Lymphadenopathy angioimmunoblastic

Lymphomas not included in Working Formulation mycosis fungoides, mantle cell lymphoma, monocytoid B-cell lymphoma, mucosa-associated lymphoid tissue (MALT), anaplastic large cell lymphoma, angiocentric lymphoma, angioimmunoblastic lymphadenopathy (AILD), Castleman s disease, adult T-cell leukemia/lymphoma. 

Pay S, Dine A, Simsek I, Can C, Erdem H. Sulfasalazine-induced angioimmunoblastic lymphadenopathy developing in a patient with juvenile chronic arthritis. Rheumatol Int 2000 20(l) 25-7. 

Angioimmunoblastic lymphadenopathy is a rare disorder characterized by generalized lymphadenopathy, fever, hepatosplenomegaly, immune hemolytic anemia, and polyclonal hypergammaglobulinemia. Biopsy-proven angioimmunoblastic lymphadenopathy has been reported in a 79-year-old man who had received ciprofloxacin (60). 

Angioimmunoblastic lymphadenopathy, systemic lupus erythematosus, polymyositis, and serum sickness have been noted in individual cases (SED-13,144) (50,51). 

Anagnostopoulos I, Hummel M, Firm T, et al. Heterogeneous Epstein-Barr virus infection patterns in peripheral T-cell lymphoma of angioimmunoblastic lymphadenopathy type. Blood. 1992 80(7) 1804-1812. 

Frizzera G, Moran EM, Rappaport H (1974) Angioimmunoblastic lymphadenopathy with dysproteinemia. Lancet 1 1070... 

Pruzanski W, Sutton DM, Pantalony D (1976) Angioimmunoblastic lymphadenopathy An immunochemical study. Clin Immunol Immunopathol 6 62 Pullen H, Wright N, Murdoch JM (1967) Hypersensitivity reactions to antibacterial drugs in infectious mononucleosis. Lancet 2 1176... 

Angioimmunoblastic lymphadenopathy (AIBL) can involve the lung in the form of diffuse interstitial infiltrates. Typically, there is little difficulty in distinguishing AIBL from LIP since AIBL has a distinctive set of clinical features, including generalized lymphadenopathy, hepatosplenomegaly, Coombs-positive hemolytic anemia, and skin rash. Microscopically, AIBL is polymorphous but includes numerous atypical immunoblasts as well as lymphocytes and plasma cells. The cellular infiltrate also predominantly involves lymphatic routes (around airways and vessels), rather than the interstitial compartment, as in the case of LIP (69). 

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