Biomedical sciences

Chair of Cell Biology, University of Nottingham Medical School, School of Biomedical Sciences, Nottingham, NG7 2UH... 

Margaret R Cunningham, Robin Plevin Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK... 

Many years ago chitin was seen as a scarcely appeahng natural polymer due to the variety of origins, isolation treatments and impurities, but the works of several analytical chemists and the endeavor of an increasing number of companies have qualified chitins and chitosans for sophisticated applications in the biosciences. Chemistry today offers a range of finely characterized modified chitosans for use in the biomedical sciences. Moreover, surprising roles of these polysaccharides and related enzymes are being unexpectedly discovered [351]. 

Biomimetic polymers in pharmaceutical and biomedical sciences. Eitropean Journal of Pharmaceutics and Biopharmaceutics, Vol. 58, 2, (September 2004), pp. (385-407), ISSN 0939-6411... 

This third part of the book will be devoted mainly to the problem of addressing complex pollution problems and how they can be studied employing new biomarker assays that exploit new technologies of biomedical science. Chapter 13 will give a broad overview of this question. The following three chapters, The Ecotoxicological Effects of Herbicides, Endocrine Disrupters, and Neurotoxicity and Behavioral Effects, will all provide examples of the study of complex pollution problems. 

Phosphazene polymers can act as biomaterials in several different ways [401, 402,407]. What is important in the consideration of skeletal properties is that the -P=N- backbone can be considered as an extremely stable substrate when fluorinated alcohols [399,457] or phenoxy [172] substituents are used in the substitution process of the chlorine atoms of (NPCl2)n> but it becomes highly hydrolytically unstable when simple amino acid [464] or imidazole [405-407] derivatives are attached to the phosphorus. In this case, an extraordinary demolition reaction of the polymer chain takes place under mild hydrolytic conditions transforming skeletal nitrogen and phosphorus into ammonium salts and phosphates, respectively [405-407,464]. This opens wide perspectives in biomedical sciences for the utilization of these materials, for instance, as drug delivery systems [213,401,405,406,464] and bioerodible substrates [403,404]. 

Joe C. Davis Professor of Biomedical Science, Director, Vanderbilt Diabetes Center, Professor of Molecular Physiology and Biophysics and of Medicine, Vanderbilt University, Nashville, Tennessee... 

Nicholson, J. W., Braybrook, J. H. Wasson, E. A. (1991). The biocompatibility of glass-poly(alkenoate) (glass-ionomer) a review. Journal of Biomedical Science, Polymer Edition, 2, 277-85. 

DOE. 1986. Pacific Northwest Laboratory Annual Report for 1985 to the DOE Office of Energy Research, Part 1-Biomedical sciences Fetal and juvenile radiotoxicity. Richland, WA US Department of Energy. Contract DE-AC06-76RLO 1830. 

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