) Conserved cysteine residues within the E3/19K protein of adenovirus type 2 are essential for binding to major histocompatibility complex antigens. J Virol 68 5423-5432 Sester M, Feuerbach D, Frank R, Preckel T, Gutermann A, Burgert H-G (2000) The amyloid precursorlike protein 2 associates with the major histocompatibility complex class i molecule K. J Biol Chem... 

Golctz TJ, Klimpel KR, Arora N et al. Targeting HIV proteins to the major histocompatibility complex class I processing pathway with a novel gp 120-anthrax toxin fusion protein. Proc Natl Acad Sci USA 1997 94(22) 12059-12064. 

Relatively recent studies show that it would be possible to take advantage of the HSP expression activated by hyperthermia through the application of an AC field. As well as HSP expression, controlled hyperthermia also increases the levels of MHC (major histocompatibility complexes) class I peptides at the surface of tumour cells, whose function is to expose selected protein fragments of cells to cytotoxic T lymphocytes. This causes an immunoresponse, where healthy cells are ignored and cancer cells are attacked. 

Imai Y, Ibata I, Ito D, Ohsawa K, Kohsaka S (1996) A novel gene ibal in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. Biochem Biophys Res Commun 224 855-862 Imitola J, Raddassi K, Park KI, Mueller FJ, Nieto M, Teng YD, Frenkel D, Li J, Sidman RL, Walsh CA, Snyder EY, Khoury SJ (2004) Directed migration of neural stem cells to sites of CN S injury by the stromal cell-derived factor lalpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci USA 101 18117-18122... 

In contrast to the conventional CD4+ and CD8+ T cells of the immune system that recognize specific peptide antigens bonnd to major histocompatibility complex class II or class I antigen presenting proteins, respectively (131-133), invariant natural killer T cells recognize glycolipid antigens presented by histocompatibility complex... 

Group of transmembrane proteins engaged in the presentation of small peptide fragments to T-cells. Two classes of Major histocompatibility complex (MHC) molecules exist both of which are encoded by a highly polymorphic gene cluster. MHC class I and class II proteins present peptide fragments to CD8+ and CD4+ T-cells, respectively. The human MHC is also known as HLA, the murine MHC as H-2 complex. 

Tsomides, T.J., Walker, B.D., and Eisen, H.N. (1991) An optimal viral peptide recognized by CD8+T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein. Proc. Natl. Acad. Sci. USA 88, 11276-11280. 

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