Genetically modified tobacco

Magnnson, N.S., Linzmaier, P.M., Gao, J.W., Reeves, R., An, G., and Lee, J.M. (1996). Enhanced recovery of a secreted mammalian protein from suspension culture of genetically modified tobacco cells. Protein Exp. Purif. 7 220-228. 

Therefore, the production of foreign proteins from genetically modified tobacco cells can be accomplished. 

J3. Johnson, K. S., and Felton, G. W., Plant phenolics as dietary antioxidants for herbivorous insects A test with genetically modified tobacco. J. Chem. Ecol. 27,2579-2597 (2001). 

Magnuson, N.S. Linzmaier, P.M. Reeves, R. An, G. HaGlass, K. Lee, J. Secretion of biologically active human interleukin-2 and interleukin-4 from genetically modified tobacco cells in suspension culture. Protein Express Purif 1998, 13, 45-52. 

Liu F, Lee JM (1999) Effect of culture conditions on monoclonal antibody production from genetically modified tobacco suspension cultures. Biotechnol Bioprocess Eng 4 259-263. 

Plant platforms for producing PHA have been recently reviewed [176, 177]. An example of high yields is reported in a genetically modified tobacco plant Nicotiana tabacum) transformed to contain Acinetobacter sp., genes. The modified tobacco produced between 17 and 19% (w/w) polyhydroxybutyrate (PHB) in leaf tissues [178]. 

Genetically modified, insect resistant cotton expressing the Cry 1 Ac protein provides protection against several of the major insect pests in U.S. cotton the pink bollworm, cotton bollworm, and tobacco budworm. Given their strongly resembling appearance. 

However, there has been some progress with green and ethical funds. These seek to exclude firms involved in areas such as arms, nuclear power, tobacco, biotechnology and, more recently, genetically modified foods. According to the Mail on Sunday, 2.5 billion was invested in the UK in ethical funds and trusts by mid-1999. The... 

For more than 10 years, new synthesis techniques have been under study at an industrial level. Metabolix (USA) has developed a means of PH A production using genetically modified cultures. In 2010, that company announced that it had performed conclusive tests on PHA production on modified tobacco plants, stemming from green biotechnologies. 

A recent study described MRI characterization of lung tumors in mice (51). Aimed at understanding the genetic modifiers of lung cancer induction and therapy, MRI was used to detect small tumors in the lungs of mice treated with the tobacco-specific carcinogen, benzo(a)pyrene. Figure 5.2 shows representative... 

Previously, Nodax was a Procter Gamble product. The originality of the grades is the variation in the nature of the radical of the ester. This company also produces PHA products. Genetically modified plants are also studied for producing PHB. Potential plants are watercress, colza (Arabidopsis thaliana), com and tobacco but yields are very low, just a few percent of the total weight of the vegetable. 

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