Inflammatory lung disease

Pease JE, Sabroe I. The role of interleukin-8 and its receptors in inflammatory lung disease implications for therapy. Am J Respir Med 2002 1(1) 19-25. 

Lung tissue injury is also mediated by reactive oxygen and nitrogen species in another inflammatory lung disease, acute respiratory distress syndrome (ARDS) [267], Lamb et al. 

New Anti-Microbial Treatment of Purulent-Inflammatory Lung Diseases in Patients Supported by Long-Term Artificial Ventilation of Lungs... 

The aim of this work was to investigate the potential use of FarGALS for prophylaxis and treatment of pyrogenic inflammatory lung disease in patients supported by long-term AVL. 

A 27-year-old man twice developed inflammatory lung disease (with a predominance of eosinophils) after inhaling crack cocaine (104). Glucocorticoid treatment led to prompt resolution on both occasions. 

Mustard gas exposure also causes inflammatory lung diseases, including acute respiratory distress syndrome (ARDS) (Calvet et al., 1994 Sohrabpour, 1984). A defective secretion of surfactant by alveolar type 11 cells has been implicated as one of the causative factors for the development of ARDS (Ansceschi, 1989). A major component of lung surfactant is DPPC (Stith and Das, 1982). The precursor of DPPC is normally l-pahnitoyl-2-oleolyl PC. DPPC is produced by deacylation and subsequent reacylation with palmitic acid at 2-position of glycerol moiety of the unsaturated phospholipid. 

Rahman, I. and MacNee, W. (1998). Role of transcription factors in inflammatory lung diseases. Thorax 53, 601-12. 

Azuma, A. (2001). Novel activity of erythromycin derivatives on inflammatory lung diseases. Recent Res. Devel. Respir. Crit. Care Med. (in press). 

Spina D. Phosphodiesterase-4 inhibitors in the treatment of inflammatory lung disease. Drugs 2003 63 2575-2594. 

Cronin E (1978) Kutane Reaktionen auf Kontaktallergene. Z Hautkr 53 362 Dash LA, Comstock GW, Flynn J-PG (1980) Isoniazid preventive therapy. Retrospect and prospect. Am Rev. Respir Dis 121 1039 Dasta J, Prior J, Kurzrok St (1979) Isoniazid-induced fever. Chest 75 196 David RB, Andersen HA, Stickler GB (1968) Nitrofurantoin sensitivity - report of a child with cronic inflammatory lung disease. Am J Dis Child 116 418 Davis RS, Stoler BS (1977) Febrile reactions to INH. N Engl J Med 297 337 Delaney RA, Miller DA, Gerbino PP (1977) Adverse effects resulting from nitrofurantoin administration. Am J Pharmacol 149, 26 (1977)... 

In most patients with hemoptysis the underlying cause is chronic or acute inflammatory lung disease, including pulmonary tuberculosis, bronchiectasis, cystic fibrosis and aspergilloma. All possible causes of hemoptysis are listed in Table 16.1. 

The two most prevalent chronic inflammatory lung diseases are asthma and chronic obstructive pulmonary disease (COPD). These diseases are a major and increasing global health problem. Both asthma and COPD share some clinical features, such as increased airway obstruction, mucous hypersecretion, acute exacerbations and respiratory symptoms. Asthma and COPD are identified by the presence of chronic inflammation of the airways, which is controlled by the increased expression of inflammatory proteins, including cytokines, chemokines, receptors, enzymes and... 

Enhanced exhalation of H2O2 and thiobarbituric acid reactive substances has been reported in various inflammatory lung diseases (Dohlman et al. 1993, Antczak et al. 1997, Nowak et al. 1999). In healthy volunteers the H2O2 exhalation revealed diurnal variation with two-peak values 0.45 0.29 pM and 0.43 0.22 iM at 12 00 and 24 00 h (Nowak et al. 2001). The lowest concentrations, 0.26 0.13 p.M and 0.25 0.26 p.M, were found at 20 00 and 8 00 h. Type II pneumocytes, alveolar macrophages, and endothelial cells produce HjOj (Kinnula et al. 1991). 

A number of inflammatory lung diseases are diffuse and, because of the low density of the lungs, the emission images appear to the naked eye to show no increase in FDG uptake relative to that observed in healthy subjects... 

Cordier JF, Peyrol S, Loire R. Bronchiolitis obliterans organizing pneumonia as a model of inflammatory lung disease. In Epler GR, eds. Diseases of the Bronchioles. New York Raven Press, Ltd., 1994 313-345. 

Iyer, S. S., Co, C., and Rojas, M. 2009. Mesenchymal stem cells and inflammatory lung diseases. Panminerva Med, 51,5-16. 

---