Immunological activity

Fig. 2. Structures of traditional antirlieumatic drugs having immunologic activity. See Table 2.

Table 2. Traditional Antirheumatic Drugs Having Immunological Activity ...

These studies showed that immunologically activated HHMC release PGD2 and LTC4. Interestingly, intravenous and intracoronary injection of traces of LTC4 and LTD4 may have several cardiovascular and metabolic effects [32]. 

Immunologically active polysaccharides from cell suspension of Helianthus annuus 1805... 

Kerjaschki D, Regele HM, Moosberger I, et al. Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates. J Am Soc Nephrol 2004 15 603-612. 

Some tumours secrete significant quantities of cytokines and additional regulatory molecules that can suppress local immunological activity. TGF-P (produced by many tumour types), for example, is capable of inhibiting lymphocyte and macrophage activity. 

No data were found on the effects of silver compounds on avian or mammalian wildlife. All controlled studies with silver were with domestic poultry, livestock, or small laboratory mammals. Signs of chronic silver ion intoxication in tested birds and mammals included cardiac enlargement, vascular hypertension, hepatic necrosis, anemia, lowered immunological activity, altered membrane permeability, kidney pathology, enzyme inhibition, growth retardation, and a shortened life span (Smith and Carson 1977 Freeman 1979 Fowler and Nordberg 1986 USPHS 1990). 

Equivalent to 500 or 5000 pg Ag/kg BW daily for 11 months Lowered immunological activity pathology of vascular, nerve, brain, and spinal cord tissues 3... 

Table 9.2 catalogs the recombinant proteins that are immunologically active and have been or are being studied in Phase I/II clinical trials in the United States. Several... 

Maluish, A.E. et al., The determination of an immunologically active dose of interferon-gamma in patients with melanoma, J Clin Oncol., 6, 434, 1988. 

Figure 9. Immunological activity of the oriented IgG films detected by fluorescence measurements.

The relatively slow phosphorylation of the 78 kDa band in response to either peptide stimulation or to the addition of DSCG suggests that this particular protein band may be involved in the termination of non-immunologically activated secretion [211-214],... 

Although small molecules do not usually stimulate antibody formation, antibodies against them can usually be raised if the small molecule, or hapten, is covalently attached to a large immunologically active carrier protein. 

DR on T cells, B cells and synovial lining cells, indicating strong immunological activity. RA is thought to be an autoimmune reaction, caused by an interaction between constitutional and environmental factors [14]. 

IL-12-stimulated IFN-y production and NK cell activation further potentates the overall immune response, not only to infectious agents but also against transformed cells. Cytotoxic T cells and NK cells represent two of the most important immune effector functions against cancer. IL-12-mediated immunological activity also renders this cytokine a potentially... 

Ledesma, A., Moral, V., Villalba, M., Salinas, J., and Rodriguez, R. (2(X)6). Ca + binding allergens from olive pollen exhibit biochemical and immunological activity when expressed in stable transgenic Arabidopsis. FEBS 273(19) 425-434. 

---