Activity expressions

The operational model allows simulation of cellular response from receptor activation. In some cases, there may be cooperative effects in the stimulus-response cascades translating activation of receptor to tissue response. This can cause the resulting concentration-response curve to have a Hill coefficient different from unity. In general, there is a standard method for doing this namely, reexpressing the receptor occupancy and/or activation expression (defined by the particular molecular model of receptor function) in terms of the operational model with Hill coefficient not equal to unity. The operational model utilizes the concentration of response-producing receptor as the substrate for a Michaelis-Menten type of reaction, given as... 

The Flory-Huggins activity expression for solvent in a solvent(l)/polymer(2) solution is... 

Table I. Activity Expressed as Percent of Dose per Gram...

Table II. Activity Expressed as Percent of Dose per Gram (%/gram) in Various Tissues of Rats 3, 7, and 21 Days Following a Single Oral Dose of TCDD- C ...

Figure 3. PME isoform patterns in cell wall extracts fiom active and resting cells, a cell wall extracts from successive segments (A, B, C and D) sectioned along mui bean hypocotyb and exhibiting decreasing elongation rates a, and y m c the main PME isoforms present in the extracts, tteir pi are respectively around 7.5, S.5 and above 9.1. b cell wall extracts obtained from poplar cambium and inner bark tissues during cambial active (may) and rest (december and march) periods 1, 2 and 3 represent the activity of 3 groups of PME isoforms with pi around 5-6, 7.5 and above 9.1. Activities expressed as percent of total PME activity present in each extract.

Figure 1. Separation profile on Sephacryl SlOO column of extracellular PG. 2.7 ml fractions were analyst for protein ( ) and reducing sugars released (A). Peaks I, II, III and IV correspond to PG activity expressed as pmol galacturonic acid released min V...

Pectinesterase activity expressed as a unit corresponding to the microequivalent of ester bonds of pectin molecule, which were hydrolyzed during 1 min. at 45 °C and pH 5.0 under the conditions, which were optimum for these enzymes. Endopolygalacturonase and exopolygalacturonase activities were determined using a technique determined by Ufshitz [8]. Activity of pectintranseliminase was determined by procedure (lOJ. 

The transformation of cyclopentanol-cyclohexanone mixture was carried out on aluminas, and compared with a basic (MgO) and acidic (HMOR zeolite, Si/Al = 80) catalysts. Figure 2 shows the activities, expressed as mmol.h 1.m 2, for the two reactions, for the different catalysts. 

Keratan sulfate (102-104), hen ovomucin (105), rat gastric mucins (106), porcine thyroglobulin (107) Recombinant tissue plasminogen activator expressed in mouse epithelial cells (108)... 

There are essentially three groups of proteins actively expressed by neutrophils ... 

Aoyama Y, Horiuchi T, Yoshida Y. 1996a. Lanosterol 14-demethylase activity expressed in rat brain microsomes. J Biochem (Tokyo) 120 982-986. 

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