Creatine monohydrate

B. Banerjee, U. Sharma, K. Balasubramanian, M. Kalaivani, V. Kalra and N. R. Jagannathan, Effect of creatine monohydrate in improving cellular energetics and muscle strength in ambulatory Duchenne muscular dystrophy patients a randomized, placebo-controlled 31P MRS study. Magn. Reson. Imaging, 2010,28,698-707. 

Those who have used creatine products such as creatine monohydrate or creatine phosphate realize the effects that more creatine can provide. When anabolic/androgenic steroids (AAS) are administered they cause an increase in Phosphocreatine (CP) synthesis. Let me explain why this creatine stuff is such a cool thing. 

There are other forms of Creatine. Creatine Citrate is very water soluble but requires twice the amount to equal the same amount of Creatine Monohydrate. Creatine Phosphate is another option but cost to effectiveness makes the product less effective than Creatine Monohydrate. 

How many times have you heard some gym supplement expert say that the weight gained from creatine is just water Well, researchers wrote an interesting paper concerning creatine called Dangott, B. Schulz, E. Mozdziak, P.E. "Dietary Creatine Monohydrate supplementation increases satellite cell mitotic activity during compensatory hypertrophy" in International Journal of Sports Medicine 21 13-16,2000. What the heck is that, huh ... 

OFFICIAL NAMES Creatine monohydrate, creatine phosphate... 

Creatine monohydrate, the most popular form of off-the-shelf creatine supplementation, is an odorless, white, water-soluble powder. Its chemical name is N-(ammoimmomethyl)-N-methylglycine monohydrate. 

In addition to unadulterated creatine monohydrate, special formulations of the supplement are available in the U.S. market which may include supplemental phosphates, amino acids, carbohydrates, and other dietary additives. There have also been laboratory reports of creatine that has been altered during the manufacturing process with other unlabeled and potentially harmful substances. 

Creatine is sold in powdered, liquid, tablet, capsule, and chewing-gum formulations. The most popular formulation of creatine is creatine monohydrate, which is also the creatine formula that has been most extensively tested in clinical studies. Pure creatine monohydrate is a white, odorless, crystal powder with a faintly sweet taste. Other variations of creatine supplements are available, including creatine citrate and creatine phosphate. However, the clinical data on the effectiveness of these formulas is limited. 

Creatine may also be a promising treatment for other types of physical rehabilitation. Research conducted at Catholic University Leuven (Belgium) looked at the role of creatine in the recovery of university students who had been immobilized in full leg casts for two weeks. The students who received creatine monohydrate supplements had greater muscle function and mass than the students who received a placebo at both three weeks and 10 weeks of physical rehabilitation. 

Several U.S. researchers speculate that the authors of the French report mistakenly drew their conclusion from published studies analyzing naturally occurring creatine found in protein-rich animal products such as beef and pork. When these creatine-containing foods are heated and cooked, the creatine and amino acids interact to form compounds known as heterocyclic amines (HCAs), which have been shown to cause cancer in animal studies. The level of HCAs can vary with cooking method and other factors. Creatine monohydrate does not contain HCAs, and as of early 2002, no published or reported clinical research existed to demonstrate that creatine monohydrate taken in supplement form causes cancer. 

Some of the SN/AEMS incidents involved creatine monohydrate that was mixed with or taken with other supplements and substances, so it is difficult to determine to what extent creatine played a role in these reactions. There have also been anecdotal case reports of hypertension (high blood pressure) and elevated liver enzymes in athletes taking creatine supplements. 

According to the Physician s Desk Reference (PDR) for Nutritional Supplements, there are no known adverse interactions between creatine monohydrate supplements and prescription drugs, herbs, and/or other dietary supplements. However, the effects of creatine may be decreased or altered by the use of other drugs or supplements, so anyone considering taking the supplement should consult a physician first. 

Anyone deciding to take creatine monohydrate should obtain the supplement from a reputable manufacturer that observes stringent quality control procedures and industry-accepted good manufacturing practices... 

Crazy edge see PCP (phencyclidine) Creatine monohydrate see Creatine Creatine phosphate see Creatine Creeper see Heroin Creo-Terpin see Dextromethorphan... 

Tarnopolsky M, Martin J. Creatine monohydrate increases strength in patients with neuromuscular disease. Neurology 1999 52(4) 854-857. 

Persky AM and Brazeau GA (2001) Clinical pharmacology of the dietary supplement creatine monohydrate. Pharmacology Reviews Reviews S3,161-76. 

H. Mendel and D. G. Hodgkin. Acta Cryst. 7, 443-6 (1954). x-ray crystal structure of creatine monohydrate. 

Vahedi K, Domigo V, Amarenco P, Bousser MG. Ischaemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for body building. J Neurol Neurosurg Psychiatry 2000 68(1) 112—113. 

Chang CT, Wu CH, Yang CW, et al. Creatine monohydrate treatment alleviates muscle cramps associated with haemodialysis. Nephrol Dial Transplant 2002 17 1978-1981. 

Creatine Monohydrate is obtained from food (especially red meat -- 2 lbs. of steak has about 4 grams of creatine) and is also formed in the liver from the amino acids arginine, glycine and methionine. Creatine is then taken up by skeletal muscle where it forms phosphocreatine, the high energy phosphate compound. 

Q There are so many people telling me different ways to take creatine monohydrate that I had to get some expert advice. I want to gain some muscle but not put on a lot of fat. Does it really matter how I take the stuff Help ... 

Optional Day 74-83 Humulin-R lOiu 2xd with creatine monohydrate lOg BCAA lOg Maximum Neural Stimulation Phase... 

Creatine Creatine monohydrate creatine monophosphate Athletic performance enhancement Gastrointestinal irritation. 

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