Injection administration

Administration of insulin—sites to be used rotation of injection sites (see Home Care Checklist Rotating Insulin Injection Sites) angle of injection administration at die time of day prescribed by the health care provider disposal of die needle and syringe... 

A second approach involves direct injection/administration of the nucleic-acid-containing vector to the target cell, in situ in the body. Examples of this approach have included the direct injection of vectors into a tumour mass, as well as aerosol administration of vectors (e.g. containing the cystic fibrosis gene) to respiratory tract epithelial cells. 

Absorption/Distributton - Gl and sublingual absorption of ergotamine is incomplete and erratic following oral administration, peak blood levels are reached in about 2 hours. Following intranasal administration, however, the mean bioavailability of dihydroergotamine mesylate is 32% relative to the injectable administration. 

Ganirelix and cetrorelix are absorbed rapidly after subcutaneous injection. Administration of 0.25 mg daily maintains GnRH antagonism. Alternatively, a single 3.0-mg dose of cetrorelix suppresses LH secretion for 96 hours. Abarelix is absorbed slowly after intramuscular injection and reaches a peak concentration 3 days after injection. It has a half-life of 13 days. After three initial doses on days 1, 13, and 28, abarelix is administered every 4 weeks. 

Immunotherapy Radiolabelled allergen Parietaria judaica Non injective administration Local immunotherapy... 

Penicillins can canse local effects such as pain, induration, and tenderness at the site of an intramuscular injection. Administration of penicillin intravenously can also canse bnrning or phlebitis. Hematologic toxicity prodnced by penicillins is rare, but various types of dysctasias such as leukopenia, granulocytopenia, abnormal platelet aggregation, and anemia have been reported. 

Arsenic Trioxide. Arsenic irioxide. Trisenux. arsenoa.-acid anhydride, As O. is supplied in solutions containing I mg/ntL for injection. It is stored at 2.5°C and reconslituinl by dilution with 100 to 250 mL of 5% Dextrose for Injccliin or 0.9% Stxlium Chloride for Injection. Administration i-by intravenous injection over 2 hours. The usual doseisO.IS mg/kg per day until bone marrow remission occurs, with tlx total number of doses limited to 60. 

Parenteral (injected) administration of drugs provides a solution to many problems associated with the oral delivery route. A drug injected into the blood circulation is considered to be completely bioavail-able thaefore, the quantity of the surfactants and otha inactive excipients in intravenous dosage forms are usually strictly limited. The most common alternative routes of parenteral drug administration are intramuscular or subcutaneous injections [2], Several otha injection routes are available to elicit rapid local reaction, such as intrathecal, intraarticular, and intracardiac. 

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