Lymphomas leukemia/lymphoma

Cancer treatment is a multimodality treatment, i.e., surgery is combined with radiotherapy and antineoplastic chemotherapy. The latter treatment mode is used mainly for cancers which have disseminated. Different forms of cancer differ in their sensitivity to chemotherapy with antineoplastic agents. The most responsive include lymphomas, leukemias, choriocarcinoma and testicular carcinoma, while solid tumors such as colorectal, pancreatic and squamous cell bronchial carcinomas generally show a poor response. The clinical use of antineoplastic agents is characterized by the following principles. [Pg.157]

Hodgkin s disease, lymphocytic lymphoma, histiocytic lymphoma, mycosis fungoides, testicular cancer, Kaposi s sarcoma, breast cancer Acute leukemia, combination therapy for various cancers... [Pg.586]

Precursor B-cell neoplasm Precursor B-lymphoblastic leukemia/lymphoma Mature (peripheral) B-cell neoplasms B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma... [Pg.1374]

AduItT-cell lymphoma/leukemia (HTLV1 positive)... [Pg.1374]

Lymphomas not included in Working Formulation mycosis fungoides, mantle cell lymphoma, monocytoid B-cell lymphoma, mucosa-associated lymphoid tissue (MALT), anaplastic large cell lymphoma, angiocentric lymphoma, angioimmunoblastic lymphadenopathy (AILD), Castleman s disease, adult T-cell leukemia/lymphoma. [Pg.1376]

Ishii E, Kawasaki H, Isoyama K, et al. Recent advances in the treatment of infant acute myeloid leukemia. Leukemia Lymphoma 2003 44 741-748. [Pg.1413]

Ishida T, Iida S, Akatsuka Y, et al. The CC chemokine receptor 4 as a novel specific molecular target for immunotherapy in adult T-cell leukemia/lymphoma. Clin Cancer Res 2004 10 7529-7539. [Pg.350]

Conditions with infiltration of bone marrow Lymphoma Leukemia Myelofibrosis Carcinoma... [Pg.377]

Leukemia, lymphoma, Hodgkin s disease, or multiple myeloma / Generalized malignancy / Chronic renal failure of nephritic syndrome / Patients receiving immunosuppressive therapy / Organ or bone marrow transplant recipients... [Pg.586]

Keywords Tyrphostins, Protein tyrosine, Kinases, JAK-2 EGF, PDGF BCR-ABL, Psoriasis, Papilloma, Restenosis, Leukemia, Lymphoma... [Pg.2]

Isomaki, H.A., Hakulinen, T., and Joutsenlahti, U., Excess risk of lymphomas, leukemias and myeloma in patients with rheumatoid arthritis, J. Chronic Dis., 31, 691, 1978. [Pg.138]

Vaccines Yes. Wyeth Vaccine, called VIG or vaccinia immune globulin, one dose by scarification. (Pre- and post-exposure vaccination recommended if greater than three years passed since last vaccine.) Persons who are pregnant, have clinical immunosuppression (such as persons who have undergone heart and other transplant operations and take medicines to control rejection of their new, transplanted organ), eczema, and/or leukemia/ lymphoma would be contraindicated for such vaccine. As one example, the fatality rate for immunosuppressed persons taking such vaccine could be as high as 75 percent or more. [Pg.173]

C2. Cossman, J., Zehnbauer, B., Garrett, C. T., Smith, L. J., and Hanson, L. O., Gene rearrangements in the diagnosis of lymphoma/leukemia Guidelines for use based on multi-institutional study. Amer. J. Clin. Pathol. 95, 347-354 (1991). [Pg.70]

Jaffrezou, . P., Bettaieb, A., Levade, T., and Laurent, G., 1998, Antitumor agent-induced apoptosis in myeloid leukemia cells a controlled suicide. Leukemia Lymphoma 29 453-463... [Pg.281]

Balasubramanian, S., Ramos, J., Luo, W, Sirisawad, M., Verner, E. and Buggy, J.J. (2008) A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas. Leukemia, 22, 1026-1034. [Pg.133]

Doxorubicin and dannorabicin are antibiotics made from microorganisms of the family Streptomyces peucetius. The stmcture of these anthracyclines contains an aminosaccarhide residue daunozamine attached to a naphthacenequinone nucleus. Doxorubicin differs from daunorubicin in the presence of a hydroxyl gronp at C14. A nnmber of mechanisms have been suggested in which anthracyclines exhibit cytotoxicity. They canse DNA to denature, are involved in oxidation-rednction reactions, chelate bivalent cations and react with cell membranes, changing their fnnction. They are used for severe leukemia, lymphoma, breast and ovarian cancer, and other solid tumors. [Pg.403]

Etoposide and teniposide are synthetic derivatives of the extract of the American mandragora plant (May Apple). The mechanism of their action has not been completely explained however, they act on the enzyme topoisomerase II, which disturbs the twisting of DNA. In addition, they inhibit DNA and RNA synthesis, as well as transport of nucleotides to cells. Cytotoxic action on normal cells is observed only in very high doses. These drugs exhibit significant activity in lymphomas, leukemia, Kaposi s sarcomas, and in testicular cancer. [Pg.406]

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