Lobes

Similarly, the focusing capability of an array is the strongest focused beam which can be steered. The simplest way to evaluate it is to test a theoretical focusing time delay law, in the near-field and in the natural direction of propagation of the array. The beam pattern characteristics depth, lateral size and length of the focal spot must be found consistent with modelling and no lobe must appear above a predetermined level. 

The spectral frequency range covered by the central lobe of this sinc fiinction increases as the piilselength decreases. For a spectrum to be undistorted it should really be confined to the middle portion of this central lobe (figure B 1.12.2). There are a number of examples in the literature of solid-state NMR where the resonances are in fact broader than the central lobe so that the spectrum reported is only effectively providing infonnation about the RF-irradiation envelope, not the shape of the signal from the sample itself... 

A sine-shape has side lobes which impair the excitation of a distinct slice. Other pulse envelopes are therefore more commonly used. Ideally, one would like a rectangular excitation profile which results from a sine-shaped pulse with an infinite number of side lobes. In practice, a finite pulse duration is required and therefore the pulse has to be truncated, which causes oscillations in the excitation profile. Another frequently used pulse envelope is a Gaussian frmction ... 

Freyhardt C C, Tsapatsis M, Lobe R F, Balkus Jr K J and Davis M E 1996 A high-silica zeolite with a 14-tetrahedral-atom pore opening Nature 381 295-8... 

THE cvcLOBUTADENE-TETRAHEDRANE SYSTEM. A related reaction is the photoisomerization of cyclobutadiene (CBD). It was found that unsubstituted CBD does not react in an argon matrix upon irradiation, while the tri-butyl substituted derivative forms the corresponding tetrahedrane [86,87]. These results may be understood on the basis of a conical intersection enclosed by the loop shown in Figure 37. The analogy with the butadiene loop (Fig. 13) is obvious. The two CBDs and the biradical shown in the figure are the three anchors in this system. With small substituents, the two lobes containing the lone electrons can be far... 

Fig. 1. Superposition of three crystal structures of cAMP-dependent protein kinase that show the protein in a closed conformation (straight line), in an intermediate conformation (dashed line), and in an open conformation (broken line). The structures were superimposed on the large lobe. In three locations, arrows identify corresponding amino acid positions in the small lobe.

The effective moment of inertia / and the friction coefficient / could easily be estimated. The force constant k associated with the relative motion of the lobes was determined from an empirical energy function. To do so, the molecule was opened in a step-wise fashion by manipulating the hinge region and each resulting structure was energy minimized. Then, the interaction energy between the two domains was measured, and plotted versus 0. 

The catalytic subunit then catalyzes the direct transfer of the 7-phosphate of ATP (visible as small beads at the end of ATP) to its peptide substrate. Catalysis takes place in the cleft between the two domains. Mutual orientation and position of these two lobes can be classified as either closed or open, for a review of the structures and function see e.g. [36]. The presented structure shows a closed conformation. Both the apoenzyme and the binary complex of the porcine C-subunit with di-iodinated inhibitor peptide represent the crystal structure in an open conformation [37] resulting from an overall rotation of the small lobe relative to the large lobe. 

Figure 7-23. The polarizing effect ofd-orfeitals. a) The energy of the. t-MO can be lowered slightly by shifting the centers of the AOs slightly towards the center of the bond, b) The lobes ca n be directed towards each other by mixing soine d-character into the p-orbitals. The effect is exaggerated for clarity.

Conservation of orbital symmetry is a general principle that requires orbitals of the same phase (sign) to match up in a chemical reaction. For example, if terminal orbitals are to combine with one another in a cyclixation reaction as in pattern. A, they must rotate in the same dii ection (conrotatory ovei lap). but if they combine according to pattern H. they must rotate in opposite directions (disrotatory). In each case, rotation takes place so that overlap is between lobes of the it orbitals that are of the same sign. 

Other methods are also used to contrast the regions of an orbital where the signs of the wave function are differ ent Some mark one lobe of a p orbital + and the other — Others shade one lobe and leave the other blank When this level of detail isn t necessary no differentiation IS made between the two lobes... 

FIGURE 2 9 Each half filled sp orbital overlaps with a half filled hydrogen Is or bital along a line between them giving a tetrahedral arrangement of four ct bonds Only the major lobe of each sp orbital is shown Each orbital contains a smaller back lobe which has been omitted for clarity... 

Because each carbon m acetylene is bonded to two other atoms the orbital hybridization model requires each carbon to have two equivalent orbitals available for CT bonds as outlined m Figure 2 19 According to this model the carbon 2s orbital and one of Its 2p orbitals combine to generate two sp hybrid orbitals each of which has 50% s character and 50% p character These two sp orbitals share a common axis but their major lobes are oriented at an angle of 180° to each other Two of the original 2p orbitals remain unhybridized... 

AO is antisymmetric to this reflection. In fact, we can easily see that any overlap between 2s and the positive lobe of 2p is exactly cancelled by that involving the negative lobe. 

Fig. 4. Operating sequence for a two-lobed rotary gas flow meter where the shaded area represents the flowing fluid.

The posterior lobe of the pituitary, ie, the neurohypophysis, is under direct nervous control (1), unlike most other endocrine organs. The hormones stored in this gland are formed in hypothalamic nerve cells but pass through nerve stalks into the posterior pituitary. As early as 1895 it was found that pituitrin [50-57-7] an extract of the posterior lobe, raises blood pressure when injected (2), and that Pitocin [50-56-6] (Parke-Davis) causes contractions of smooth muscle, especially in the utems (3). Isolation of the active materials involved in these extracts is the result of work from several laboratories. Several highly active posterior pituitary extracts have been discovered (4), and it has been deterrnined that their biological activities result from peptide hormones, ie, low molecular weight substances not covalendy linked to proteins (qv) (5). 

Melatonin [73-31-4] C 2H N202 (31) has marked effects on circadian rhythm (11). Novel ligands for melatonin receptors such as (32) (12), C2yH2gN202, have affinities in the range of 10 Af, and have potential use as therapeutic agents in the treatment of the sleep disorders associated with jet lag. Such agents may also be usehil in the treatment of seasonal affective disorder (SAD), the depression associated with the winter months. Histamine (see Histamine and histamine antagonists), adenosine (see Nucleic acids), and neuropeptides such as corticotropin-like intermediate lobe peptide (CLIP) and vasoactive intestinal polypeptide (VIP) have also been reported to have sedative—hypnotic activities (7). 

Positive Pumps. Positive pumps employed by the food industry have a rotating cavity between two lobes, two gears that rotate in opposite directions, or a crescent or stationary cavity and a rotor. Rotary positive pumps operate at relatively low speed. Fluid enters the cavity by gravity flow or from a centrifugal pump. The positive pump also may use a reciprocating cavity, and may be a plunger or piston pump. These pumps are not truly positive with respect to displacement, but are used for metering product flow. 

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