Macrophage cell line

Fiirvonen M.-R., Nevalainen, A., N, Monkkonen, J., and Savolainen, K. (1997). Streptomyces spores trom mouldy houses induce nitric acid, TTNFa and 11,-6 secretion from R.AW264.7 macrophage cell line without causing subsequent cell death. Environ. Toxicol. Pharmacol. 4, 57-63. 

McDevitt, TM, Tchao, R, Harrison, EH, and Morel, DW, 2005. Carotenoids normally present in serum inhibit proliferation and induce differentiation of a human monocyte/macrophage cell line (U937). J Nutr 135, 160-164. 

Sakata K, Hirose Y, Qiao Z, Tanaka T and Mori H. 2003. Inhibition of inducible isoforms of cyclooxygenase and nitric oxide synthase by flavonoid hesperidin in mouse macrophage cell line. Cancer Lett 199(2)439-145. 

Ichikawa, D. et al., Effect of various catechins on the IL-12p40 production by murine peritoneal macrophages and a macrophage cell line, J774.1, Biol Pharm Bull, 27, 1353, 2004. 

Z. Z., Morris, S. M., )r., Coinduction of nitric oxide synthase and argininosuccinate synthetase in a murine macrophage cell line. Implications for regulation of nitric oxide production,/. Biol. Chem. 269 (1994), p. 1257-12561... 

Kobuchi H, Droy-Lefaix MT, Christen Y, Packer L. (1997). Ginkgo biloba extract (EGb 761) inhibitory effect on nitric oxide production in the macrophage cell line RAW 264.7. Biochem Pharmacol. 53(6) 897-903. 

Andersen O. 1983. Effects of coal combustion products and metal compounds on sister chromatid exchange (SCE) in a macrophage cell line. Environ Health Perspect 47 239-253. 

Tumor necrosis factor inhibition. Ethanol (95%) extract of the rhizome, in cell culture at a concentration of 100 pg/mL, was inactive on macrophage cell line RAW 264.7 vs EPS induction of TNF-az° zp Tumor promotion inhibition. Ethyl acetate and methanol extracts of the dried rhizome, in cell culture at a concentration of 50 pg/mL, produced weak activity on G3H/ lOTl/2 cells vs tetradecanoyl phorbol acetate-induced acetate phospholipid synthesis. The hexane extract was inactiveZ . Ethanol (95%) and petroleum ether extracts of the dried rhizome, in cell culture at a concentration of 160 and 80 pg/mL, re-... 

Analysis by SDS-polyacrylamide gel electrophoresis of purified NOS from isolated HC from rats injected with killed Corynebacterium parvum (H), and from the murine macrophage cell line RAW 264-7 (M) (courtesy of D. Stuehr, The Cleveland Clinic, Cleveland, OH) which was exposed to LPS and IFNy. Crude cytosols were separated using ion exchange and affinity 2 5 -ADP Sepharose chromatography. Last step by gel filtration is equivalent to separation by molecular weight. 

Previous studies on the effects of N=0 production on the alloimmune response utilized bulk populations of responder and stimulator cells. In order to more clearly define the circumstances that induce -N=0 synthesis in allogeneic macrophage-lymphocyte cocultures, mouse splenocyte populations were depleted of accessory cells (>90% Thy 1.2+) and cultured with mitomycin-C-treated macrophage cell lines, as the alloantigen presenting cells. The P388D1 (H2 ) and RAW 264.7 (H2 ) macrophage lines were selected because... 

CTM = cytotoxic activity against mouse macrophage cell line (RAW 264.7) [167] ... 

Nham, S. U., and Fuller, G. M. (1986). Effect of fibrinogen degradation products on production of hepatocyte stimulating factor by a macrophage cell line (P388D1). Thromb. Res. 44, 467-475. 

Recently, Tan et al. (Tan et ah, 2007) demonstrated that activation of (32-adrenoreceptors in the macrophage cell line (RAW264.7) in the absence of inflammatory stimulus increased the transcription and protein synthesis of IL-1 (3 and IL-6. This increase was not reduced by neither a PKA nor a NF-kB inhibitor, but was dependent on p38 and p42/44 MAPK activation, which in turn, activated activating transcription factor (ATF)l and ATF2. 

Brown SW, Meyers RT, Brennan KM, Rumble JM, Narasimhachari N, Perozzi EF, Ryan JJ, Stewart JK, Fischer-Stenger K (2003) Catecholamines in a macrophage cell line. J. 

Channon, J. Y., and Leslie, C. C. 1990. A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7. J. Biol Chem. 265 5409-5413. 

Fig. 14.2 Cytokine responses to a human macrophage cell line (MonoMac 6) exposed to liposomal formulations of GLA. Liposomes contained the lipids indicated on the x-axis, cholesterol, and GLA. Adjuvant concentration was serially diluted by factors of 5 for each group, from left to right. LPS is the positive control. Variations in adjuvant activity are apparent depending on the phospholipid composition of the liposomes...

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