Androgenic-anabolic steroids

Anabolic Agents—includes anabolic androgenic steroids such as stanozolol and other... 

Pope, H. G., and Katz, D. L. 1994. Psychiatric and medical effects of anabolic-androgenic steroid use. Archives of General Psychiatry 51 375—382. 

O Sullivan A.J., M.C. Kennedy, J.H. Casey, R.O. Day, B. Corrigan, and A.D. Wodak (2000). Anabolic androgenic steroids Medicinal assessment of present, past and potential users. Medical Journal of Australia 173 323-327. 

Anabolic-androgenic steroids (AAS) used as drugs of abuse... 

Figure 12.1 Anabolic-androgenic steroids, such as Depo -Testosterone, are often injected directly into muscle tissue. In teens, steroid use can slow or halt bone growth and damage the heart, kidneys, and liver.

Anabolic-androgenic steroids (AAS), which are analogs of the male hormone testosterone, are used among athletes and bodybuilders. AAS alter the hormonal systems of males and females, and induce many adverse effects. In addition to the sex-related changes, violent behavior and psychological dependence can also occur. The use of AAS in professional sports as well as in high school sports has aroused considerable attention. 

NIDA for Teens Facts on Drugs, Anabolic-Androgenic Steroids. http //teens.drugabuse.gov/facts/ facts sterl.asp. 

The patterns of anabolic-androgenic steroid use by sportspeople and body-builders, and their physical and psychological side-effects and dependence potential, have been very well reviewed by Brower (2002). Much of the use is by injection, and so many of this population attend needle exchanges, with the advice on reducing infection risks relevant. To increase energy, burn fat and to go through the pain barrier some will use amphetamines and opiates, either street preparations or illicit pharmaceutical supplies. In the UK the opioid nalbuphine (Nubain) has been abused in this way and, in cases where dependence becomes established, detoxification treatments can be necessary. 

Antidrug Abuse Act (1988) - This and similar state laws established criminal penalites for the distribution or possession of anabolic-androgen steroids except for the treatment of disease. Violators are subject to the penalities imposed by the Comprehensive Drug Abuse Prevention and Control Act of 1970 (see below). 

Not surprisingly, azoospermia is a classic consequence of intensive use of anabolic androgenic steroids, and it can be reflected in sterility. A well-documented case has shown that in at least some cases the condition can be reversed and fertility restored by treatment with gonadotrophins (HMG and HCG) (89). 

Copeland J, Peters R, Dillon P. Anabolic-androgenic steroid use disorders among a sample of Australian... 

Thiblin I, Petersson A. Pharmacoepidemiology of anabolic androgenic steroids a review. Fundam Clin Pharmacol 2005 19 27-44. 

Thiblin I, Runeson B, Rajs J. Anabolic androgenic steroids and suicide. Ann Clin Psychiatry 1999 11(4) 223-31. 

O Sullivan AJ, Kennedy MC, Casey JH, Day RO, Corrigan B, Wodak AD. Anabolic-androgenic steroids medical assessment of present, past and potential users. Med J Aust 2000 173(6) 323-7. 

Those who have used creatine products such as creatine monohydrate or creatine phosphate realize the effects that more creatine can provide. When anabolic/androgenic steroids (AAS) are administered they cause an increase in Phosphocreatine (CP) synthesis. Let me explain why this creatine stuff is such a cool thing. 

Many Anabolic/Androgenic Steroids (AAS) are available in an oral form. Unfortunately some are also quite toxic to the liver. Orally administered AAS are very susceptible to first pass liver deactivation unless chemical molecular structures are altered to make them harder to deactivate. When an oral AAS is swallowed it enters the stomach where it is partially broken down and passed to the small intestines. The small intestines contain a group of enzymes called CYP-450 s. These enzymes begin to break down the AAS further in an attempt to deactivate it. The AAS is then absorbed through intestinal mucosa cells and transferred to the liver portal vein for further deactivation into inactive chemicals such as etiocholanone. These chemicals are then conjugated with glucuronic acid and excreted in urine. Up to 100% of the original compound can be deactivated in this process which is known as first pass deactivation. 

Drug Class Anabolic /Androgenic steroid (Oral)... 

Drug Class Anabolic/Androgenic steroid (For injection)... 

Active-Life 2-3 days injectable/ 4-6 hours orals Drug Class Anabolic/Androgenic Steroid... 

Drug Class Anabolic/androgenic steroid (indictable)... 

---