Leukine

Karras J.G., Maier M.A., Lu T, Watt A., Manoharan M. Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine inter-leukin-5 receptor-alpha chain. Biochemistry 2001 40 7853-7859. [Pg.173]

Leukine GMCSF Eosinophil, SQ or IV or round to Low-grade fever induction chemotherapy in... [Pg.1471]

Leukine Sargramostim (GM-CSF) Immunex Autologous bone marrow transplantation, neutropenia resulting from chemotherapy, peripheral blood progenitor cell mobilization, and transplantation... [Pg.694]

Leukine(sargramostim, Lyophile for IV infusion. 2-8°C do not freeze or shake Each vial 250 or 500 mg... [Pg.709]

The yeast Hansenula polymorpha serves as the production system for a recombinant hepatitis B vaccine (Berna Biotech AG [8] and yeast is also used to produce granulocyte-macrophage colony stimulating factor (GM-CSF), marketed as Leukine by Schering AG. [Pg.268]

EPO and colony-stimulating factors Epogen/Procrit, Leukine, Neorecormon, Nespo/Aranesp... [Pg.32]

Leukine Granulocyte macrophage CSF (GM-CSF) Bone marrow transplantation 10... [Pg.111]

Leukine (sargramostim, GM-CSF) Autologous bone marrow transplantation Neutrophil recovery after bone marrow transplantation Berlex Labs... [Pg.266]

Pettit D.K., JochheimC.M., NighlingerN.S., Willans F.L., Leach K.J., and Gombotz W.R. (2001), EDTA prevents N-terminal proteolysis in a pre-filled syringe formulation of Leukine , ACS National Meeting, San Diego, CA. [Pg.278]

Whittaker L, Niu N, Temann UA, Stoddard A, Flavell RA, Ray A, et al Interleukin-13 mediates a fundamental pathway for airway epithehal mucus induced by CD4 T cells and inter-leukin-9. Am J Respir Cell Mol Biol 2002 27 593-602. [Pg.172]

Leckie MJ, ten Brinke A, Khan J, Diamant Z, O Connor BJ, Walls CM, Mathur AK, Cowley HC, Chung KF, Djukanovic R, Hansel TT, Holgate ST, Sterk PJ, Barnes PJ Effects of an inter-leukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response. Lancet 2000 356 2144-2148. [Pg.188]

Idzko M, Panther E, Bremer HC, Sorichter S, Luttmann W, Virchow CJ Jr, Di Virgilio F, Herouy Y, Norgauer J, Ferrari D Stimulation of P2 purinergic receptors induces the release of eosiuophil cationic protein and inter-leukin-8 from human eosinophils. Br J Pharmacol 2003 138 1244-1250. [Pg.199]

Tarzi M, Klunker S, Texier C, Verhoef A, Stapel SO, Akdis CA, Maillere B, Kay AB, Larche M Induction of inter-leukin-10 and suppressor of cytokine signalling-3 gene expression foUowing peptide immunotherapy. Clin Exp AUergy 2006 36 465-474. [Pg.209]

Autologous bone marrow transplantation involves initial removal of some marrow from the patient, its storage in liquid nitrogen, followed by its re-introduction into the patient subsequent to chemo- or radiotherapy. Leukine is the tradename given to a recombinant human GM-CSF preparation produced in engineered S. cerevisiae (Table 6.4). [Pg.263]

Leukine (rGM-CSF, differs from the native human protein by one amino acid. Leu 23. Produced in S. cerevisiae)... [Pg.502]

Gutierrez-Ortega, A., Sandoval-Montes, C., de Olivera-Flores, T.J., Santos-Argumedo, L., Gomez-Lim, M.A. (2005). Expression of functional inter-leukin-12 from mouse in transgenic tomato plants. Transgenic Res. 14(6) 877-885. [Pg.51]

Magnuson, N.S., Linzmaier, P.M., Reeves, R., An, G., HayGlass, K., and Lee, J.M. (1998). Secretion of biologically active human interleukin-2 and inter-leukin-4 from genetically modified tobacco cells in suspension culture. Protein Exp. Purif. 13(1) 45-52. [Pg.144]

Tmmunex became a part of Amgen in 2002 and the right to market Leukine was transferred to another company as a part of the requirement by US Federal Trade Commission. [Pg.27]

An indirect consequence of antibody formation against a therapeutic protein is inhibition of endogenous protein and its functions. For example, if antibody to inter-leukin-2, a T-cell growth factor, is elicited... [Pg.114]

Granulocyte-macrophage colony-stimulating factor GM-CSF Leukine, sagramostatin Macrophage colony-stimulating factor M-CSF colony-stimulating factor-1 (CSF-1)... [Pg.130]

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