High performance liquid chromatography with tandem mass spectrometry , determination

Sottani C, Zuchetti M, Zaffaroni M et al. (2004) Validated procedure for simultaneous trace level determination of the anti-cancer agent gemcitabine and its metabolite in human urine by high-performance liquid chromatography with tandem mass spectrometry. Rapid Communications in Mass Spectrometry 18 1017-1023... [Pg.613]

Jemal, M. and Xia, Y.-Q., The need for adequate chromatographic separation in the quantitative determination of drugs in biological samples by high performance liquid chromatography with tandem mass spectrometry, Rapid Commun. Mass Spectrom., 13, 97, 1999. [Pg.126]

Canezin J, Cailleux A, Turcant A, Le Bouil A, Harry P, Allain P (2001) Determination of LSD and its metabolites in human biological fluids by high-performance liquid chromatography with electrospray tandem mass spectrometry. J Chromatogr B Biomed Sci Appl 765 15-27... [Pg.207]

Raices R.S.L. et al., 2003. Determination of stavudine in human serum by online solid-phase extraction coupled to high-performance liquid chromatography with electrospray ionization tandem mass spectrometry Application to a bioequivalence study. Rapid Commun Mass Spectrom 17 1611. [Pg.296]

Hamscher G., S. Sczesny, H. Hdper, and H. Nau (2002). Determination of persistent tetracycline residues in soil fertilized with liquid manure by high-performance liquid chromatography with electron spray ionization tandem mass spectrometry. Analytical Cheminstry 74 1509-1518. [Pg.264]

Tricyclazole and tetracycline have been determined by gas chromatography - mass spectrometry [247]. Persistent tetracycline residues have been determined in soil by high-performance liquid chromatography with electrospray ionisation tandem mass spectrometry [248]. [Pg.111]

Constanzer, M.L. Chavez, C.M. Matuszewski, B.K. Picogram determination of finasteride in human plasma and semen by high-performance liquid chromatography with atmospheric-pressure chemical-ionization tandem mass spectrometry. J.Chromatogr.B, 1994, 658, 281-287... [Pg.612]

Zell M., Husser C., and Hopfgartner G., 1997b. Column-switching high-performance liquid chromatography combined with ionspray tandem mass spectrometry for the simultaneous determination of the platelet inhibitor Ro 44-3888 and its pro-drug and precursor metabolite in plasma. J Mass Spectrom 32 23. [Pg.297]

Karlsson AA, Michelsen P, Odham G. 1998. Molecular species of sphingomyelin determination by high-performance liquid chromatography/mass spectrometry with electrospray and high-performance liquid chromatography/tandem mass spectrometry with atmospheric pressure chemical ionization. J Mass Spectrom 33 1192. [Pg.171]

Schneider H, Ma L, Glatt H. 2003. Extractionless method for the determination of urinary caffeine metabolites using high-performance liquid chromatography coupled with tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 789 227. [Pg.175]

Zell, M. Husser, C. Hopfgartner, G. Low picogram determination of Ro 48-6791 and its major metabolite, Ro 48-6792, in plasma with columnswitching microbore high-performance liquid chromatography coupled to ion spray tandem mass spectrometry. Rapid Commun. Mass Spectrom. 1997, 11, 1107-1114. [Pg.59]

Awidi A et al (2010) Determination of imatinib plasma levels in patients with chronic myeloid leukemia by high performance liquid chromatography-ultraviolet detection and liquid chromatography-tandem mass spectrometry methods comparison. Leuk Res 34 714-717... [Pg.243]

Abbara C, Bardot I, Cailleux A, Lallement G, Le Bouil A, Turcant A, Clair P, Diquet B (2008) High-performance liquid chromatography coupled with electrospray tandem mass spectrometry (LC/MS/MS) method for the simultaneous determination of diazepam, atropine and pralidoxime in human plasma. J Chromatogr B 874 42-50... [Pg.343]

Micro-solid phase extraction coupled with high-performance liquid chromatography-tandem mass spectrometry for the determination of stimulants, hallucinogens, ketamine and phencyclidine in oral fluids. Anal Chim Acta 675(2) 132-137. doi 10.1016/j.aca.2010.07.011... [Pg.393]

H. Rosing, M. J. X. HUlebrand, J. M. Jimeno, A. Gomez, and P. Floriano, Quantitative determination of Eteinascidin 743 in human plasma by miniaturized high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry,/. Mass Spectrom. 33 (1998), 1134-1140. [Pg.344]

High-performance liquid chromatography-tandem mass spectrometry method for the determination of gemifloxacin in human plasma was based on the protein precipitation of plasma samples with acetonitrile containing [ C Ha] gemifloxacin as an internal standard. The supernatant was injected onto a PLRP-S column without any further clean-up. The mass spectrometer was operated in positive ion mode, and the ions were detected in multiple reaction-monitoring (MRM) mode. The assay requires 50 gl of plasma and is precise and accurate within the range 10-5000 ng/ml [15]. [Pg.163]