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Class I MHC-restricted CTL

Gavin MA, Gilbert MJ, Ridell SR, Greenberg RD, Bevan MJ (1993) Alkali hydrolysis of recombinant proteins allows for the rapid identification of class I MHC-restricted CTL epitopes, J Immunol 151 3971-2894. [Pg.378]

Haicheur N, Bismuth E, Bosset S et al. The B subunit of Shiga toxin fused to a tumor antigen elicits CTL and targets dendritic cells to allow MHC class I-restricted presentation of peptides derived from exogenous antigens. J Immunol 2000 165(6) 3301-3308. [Pg.18]

Lysis of tumor cells by CD8 CTLs has been demonstrated to be an important effector mechanism of tumor defense and rejection. They destroy target cells by recognizing epitope peptides in a MHC class I restricted manner. In certain murine tumor systems, epitope peptides recognized by CD8 CTLs have been identified, and the feasibility of vaccination with those peptides either for the prevention or the treatment of tumors has been demonstrated. [Pg.331]

See other pages where Class I MHC-restricted CTL is mentioned: [Pg.250]    [Pg.324]    [Pg.324]    [Pg.327]    [Pg.250]    [Pg.324]    [Pg.324]    [Pg.327]    [Pg.327]    [Pg.247]    [Pg.245]    [Pg.60]    [Pg.773]    [Pg.773]    [Pg.2688]    [Pg.659]    [Pg.20]    [Pg.20]    [Pg.358]    [Pg.157]    [Pg.133]    [Pg.376]    [Pg.28]    [Pg.29]    [Pg.245]    [Pg.254]    [Pg.332]   
See also in sourсe #XX -- [ Pg.324 , Pg.327 , Pg.332 ]



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CTL

CTLs

Class I MHC

MHC

MHC class

MHC restriction

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