Lymphogranuloma venereum

The sulfas also remain clinically useful in the treatment of chancroid, lymphogranuloma venereum, trachoma, inclusion conjunctivitis, and the fungus-related nocardiosis (7). In combination with pyrimethamine, they are recommended for toxoplasmosis (8) and have been used for chloroquine-resistant falciparium malaria (4,9). There has also been some use of sulfas for the prophylaxis of rheumatic fever. The sulfone, dapsone, remains an accepted treatment for all forms of leprosy (4). 

Irritable bowel syndrome, diverticulitis, upper and lower GI tract diseases, hemorrhoids, anal fissures, ulcerative proctitis, tumors, hernia, volvulus of the bowel, syphilis, tuberculosis, lymphogranuloma venereum, Hirschsprung s disease. 

Lymphogranuloma venereum 100 mg twice daily for at least 21 days. 

Lymphogranuloma venereum. Three weeks of either doxycycline 2 x 100 mg daily or erythromycin 4 X 500 mg daily are the therapies of choice for this condition. 

Respiratory, skin, and soft-tissue infections UTIs pelvic inflammatory disease (PID) brucellosis trachoma Rocky Mountain spotted fever typhus Q fever lickettsia severe acne (Adoxa) smallpox psittacosis ornithosis granuloma inguinale lymphogranuloma venereum intestinal amebiasis (adjunctive treatment) prevention of rheumatic fever ... 

Chlamydia causing lymphogranuloma venereum, psittacosis, trachoma and inclusion conjunctivitis. 

Chlamydia trachomatis Blennorrhea lymphogranuloma venereum nonspecific urethritis trachoma Doxycycline or azithromycin Levofloxacin or ofloxacin... 

Lymphogranuloma venereum an infectious venereal disease marked progressively by lymph node hypertrophy, lymphatic obstruction, and elephantiasis of external genitalia. 

The spectrum of sexually transmitted diseases (STDs) includes the classic venereal diseases—gonorrhea, syphilis, chancroid, lymphogranuloma venereum, and granuloma inguinale—as well as a variety of other pathogens known to he spread hy sexual contact (Table 46-1). Common clinical syndromes associated with STDs are listed in Table 46-2. The most current information on epidemiology, diagnosis, and treatment of STDs provided by the Centers for Disease Control and Prevention (CDC) can be found at http //www.cdc.gov. 

Chlamydiae are obligate intracellular parasites that depend on the host cell to carry out metabolic biosynthe-sis.The genus includes two major species C. trachomatis, which causes disease in humans, and Chlamydia psittaci, which infects primarily nonhumans. The many different serotypes cause a wide spectrum of disease states, including inclusion conjunctivitis, trachoma, lymphogranuloma venereum, and cervicitis or urethritis. 

This chapter is a review of the antimicrobial susceptibilities of the causative organisms and the treatment of the sexually transmitted infections most prevalent in North America and Western Europe, gonorrhea, nongonococcal urethritis, genital herpes virus infections, and trichomoniasis. Because of their relative rarity or because no important advances in therapy have been made in the past decade, syphilis, lymphogranuloma venereum, chancroid, and granuloma inguinale are not considered. 

Jones RB, Batteiger BE. Chlamydia trachomatis (trachoma, perinatal infections, lymphogranuloma venereum, and other genital infections). In Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases, 5th ed. New York, Churchill-Livingstone, 2000 1989-2004. 

McMillan A, Ballard RC. Non-specific genital tract infection and chlamydial infection, including lymphogranuloma venereum. In McMillan A, Young H, Ogilvie MM, Scott GR, eds. Clinical Practice in Sexually Transmissible Infections. London, Saunders, 2002 281-312. 

Lymphogranuloma venereum—Inflammation of the lymph nodes caused by Chlamydia trachomatis resulting in destruction and scarring of tissue. 

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