Lymphotrophic viruses

The human immunodeficiency virus (HIV lymphadenopathy-associated virus, LAV human T-cell lymphotrophic virus type 3, HTLV III) is responsible for acquired immune deficiency syndrome (AIDS see Chapter 3). Because of the hazard and difficulties of growing the virus outside humans, a different approach has to be examined for determining viral sensitivity to disinfectants. 

Mitsuya H, Broder S. Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type... 

HTLV human T-cell lymphotrophic virus type... 

Edlich RF, Hill LG, Williams FM (2003) Global epidemic of human T-cell lymphotrophic virus type-I (HTLV-I) An update. J Long Term Eff Med Implants 13 127—140. 

Hara H, Morita M, IwaM T, Hatae T, Itoyama Y, Kitamoto T, Akizuki S, Goto I, Watanabe T (1994) Detection of human T lymphotrophic virus type I (HTLV-I) proviral DNA and analysis of T cell receptor... 

The other viruses that are strongly implicated in human cancers include hepatitis C virus with liver cancer certain of the human papilloma viruses that cause warts on epithelial surfaces and cervical, penile and anal carcinomas human T-cell lymphotrophic virus type 1 with adult T-cell leukaemia/lymphoma syndrome and HIV with Kaposi s sarcoma. 

Since 1980 three types of infectious human T-cell lymphotrophic viruses (HTLVs) have been identified. HTLV-I is frequently associated with adult forms of T-cell leukemia-lymphoma, HTLV-II with hairy T-cell leukemia, and HTLV-III (now called human immunodeficiency virus HIV) with acquired immunodeficiency syndrome (AIDS). Other related retroviruses have been isolated from human and primate populations. Molecular biologists have developed a wealth of information about the biology and genetics of retroviruses, including the complete sequencing of their genomes. Despite this enormous research effort it still... 

Among the known human retroviruses are human T-cell lymphotrophic virus (FITLY), which causes a form of leukemia, and human immunodeficiency virus (HIV), which causes acquired immune deficiency syndrome (AIDS). Both of these viruses can infect only specific cell types, primarily certain cells of the immune system and, in the case of HIV, some central nervous system neurons and glial cells. Only these cells have cell-surface receptors that interact with viral envelope proteins, accounting for the host-cell specificity of these viruses. Unlike most other retroviruses, HIV eventually kills its host cells. The eventual death of large numbers of... 

HTLC HTLV III HTN HTP HTR HTVD HUIFM HUR HUS HV H V HW hwb Hx Hz HZ HZO human T-cell leukemia virus human T-cell lymphotrophic virus type III hypertension House-Tree-Person test acute hemolytic transfusion reaction hypertensive vascular disease human leukocyte interferon meloy hemolytic uremic syndrome hemolytic uremic syndrome hallux valgus has voided hemigastrectomy and vagotomy heparin well housewife hot water bottle history hospitalization Hertz herpes zoster herpes zoster ophthalmicus... 

Human T-cell lymphotrophic virus Immunoglobulin electrophoresis Insulin antibody Insulin assay... 

Zidovudine is a synthetic thymidine analog with potent activity against a broad spectrum of retroviruses including HIV-1, HlV-2, and human T-ceU lymphotrophic viruses (HTLV) 1 and II. The drug has no impact in cells already infected with HIV. It is most effective in activated lymphocytes because the phosphorylating enzyme, thymidine kinase, is S-phase specific. 

Mitsuya H, Broder S (1986) Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type Ill/lymphadenopathy-associated virus (HTLV-III/LAV) by 2, 3 -dideoxynucleosides. Proc Natl Acad Sci USA 83 1911-1915 Miyako K, Kai Y, Me T, Takeshige K, Kang D (1997) The content of intracellular mitochondrial DNA is decreased by l-methyl-4-phenylpyridium ion (MPP ). J Biol Chem 272 9605-9608... 

There are eight members of the herpesvirus family able to infect humans HHV-1 (herpes simplex virus 1, HSV-1) HHV-2 (herpes simplex virus 2, HSV-2) HHV-3 (varicella zoster virus,VZV) HHV-4 (Epstein-Barr virus, EBV) HHV-5 (cytomegalovirus, CMV) HHV-6 (human B-cell lymphotrophic virus or roseolovirus) HHV-7 (closely related to HHV-6) HHV-8 (a type of the rhadinovirus). 

Easley R, Carpio L, Guendel I, Klase Z, Choi S, Kahn-Hall K, Brady JN, Kashanchi F. Human T-lymphotrophic virus type 1 transcription and chromatin-remodeling complexes. J Virol. 2010 84 4755-68. 

Marms A, Blattner WA. The epidemiology of the human T-cell lymphotrophic virus type 1 and type II etiologic rule in human disease. Transfusion. 1991 31 67-75. 

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