High production volume challenge program

This is known as the Voluntary Childrens Chemical Evaluation Program (VCCEP). 

The study looked only for health screening data as established by the Organization for Economic Development s (OECD) Screening Information Data Set (SIDS), and not at the full SIDS set. 

Office of Pollution Prevention and Toxics, Chemical Hazard Data What Do We Really Know About the Safety of High Production Volume Chemicals 2 (Apr. 1998), available at http //www.epa.gov/hpv/pubs/general/hazchem.pdf 

HPV chemicals are those which are manufactured in or imported into the United States in amounts equal to or greater than 1 million pounds per year. The U.S. HPV chemicals were identified through information collected under the TSCA Inventory Update Rule (lUR). Organic chemicals that are manufactured in, or imported into, the United States in amounts equal to or exceeding 10,000 pounds per year are subject to reporting under the TSCA lUR. Reporting is required every 4 years. 

In 1998, US-EPA s Administrator invited the Chief Executive Officers of more than 900 chemical companies that account for most of the U.S. manufacture and import of HPV chemicals to participate in the HPV Challenge Program. The program encourages chemical manufacturers to voluntarily test chemicals for which little or no health or environmental effects data were publicly available. 

The output of the HPV program is fed into the OECD SIDS program (see Section 2.2.3). 

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EPA (2008b). TSCA inventory reset and inorganic high production volume challenge programs notice of pubhc meeting. Fed Reg 73, 70640—70643. 

See Chapter 10. Voluntary Initiatives for a discussion of the High Production Volume Challenge Program, and see Chapter 2. TSCA s Scope for a discussion of nanomaterials. 

Calculated from Sunset Dates of Chemicals Subject to Final TSCA Section 4 and Related 12(b) Actions, September 1,2009, available at http //www.epa.gov/oppt/chemtest/pubs/sunsettable. html. This total does not include studies performed pursuant to the voluntary initiatives such as the High Production Volume challenge, but does include HPV chemicals that were not voluntarily studied and were later the subject of test rules. See Chapter 10. Voluntary Initiatives, for a discussion of the HPV and other voluntary programs. 

HPVIS provides complete and easy access to technical health and environmental effect information on chemicals that are manufactured or imported to US in volumes greater than IMM lbs per year. Information in this database are submitted through HPV Challenge Program. HPVIS allows users to search for summary information, test plans, and new data on high production volume chemicals as they are developed. 

EPA, High Production Volume (HPV) Challenge Program (http //www.epa.gov/chemrtk/ volchall.htm). 

High Production Volume (HPV) Challenge is a program defined in 1998 by the EPA for toxicological assessment of substances that are manufactured or imported into the United States. 

Rosenkranz, H. S., and Cunningham, A. R. (2000). The high production volume chemical challenge program The relevance of the in vivo micronucleus assay. Regul Toxicol Pharmacol 31, 182-189. 

Process design product stewardship and Eastman s voluntary participation in the EPA High-Production Volume Chemical Challenge Program is discussed. There is also a global target to reduce the quantity of raw materials used from 1.28 pounds per pound in 1996 to 1.26 in 2000 (N.B. the figure for 1998 was 1.24 pounds per pound). 

It is not uncommon for activists to proceed on both fronts with respect to issues of interest. For example, challenges to the voluntary High Production Volume (HPV) Challenge Program were initiated under both 20 and 21. On December 27, 1999, People for the Ethical Treatment of Animals (PET A) on its own behalf and on behalf of four other organizations, including Physicians Committee for Responsible Medicine, filed a citizens petition... 

High Production Volume Chemical Challenge Program Test Plan for the Phthalate Esters Category. Prepared by ExxonMobil Biomedical Sciences Inc. for the Phthalate Esters Panel HPV Testing group of the American Chemistry Council, December 10, 2001... 

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