Fully automated methods

The analyses of illicit drugs and metabolites in the sampled waters were performed following a previously described and validated fully automated method based on on-line solid phase extraction-liquid chromatography-tandem mass spectrometry (on-line SPE-LC-MS/MS) [19]. 

Christiaens B. et al., 2004. Fully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for online sample clean-up, J Chromatogr A 1056. 

Ernst published a method for the identification of cross-peaks in two-dimensional spectra based on the recognition of their unique anti-phase portion in phase-resolved two-dimensional spectra. Glaser and Kalbitzer presented a generalized and fully automated method for the recognition of cross-peaks in two-dimensional NMR spectra. 

Dl. Desnick, R. J., Tmex, J. H., et al., A fully automated method for identification of Tay-Sachs disease carriers by tear beta-hexosaminidase assay. Prog. Clin. Biol. Res. 18, 245—265 (1977). 

Acceptance Used as a routine, standard method Development of fully automated methods for high throughput analysis open access instruments standard methods outsourcing. 

Breaud AR, Harlan R, Di Bussolo JM et al (2010) A rapid and fully-automated method for the quantitation of tricyclic antidepressants in serum using turbulent-flow liquid chromatography-tandem mass spectrometry. Clin Chim Acta 411 825-832... 

Phenylurea herbicides are widely used for weed control around the world. This method works directly on a filtered river water sample. This fully automated method was accomplished on the PROSPEKT automated system and was interfaced directly to an HPLC. Figure 10.18 shows the configuration of the system. It consists of the solvent delivery unit (SDU), which prepares the sorbent, pumps the sample, and elutes the cartridge. The system also includes Marathon autosampler, which coordinates the 10-mL water samples, and the... 

Fully Automated Methods. The second approach to expert system V V has been the use of verification tools. These tools generally analyze the source code for the expert system. This analysis does not involve executing or exercising the system. Verification tools for expert systems are similar to those of conventional software. These tools process the source code and in some cases descriptions of the source code looking for problems that can be determined mechanistically by a program. Conventional tools can detect ... 

After ALADDIN, this author and Martin parted ways, but each played a role in the rise of two distinct pharmacophore discovery methods. In 1990, this author joined, as a founding member and first scientist, a new company in Silicon Valley, BioCAD, dedicated to the development of software to assist drug discovery. Our software, Catalyst, contained three components conformational analysis, 3D database searching, and Hypothesis Generation —a novel approach to pharmacophore discovery. Catalyst represented the first fully automated method for pharmacophore discovery. 

A fully automated method, based on online SPE-LC-MS/MS analysis, has been developed for the determination of some most relevant endocrine disrupting chemicals in water samples. 

T. Korenaga and H. Ikatsu, Flow Injection Analysis System with Personal Computer Application to a Fully Automated Method for the Measurement of Dissolved Chemical Oxygen Demand in River Waters [in Japanese]. Bunseki Kagaku, 31 (1982) 517. 

For the purpose of our investigation a test indicating ammonia and total oxidized forms of inorganic nitrogen is highly useful. To satisfy this need we developed a fully automated method comprised of two steps first, an eflBcient reduction of nitrite and nitrate by copper-zinc alloy to... 

Fully automated methods, such as pultrusion (hot curing cycle), filament winding (cold or hot cured), injection moulding, etc. 

The variability of the QT measurement (SD of AQTc) can be reduced to around 5-6 ms by the use of more computer-intensive techniques with optimization of the ECG extraction and measurement of substantially more beats per timepoint (Dalen et al. 2010 Darpo et al. 2011) see Fig. 3 for an example. There may be concerns regarding the ability of fully automated methods to identify individual patients with... 

Colombo, M. Sirtoii, F.R. Rizzo, V. A Fully Automated Method for Accurate Mass Determination Using High-Performance Liquid Chromatography With a Quadrapole/Orthogonal Acceleration Time-of-Flight Mass Spectrometer. Rapid Commun. Mass Spectrom. 2004, 7S, 511-517. 

Sequence design can be intuitive or partially or fully automatic. A few fully automated methods for sequence design have been proposed their conceptual foundations are discussed below. But even the fully automated methods have an important subjective aspect. There exist quite a number of potentially conflicting objectives in sequence design. Some of these are ... 

M. Riley, and A. Gochman, A fully automated method for the determination of serum protein bound... 

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