Heat shock factors

Clos, J., Westwood, J.T., Becker, P.B., Wilson, S., Lambert, K., Wu, C. (1990). Molecular cloning and expression of a hexameric Drosophila heat shock factor subject to negative regulation. Cell 63, 1085-1097. 

Clos, J., Rabindran, S., Wisniewski, J., Wu, C. (1993). Induction temperature of human heat shock factor is reprogrammed in Drosophila cell environment. Nature 363,252-254. 

Hensold, J.O., Hunt, C.R., Calderwood, S.K., Housman, D.E., Kingston, R.E. (1990). DNA binding of heat shock factor to the heat shock element is insufficient for transcriptional activation in murine erythroleukemia cells. Mol. Cell Biol. 10, 1600-1608. 

Jakobsen, B.K. Pelham, H.R.B. (1988). Constitutive binding of yeast heat shock factor to DNA in vivo. Mol. Cell. Biol. 8, 5040-5042. 

Jurivich, D.A., Pachetti, C., Qui, L., Welk, J.F. (1995). Salicylate triggers heat shock factor differently than heat. J. Biol. Chem. 270, 24489-24495. 

Lee, B.S., Chen, J., Angelidis, C., Jurivich, D.A., Morimoto, R.l. (1995). Pharmacological modulation of heat shock factor 1 by antiinflammatory drug results in protection against stress-induced cellular damage. Proc. Natl. Acad. Sci. USA 92, 7207-7211. 

Nakai, A., Morimoto, R.I. (1993). Characterization of a novel chicken heat shock transcription factor, heat shock factor 3, suggests a new regulatory pathway. Molecular Cellular Biology 13, 1983-1997. 

Sarge, K.D., Zimarino, V., Holm, K., Wu, C Morimoto, R.l. (1991). Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA binding ability. Genes Dev. 5, 1902-1911. 

Sarge, K.D., Murphy, S.P., Morimoto, R.l. (1993). Activation of heat shock gene transcription by heat shock factor 1 involves oligomenzation, acquisition of DNA binding activity, and nuclear localization and can occur in the absence of stress. Mol. Cell. Biol. 13. 1392-1407. 

Sorger, P.K. Pelham, H.B.R. (1988). Yeast heat shock factor is an essential DNA binding protein that exhibits temperature-dependent phosphorylation. Cell 54, 855-864. 

Theodorakis, N.G., Zand, D.J., Kotzbauer, P.T., Williams, G.T., Morimoto, R.I. (1989). Hemin induced transcriptional activation of the hsp70 gene during erythroid maturation in K562 cells is due to a heat shock factor mediated stress response. Mol. Cell. Biol. 9,3166-3173. 

Zimarino, V., Tsai, C., Wu, C. (1990a). Complex modes of heat shock factor activation. Mol. Cell. Biol. 10, 752-759. 

HSF heat shock factor protein MERRF myoclonus epilepsy with ragged red fibers... 

TF transcription factor, R receptor, Fur ferric uptake regulation protein, NF-kB nuclear factor-kB, AP-1 activator protein-1, Egr-1 early growth response-1, VDR la,25-dihydroxy-vitamin D3 receptor, RXR retinoid X receptor, PPARy peroxisome proliferator-activated receptor y NFAT nuclear factor of activated T-cells, HSF heat shock factor, p53 tumor suppressor p53, HIF-1 hypoxia inducible factor-1. ... 

Perisic, O., Xiao, H. Lis, J.T. (1989). Stable binding of Drosophila heat shock factor to head-to-head and tail-to-tail repeats of a conserved 5 bp recognition unit. Cell 59, 797-806. 

Sorger P. K. (1991). Heat shock factor and the heat shock response. Cell 65 363-366. 

Heat shock factor (HSF) Heat shock GAANNTTC... 

Figure 2.2 Proposed mechanism of inducible gene expression mediated by heat shock and certain other pathophysiological conditions. Adapted from Zou et al. (1998). Terminology HSF1 (heat shock factor 1) HSP (heat shock proteins) HSE (heat shock element in DNA) P (phosphorylation).

Mivechi, N.F., Ouyang, H. and Hahn, G.M. (1992) Lower heat shock factor activation and binding and faster rate of HSP-70A messenger RNA in heat sensitive human leukemias. Cancer Res., 52, 6815-6822. 

Sarge, K.D., Park-Sarge, O.Y., Kirby, J.D., Mayo, K.E. and Morimoto, R.I. (1994) Regulated expression of heat shock factor 2 in mouse testis potential role as a regulator of HSP gene expression during spermatogenesis. Biol. Reproduct., 50, 1334-1343. 

Schuetz, T.J., Gallo, G.J., Sheldon, L., Tempst, P. and Kingston, R.E. (1991) Isolation of cDNA for HSF2 evidence of two heat shock factor genes in humans. Proc. Natl. Acad. Sci. USA, 88, 6910-6915. 

Sistonen, L., Sarge, K.D., Phillips, B., Abravaya, K. and Morimoto, R. (1992) Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells. Mol. Cell. Biol., 12, 4104 1111. 

Chi, N.C., and Karliner, J.S. 2004. Molecular determinants of responses to myocardial ischaemia-reperfusion injury focus on hypoxia-inducible and heat shock factors. Cardiovasc. Res. 61 437-447. 

Ali, A., S. Bharadwaj, R. O Carroll, and N. Ovsenek (1998). Hsp90 interacts with and regulates the activity of heat shock factor 1 in Xenopus oocytes. Mol. Cell. Biol. 18 4949-4960. 

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