Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

High-throughput LC/UV/MS analysis

FIGURE I Schematic diagram of high-throughput LC/UV/MS analysis for equilibrium solubility assay. ... [Pg.416]

High-Throughput Parallel LC/UV/MS Analysis of Combinatorial Libraries... [Pg.3]

We have optimized an eight-way MUX coupled to a TOFMS analyzer to carry out eight-channel parallel LC/UV/MS analysis of combinatorial libraries14 in the past 2 years. This system has not only provided the capacity needed for library analysis, but also enabled simultaneous evaluation of experimental parameters to expedite the method development process. In this chapter, we discuss the optimization of this system and present a high-throughput protocol for combinatorial library analysis. We also compare the eight-channel parallel LC/UV/MS system to a conventional single channel LC/UV/MS system in terms of performance and operation. [Pg.5]

It is generally accepted that an analysis by LC/UV/MS coupled with a H NMR is sufficient to characteri.se a compound and provide an estimation of purity. The massive increase in sample numbers through combinatorial approaches has led to an urgent need for the above techniques to be available to the chemist on demand. This has cataly.sed the development of high-throughput walk-up open-access LC/UV/MS systems. [Pg.145]


See other pages where High-throughput LC/UV/MS analysis is mentioned: [Pg.3]    [Pg.4]    [Pg.5]    [Pg.7]    [Pg.9]    [Pg.11]    [Pg.13]    [Pg.15]    [Pg.17]    [Pg.19]    [Pg.20]    [Pg.3]    [Pg.4]    [Pg.5]    [Pg.7]    [Pg.9]    [Pg.11]    [Pg.13]    [Pg.15]    [Pg.17]    [Pg.19]    [Pg.20]    [Pg.145]    [Pg.495]    [Pg.419]    [Pg.356]    [Pg.143]    [Pg.144]    [Pg.204]    [Pg.206]    [Pg.216]    [Pg.406]    [Pg.130]    [Pg.267]    [Pg.512]    [Pg.334]    [Pg.196]    [Pg.198]    [Pg.267]    [Pg.133]    [Pg.479]    [Pg.256]    [Pg.290]    [Pg.316]    [Pg.543]    [Pg.549]    [Pg.559]    [Pg.593]    [Pg.594]    [Pg.3428]    [Pg.122]    [Pg.196]    [Pg.48]    [Pg.529]    [Pg.188]    [Pg.1908]    [Pg.188]   
See also in sourсe #XX -- [ Pg.416 ]




SEARCH



High-throughput

High-throughput analyses

LC-MS analysis

LC/MS

MS analysis

MS, high-throughput

UV analysis

© 2024 chempedia.info