Human papilloma virus cervical cancer, cause

Cervical Cancer. In female AIDS patients, cancer of the cervix is observed with high frequency. Cervical cancer is a fairly common cancer in women, although it typically affects women of middle age or older. Infection with certain strains of human papilloma virus (HPV) that cause warts in the genital tract is an underlying cause of cervical cancer. 

The other viruses that are strongly implicated in human cancers include hepatitis C virus with liver cancer certain of the human papilloma viruses that cause warts on epithelial surfaces and cervical, penile and anal carcinomas human T-cell lymphotrophic virus type 1 with adult T-cell leukaemia/lymphoma syndrome and HIV with Kaposi s sarcoma. 

Epidemiological evidence points to a connection between long-term inflammation and the development of cancer that is characterized by dysplasia, hyperplasia, and sometimes irreversible cancer transformations. Nearly 15% of worldwide cancer incidence in humans is associated with microbial infection (Kuper et al. 2002). Chronic infections, with human papilloma virus or with hepatitis B or C viruses in immunocompetent human hosts, can lead to cervical and hepatocellular carcinomas, respectively. Infection with the human herpes virus can produce Kaposi s sarcoma in the skin. Karposi s cancers are seen more often in the IDS-compromised AIDS patients. After protracted inflammation, Helicobacter pylori can cause stomach irrita-... 

Viruses have been implicated in the development of at least two cancers. Infection with the human papilloma virus is a major risk factor for cervical cancer, and like any sexually transmitted disease, the cancer is more common amongst those who have had numerous partners and is almost unknown in nuns. But the most well-established link is between Burkitt s lymphoma and the Epstein-Barr virus (one of the herpes viruses) in African countries. In developed countries, this virus causes glandular fever (infectious mononucleosis), and the different progress of the disease in Africans is apparently due to an immune system that is usually suppressed through a long-term assault by malaria parasites like Plasmodium falciparum. 

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