Compensatory hypertrophy

Asmathbanu I, Kaliwal BB. 1997. Temporal effect of methyl parathion on ovarian compensatory hypertrophy, follicular dynamics and estrous cycle in hemicastrated albino rats. J Basic Clin Physiol Pharmacol 8 237-254. 

Dhondup P, Kaliwal BB. 1997. Inhibition of ovarian compensatory hypertrophy by the administration of methyl parathion in hemicastrated albino rats. Reprod Toxicol 11 77-84. 

Kaliwal, B. B., and M. A. Rao. Effect of carrot seed (Daucus carota) extract on estrous cycle as compared with that of estradiol-17-beta in albino rats. Comp Physiol Ecol 1983 8(2) 101-104. Kaliwal, B. B., and M. A. Rao. Inhibition of ovarian compensatory hypertrophy by carrot seed (Daucus carota) extract of estradiol-17beta in hemi-castrated albino rats. Indian J Exp Biol 1981 19 1058-1060. 

How many times have you heard some gym supplement expert say that the weight gained from creatine is just water Well, researchers wrote an interesting paper concerning creatine called Dangott, B. Schulz, E. Mozdziak, P.E. "Dietary Creatine Monohydrate supplementation increases satellite cell mitotic activity during compensatory hypertrophy" in International Journal of Sports Medicine 21 13-16,2000. What the heck is that, huh ... 

Long-term follow up over 12 months of additional 40 patients (total of 60) was recently completed for TOPCARE-AMI (30), and confirmed initial good safety profile and sustained improvement in EF and LV contractility by MRI. The total LV mass decreased the overall suggesting that deleterious compensatory hypertrophy and remodeling of adjacent myocardium did not occur. Restenosis rate remained at 21 % and no lethal arrhythmia was reported. 

Lobar agenesis In most cases, agenesis affects the right lobe. This very rare abnormality is mostly associated with other congenital malformations, especially of the biliary system. The unaffected liver lobe will generally develop compensatory hypertrophy. (22, 40, 49)... 

Measurement of separate kidney function is particularly indicated for the management of unilateral and bilateral uropathy, staging of disease, assessment of unilateral compensatory hypertrophy, and in cases where x-ray examinations (intravenous pyelography, etc.) are contraindicated (Hilson et al. 1976 Nielsen et al. 1977 Russel 1985 Wassner 1981). 

Mahadevaswami, M. P., Jadaramkunii, U. C,. Hiremath. M. B., and Kaliwal, B. B. (2000), Effect of inanen/eh on ovarian compensatory hypertrophy and biochemical constituents in hemicastrated albino rat. Repmd. Toxicol. 14, 127-134. 

K43 Kolia, V. E., Bilich, G. L., Porollo, V. I., Otmakhov, V. N. and Suslova, O. I. Effect of potassium orotate on compensatory hypertrophy of the remaining lung after left-sided pulmonectomy. Eksp. Khir. Anesteziol., 4, 35-38 (1975) (Russ.)... 

Some of the metabolic changes in the kidney in such experiments are known. Sodium is temporarily depleted, and then ammonium excretion is markedly increased. The increased excretion of ammonium ions is accompanied by de novo synthesis of glutaminase. Although the adaptation just described can be expected, other metabolic changes observed in the kidney of animals made acidotic experimentally are somewhat more difficult to understand. They include increased activity of the enzymes of the hexose monophosphate shunt, increased rates of gluconeogenesis and lipogenesis, and compensatory hypertrophy of the kidney, somewhat reminiscent of that observed after unilateral nephrectomy [48]. 

It thus appears that the tissues of an organ such as the kidney secrete into the body substances which inhibit kidney tissue development, and that compensatory hypertrophy after kidney removal may be ascribed to a shortage of these inhibitors. On this view the relative size of each organ must be dictated by the concentration within the body space of... 

Compensatory hypertrophy following unilateral nephrectomy is usually complete within 2 years. Compensatory hypertrophy is more rapid in infants than in children or adults. In a congenitally solitary kidney or in a congenitally functionally solitary kidney, compensatory hypertrophy is not present at birth, but develops rapidly thereafter. Measurement can be made by US or on urographic supine films. 

Compensatory hypertrophy In contralateral disease, e.g., hypo-/dys-plasia, RNP, cystic disease, nephrectomy Obstructive uropathy, neoplasm, agenesis Uncomplicated duplication Organomegaly (9)... 

De Coppi, R, A. Callegari, A. Chiav ato et al. 2007b. Anmiotic fluid and bone marrow derived mesenchymal stem cells can be converted to smooth muscle cells in the cryo-injured rat bladder and prevent compensatory hypertrophy of surviving smooth muscle cells. / Urol 177 369-376. 

The best chance of cure is offered by complete surgical resection with negative margins and restoration of biliary-enteric continuity. Resectability criteria are based on tumour extension, vascular involvement, distant metastases, the presence of coexistent liver disease or dysfunction, portal hypertension and the general condition of the patient. CCA is resectable if vascular and biliary ductal involvement is limited to one lobe of the liver, if there is no extrahepatic disease, and the patient is fit for surgery. In patients in whom the proportion of the liver to be resected is substantial, it may be useful to carry out preliminary embolisation of the appropriate branch of the portal vein, in order to induce compensatory hypertrophy of the residual lobe, which minimises the risk of postoperative liver failure. In case of doubt, surgical exploration can be performed, in order to determine the chance of resectability. 

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