Bronchiolitis obliterans organizing pneumonia

Lung Bronchiolitis obliterans diagnosed with lung biopsy Bronchiolitis obliterans diagnosed with pulmonary function tests and radiology0 Bronchiolitis obliterans organizing pneumonia... 

A limited form of Wegener s granulomatosis with a bronchiolitis obliterans organizing pneumonia-hke variant has been reported in a 19-year-old man, a non-smoker, with ulcerative colitis, 6 months after the introduction of mesalazine 2.25 g tds orally (43). He recovered after mesalazine withdrawal and treatment with glucocorticoids. 

Interferon alfa was also suspected to be involved in one case of biopsy-proven bronchiolitis obliterans-organizing pneumonia (41). Clinical symptoms of pneumonitis appeared 3-12 weeks after the onset of interferon alfa therapy, and after withdrawal of treatment they usually completely resolved, either spontaneously or after a short course of glucocorticoid treatment. Immune-mediated pulmonary toxicity involving the activation of T cells was considered as a likely mechanism. The uncommon features of bronchiolitis obliterans-organizing pneumonia have been reported in three other patients who received interferon alfa together with ribavirin or cytosine arabino-side (42,43). 

Ogata K, Koga T, Yagawa K. Interferon-related bronchiolitis obliterans organizing pneumonia. Chest 1994 106(2) 612-13. 

Patel M, Ezzat W, Pauw KL, Lowsky R. Bronchiolitis obliterans organizing pneumonia in a patient with chronic myelogenous leukemia developing after initiation of interferon and cytosine arabinoside. Eur J Haematol 2001 67 (5-6) 318-21. 

Bronchiolitis obliterans organizing pneumonia has been attributed to ticlopidine (1). 

Alonso-Martinez JL, Elejalde-Guerra JI, Larrinaga-Linero D. Bronchiolitis obliterans-organizing pneumonia caused by ticlopidine. Ann Intern Med 1998 129(l) 71-2. 

COP was formerly referred to as bronchiolitis obliterans organizing pneumonia (BOOP) and is characterized by the histologic pattern of organizing pneumonia (OP). There is no gender predilection. Patients usually present between 50 and 60 years of age, and typically report... 

Akira M, Yamamoto S et al. (1998) Bronchiolitis obliterans organizing pneumonia manifesting as multiple large nodules or masses. AJR Am J Roentgenol 170 291 -295... 

Fenton ME, Kanthan R, Cockcroft DW. Nitrofurantoin-associated bronchiolitis obliterans organizing pneumonia report of a case. Can Respir J 2008 15(6) 311-2. 

Crestani B, Valeyre D, Roden S, et al. Bronchiolitis obliterans organizing pneumonia syndrome primed by radiation therapy to the breast. The Groupe d Etudes et de Recherche sur les Maladies Orphelines Pulmonaires (GERM 0 P). Am J Respir Crit Care Med 1998 158(6) 1929-1935. 

Bouchardy LM, Kuhhnan JE, Ball WC Jr., et al. CT findings in bronchiolitis obliterans organizing pneumonia (BOOP) with radiographic, clinical, and histologic correlation. J Comput Assist Tomogr 1993 17(3) 352 357. 

Katzenstein ALA. Acute lung injury patterns diffuse alveolar damage and bronchiolitis obliterans-organizing pneumonia. In Katzenstein and Askin s Surgical Pathology of Non-Neoplastic Lung Disease. 4th ed. Philadelphia WB Saunders,... 

Yousem SA, Lohr RH, Colby TV. Idiopathic bronchiolitis obliterans organizing pneumonia/cryptogenic organizing pneumonia with unfavorable outcome pathologic predictors. Mod Pathol 1997 10 864-871. 

Kitaichi M. Differential diagnosis of bronchiolitis obliterans organizing pneumonia. 

Chang J, Han J, Kim DW, et al. Bronchiolitis obliterans organizing pneumonia clinicopathologic review of a series of 45 Korean patients including rapidly progressive form. J Korean Med Sci 2002 17 179-186. 

A number of bronchiolar alterations have been described including proliferative bronchiolitis obhterans in FLD (82), peribronchiolar inflammation/ fibrosis with smooth muscle hypertrophy, and extrinsic narrowing of the small airways in pigeon breeder s disease (83), and less frequently, bronchiolitis obliterans organizing pneumonia (BOOP)-like lesions (84). 

Usui Y, Kimula Y, Miura H, et al. A case of bronchiolitis obliterans organizing pneumonia associated with primary Sjogren s syndrome who died of superimposed diffuse alveolar damage. Respiration 1992 59 122-124. 

Gammon RB, Bridges TA, al-Nezir H, et al. Bronchiolitis obliterans organizing pneumonia associated with systemic lupus erythematosus. Chest 1992 102 1171-1174. 

MuUer NL, Guerry-Force ML, Staples CA, et al. Differential diagnosis of bronchiolitis obliterans with organizing pneumonia and usual interstitial pneumonia clinical, functional, and radiologic findings. Radiology 1987 162 151-156. Cordier JF, Loire R, Brune J. Idiopathic bronchiolitis obliterans organizing pneumonia. Definition of characteristic clinical profiles in a series of 16 patients. Chest 1989 96 999-1004. 

Epler GR. Bronchiolitis obliterans organizing pneumonia definition and clinical features. Chest 1992 102 2S-6S. 

Nishimura K, Itoh H. High-resolution computed tomographic features of bronchiolitis obliterans organizing pneumonia. Chest 1992 102 268-318. 

Cordier JF. Cryptogenic organizing pneumonitis. Bronchiolitis obliterans organizing pneumonia. Clin Chest Med 1993 14 677-692. 

Wright L, King TE. Cryptogenic organizing pneumonia (idiopathic bronchiolitis obliterans organizing pneumonia) an update. Clin Pulm Med 1997 4 152-158. Nagai S, Izumi T. Bronchiolitis obliterans with organizing pneumonia. Cuir Opin Pulm Med 1996 2 419 23. 

Cordier JF, Peyrol S, Loire R. Bronchiolitis obliterans organizing pneumonia as a model of inflammatory lung disease. In Epler GR, eds. Diseases of the Bronchioles. New York Raven Press, Ltd., 1994 313-345. 

Peyrol S, Cordier JF, Grimaud JA. Intra-alveolar fibrosis of idiopathic bronchiolitis obliterans-organizing pneumonia. Cell-matrix patterns. Am J Pathol 1990 137 155-170. 

Lappi-Blanco E, Kaarteenaho-Wiik R, Soini Y, et al. Intraluminal fibromyxoid lesions in bronchiolitis obliterans organizing pneumonia are highly capillarized. Hum Pathol 1999 30 1192-1196. 

Majeski El, Harley RA, Bellutn SC, et al. Differential role for T cells in the development of fibrotic lesions associated with reovirus 1/L-induced bronchiolitis obliterans organizing pneumonia versus Acute Respiratory Distress Syndrome. Am J Respir Cell Mol Biol 2003 28 208-217. 

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