CONTENTS Hazard Identification

Within the framework depicted in Figure 7.1, the content of risk assessment proposed by the committee is shown as comprising four analytic steps hazard identification, dose-response assessment, human exposure assessment, and a final, integrating step called risk characterization. These four terms and the activities they describe have come to be widely accepted within the risk assessment community, on... 

The conditions under which the drug is used need to be estimated as do acceptable residues linked to the level of acceptable risk to the consumer. The acceptable level of risk, which is determined in theory at the risk management stage, has already been expressed in terms of residues by the ADI under hazard characterization. Moreover, the elements considered for hazard identification, hazard characterization, and exposure assessment make it possible, for a given form of utilization of a particular substance, to establish a profile of residues in animal tissues and to associate this with a profile of consumer exposure. Comparison of this consumer profile and ADI indicates whether the mode of utilization of the substance is acceptable or not. Analysis of the different results of residue content in animal products then provides an indication of level of residues in one or several animal tissues, making it possible to differentiate between veterinary drug applications that do or do not permit compliance with the ADI. 

Hazard identification of the contents of in-plant bulk storage tanks, warehouses, etc, may be achieved by a system developed by the NFPA (48). The system makes use of three diamond-shaped areas, which are marked with numbers 0, 1, 2, 3, or 4 indicating increasing hazards of toxicity, flammability,... 

CFR1910.1200 41CFR101-42.202(a) through (c) 4.1.3 Identification and Documentation of Hazardous Materials - Actual or potential hazards associated with an excess hazardous material shall be documented with a Material Safety Data Sheet (MSDS) supplied by the manufacturer, distributor or importer. If an MSDS is not available, a Hazardous Materials Identification System (HMIS) record from the automated Department of Defense database is acceptable. If an MSDS or HMIS record is not available, a hazard identification document prepared by the owning DOE organization that meets the MSDS content requirements for hazardous chemicals set forth in the OSHA Hazard Communication Standard (29CFR1910.1200) shall be used. 

HCF procedure development maintains consistency by follow/ing the TA-V Nuclear Facilities Conduct of Operations Manual (SNL 1998a) and the SNL ES H Manual (SNL 1998b). These documents describe procedure format and content, including Purpose, Scope, Ownership, Responsibilities, Definitions and Acronyms, Hazard Identification, Equipment and Materials, Format, Review and Approval Authority, and Document Control. Use of this format complies with DOE Order 5480.19, Conduct of Operations, Chapter 16 (DOE 1990). TA-V Standard Operating Procedures are written for tasks specifically identified in the Technical Safely Requirements (TSR) or as required by other directives or the SNL ES H manual to address special hazards. TA-V document types and hierarchy is described in TA-V Nuclear Facilities Conduct of Operations Manual (SNL 1998a) Chapter 16. 

Identifying and Evaluating Hazards in Research Laboratories , Hazards Identification and Evaluation Task Force of the American Chemical Society Committee on Chemical Safety, 2013, http //www.acs.org/ content/dam/acsorg/about/governance/committees/chemicalsafety/ide ntifying-and-evaluating-hazards-in-research-laboratories-draft.pdf, (accessed Jan 2015). 

SDSs used to be Material Data Safety Sheets (MSDSs) and the implementation of the GHS requires this change. Most of the content of this section refers equally well to SDSs and MSDSs. Historical references are more about MSDSs and current comments are about SDSs. You need to be comfortable in reading both kinds of documents, but they are so similar in nature except SDSs have information about GHS hazard identification that you will not find in MSDSs. We will refer mostly to SDSs in this section, with a few exceptions. 

Selected entries from Methods in Enzymology [vol, page(s)] Types of organophosphorus inhibitors, 11,686-688 toxicity hazards, 11,688 purity and analysis, 11,688 solutions of organophosphorus compounds, 11,689 estimation of specific radioactivity of organophosphorus compounds, 11,689-690 method for estimating phosphorus content, 11,691 reactions with enzymes, 11,691 -701 [rate constants, 11,692 phosphorylation of chymotrypsin, 11, 694-696 identification of phosphoryl and phosphonyl peptides,... 

The system is used by the DOT for shipping hazardous materials however, when the hazardous material reaches its destination and is removed from the shippmg container, this identification is lost. The laboratory must then label each individual container. Usually the information necessary to classify the contents of the container appropriately is contained on the shipping label and should be noted. Important first-aid information is also usually provided on this label. 

Pari 1, Making a Plan examining documentation, line identification and contents, isolation, hazards, and what if approach. Pari 2, Shutdown and Isolation steps to isolate work area, replace control valve, and reopen line. 

In the absence of regulation, companies need to consider the extent to which label identification of contents would reveal valuable commercial secrets. Protection of these secrets involves different considerations depending upon whether hazardous labelling will be used within the trade secret owners workplace or outside of it. Since employees can be bound to keep such informa-... 

Colours play an essential safety role in giving information for use in tbe prevention of accidents, for warning of health hazards, to identify contents of gas cylinders, pipeline and services, the identification and safe use of cables and components in electronic and electrical installations as well as the correct use of fire-fighting equipment. 

Persons who supervise hazard control operations related to asbestos, tremolite, anthophyllite, and actinolite must be trained in engineering controls and in abatement, the contents of this standard, and identification and removal procedures. 

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