Liver acute hemorrhage

The richest dietary sources of total iron are organ meats (liver and kidney), egg yolk, dried legumes, com, molasses and parsley. Liver is particularly valuable because of the high absorbability of its iron. However, only about 10% of dietary iron is absorbed. Iron deficiency anemia can be treated with soluble iron(II) compounds providing 200 mg in three or four daily divided doses. Oral iron(II) sulfate is the least expensive and is in wide use. Ascorbic acid increases the absorption efficiency of iron(II) sulfate. Parenteral administration of iron is used when oral iron is ineffective. Iron-dextran, a colloid formed from iron(III) chloride and an alkali-modified dextran, is one of several preparations available which has found extensive clinical use. It contains up to 28% Fe by weight and has a structural similarity to ferritin. Transfusion therapy may also be used in severe chronic anemia or acute hemorrhage. 

Indications Blood heat reckless movement, replete fire in the liver and stomach. Hematemesis, hemoptysis, epistaxis, pulmonary tuberculosis, bronchiectasis, acute hemorrhagic esophagitis or gastritis, peptic ulcer bleeding, hemorrhagic febrile diseases, and functional uterine bleeding... 

In emergency cases, such as acute hemorrhage within the liver (e.g., in a preexisting tumor, after liver biopsy, or after blunt abdominal trauma), acute vascular occlusion, or inflammatory lesions such as abscesses, MDCT... 

The influence of sodium chloride on water retention is illustrated in many medical conditions. Diets low in salt assist in the control of edema in acute hemorrhagic nephritis, nephrosis, congestive heart failure, hypo-proteinemia, and cirrhosis of the liver. Recently diets very low in salt (sodium content, 200 to 300 mg.) have been used in the therapy of hypertension, with beneficial results in a percentage of cases. The role of sodium in disease states has been reviewed recently by Danowski. ... 

Bald NC, Semelka RC, Noone TC, et al (1999) Acute and subacute liver-related hemorrhage MRI findings. Magn Reson Imaging 17 207-211... 

Fig. 27.8. Axial CT scan of the liver obtained 24 h after radiofrequency treatment. The black arrow points to new high density fluid adjacent to the liver, consistent with acute hemorrhage...

The liver is sensitive to hexachloroethane following both acute and longer term exposure scenarios. Evidence of effects on the liver include increased weight and centrilobular necrosis in rats and rabbits and increased serum levels of liver enzymes in sheep. There can also be fatty degeneration of the tissues and hemorrhage when damage is severe. 

The second case is that of a 34-year-old woman who had been exposed to vapors of 1,4-dichlorobenzene at work and became acutely ill with nausea and vomiting, and was hospitalized with hemorrhage from the gastrointestinal tract (Cotter 1953). The physical and chemical findings led to the diagnosis of subacute yellow atrophy and cirrhosis of the liver from 1,4-dichlorobenzene exposure. No further information was located. 

Gemtuzumab [Mylotarg] Acute myeloid leukemia Hemorrhage liver toxicity infection joint pain lung toxicity Gl distress [nausea, vomiting, diarrhea] others... 

Qualitative biomarkers of acute oral exposure that are shared with other toxic compounds include a variety of electrocardiogram alterations. Postmortem biomarkers include fatty hepatic degeneration, pulmonary edema and/or congestion, widespread internal hemorrhaging, widespread intracellular fatty deposits, various myocardial damage, hepatic necrosis, hepatic fibrosis, and increased liver weight (see Section 2.2 for more detail). 

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