Cisplatin/methotrexate/vinblastine

Doxorubin Etoposide Methotrexate Mitoxantrone Cisplatin Vincristine Vinblastine Iiinotecan ... [Pg.45]

Morrell LE, Lee YJ, Hurley J, et al. A Phase II trial of neoadjuvant methotrexate, vinblastine, doxorubicin, and cisplatin in the treatment of patients with locally advanced breast carcinoma. Cancer 1998 82 503-511. [Pg.249]

Harker WG, Meyers FJ, Freiha FS, et al. Cisplatin, methotrexate, and vinblastine (CMV) an effective chemotherapy regimen for metastatic transitional cell carcinoma of the urinary tract a Northern California Oncology Group study. J Clin Oncol 1985 3 1463-1470. [Pg.300]

Sternberg CN, Yagoda A, Scher HI, et al. Methotrexate, vinblastine, doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium efficacy and patterns of response and relapse. Cancer 1989 64 2448-2458. [Pg.300]

Loehrer PJ, Einhom LH, Elson PJ, et al. A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma a cooperative group study. J Clin Oncol 1992 7 1066-1073. [Pg.300]

Loehrer PJ, Elson P, Dreicer R, et al. Escalated dosages of methotrexate, vinblastine, doxorubicin, and cisplatin plus recombinant human granulocyte colony-stimulating factor in advanced urothelial carcinoma an Eastern Cooperative Oncology Group trial. J Clin Oncol 1994 12 483-488. [Pg.300]

Roth BJ, Bajorin DF. Advanced bladder cancer the need to identify new agents in the post-M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) world. J Urol 1995 153 894-900. [Pg.300]

Medical Research Council Advanced Bladder Cancer Working Party. Neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer a randomised controlled trial. Lancet 1999 354 533-540. [Pg.301]

Conti JA, Scher HI. Acute arterial thrombosis after escalated-dose methotrexate, vinblastine, doxorubicin, and cisplatin chemotherapy with recombinant granulocyte colony-stimulating factor. A possible new recombinant granulocyte colony-stimulating factor toxicity. Cancer 1992 70(ll) 2699-702. [Pg.1550]

Forty patients with lung cancer, treated with a combination of cisplatin, mitomycin, vinblastine, doxorubicin, cyclosphosphamide, and methotrexate, had a significant post-treatment increase in fibrinopeptide A and a fall in fibrinolytic activity, reflected by a fall in functional tissue activator this appeared to be cumulative, depending on the extent of drug exposure (184). [Pg.2859]

Intravenous Chemotherapy. The most effective chemotherapeutic agent for bladder carcinoma is cisplatin with objective responses ranging from 26% to 56%, with complete responses seen in 0%-14%. In a study of 121 patients, MVAC (methotrexate, vinblastine, doxorubicin [Adriamycin] and cisplatin) demonstrated an overall response rate of 72% one half of the responses being complete (Sternberg et al. 1989). The median survival was 13 months. CISCA (cisplatin, doxorubicin, and cyclophosphamide) was compared to MVAC MVAC proved to be superior with a difference in median survival of 82 versus 40 weeks (Logothetis... [Pg.208]

B = bleomycin, C = chlorambucil, CT = chemotherapy, DFS = disease-free survival, Ep = epirubicin, F = fluorouracil, I = ifosfamide, M = mitomycin C, Mtx = methotrexate, O = vincristine, OS = overall survival, P = cisplatin, RT = radiation therapy, V = vinblastine. [Pg.308]

Carcinoma of lung Cisplatin plus taxane Methotrexate, vincristine, vinblastine, doxorubicin, mitomycin C... [Pg.1311]

Carcinoma of testis Combination chemotherapy cisplatin, bleomycin, and etoposide Methotrexate, dactinomycin, plicamycin, vinblastine, doxorubicin, cyclophosphamide, etoposide, ifosfamide plus mesna1... [Pg.1311]

Choriocarcinoma (trophoblastic neoplasms) Methotrexate alone or etoposide and cisplatin Vinblastine, mercaptopurine, chlorambucil, doxorubicin... [Pg.1312]

Chlorambucil, cisplatin, daunorubicin, doxorubicin, etoposide, flnoro uracil, hydroxyurea, methotrexate, mitoxantrone, tamoxifen, vinblastine, vincristine. [Pg.240]

Endometrial Ewing s sarcomao" Gastric Head and neck,squamous cell Islet cell (pancreas) Kaposi s sarcoma Doxorubicin cisplatin + cyclophosphamide CAV Cyclophosphamide (or Ifosfamide) + doxorubicin (Adriamycin) + vincristine CF epirubidri + cisplatin 5-fluorouraci1 Cisplatin + S-fluorouracil Methotrexate Screptozotocin + S-fluorouracil Etoposide or interferon affa or vinblastine ABV doxorubicin (Adriamycin) + bteomycin + vincristine or vinblastine... [Pg.607]

Clinically important, potentially hazardous interactions with altretamine, amikacin, aminoglycosides, antineoplastics, bleomycin, busulfan, carboplatin, carmustine, chlorambucil, cisplatin, corticosteroids, cyclophosphamide, cytarabine, dacarbazine, dactinomycin, daunorubicin, docetaxel, doxorubicin, estramustine, etoposide, fludarabine, fluorouracil, gemcitabine, gentamicin, hydroxyurea, idarubicin, ifosfamide, indomethacin, kanamycin, levamisole, lomustine, mechlorethamine, melphalan, mercaptopurine, methotrexate, mitomycin, mitotane, mitoxantrone, neomycin, pentostatin, plicamycin, procarbazine, streptomycin, streptozocin, thioguanine, thiotepa, tobramycin, tretinoin, uracil, vinblastine, vincristine, vinorelbine... [Pg.13]

ABCC2 MRP2 Cisplatin, doxorubicin, etoposide, irinotecan, methotrexate, SN-38 (metabolite of irinotecan), vincristine, vinblastine... [Pg.124]

In addition to the drugs mentioned above (doxorubicin, 5-fluoruracil, methotrexate, and cyclophosphamide), researchers have found other chemotherapy compounds to be common in studies that looked at problems with language, memory, and other cognitive abilities. These drugs include cisplatin, vincristine, etoposide, vinblastine, and steroids such as dexamethasone and prednisone. Their relative risks associated with later cognitive impairment, however, have not been well established. [Pg.16]

Some cancer chemotherapeutic drugs are carcinogenic and/or mutagenic. They are widely used in hospital and laboratories, and there is a widespread demand for methods for their safe disposal and for surface decontamination, a field completely neglected. Research was therefore initiated on a number of these compounds doxorubicin, daunorubicin, methotrexate, dichlorom-ethotrexate, cyclophosphamide, ifosfamide, vincristine sulfate, vinblastine sulfate, 6-thioguanine, 6-mer-captopurine, cisplatin, lomustine, chlorozotocin, streptozotocin, carmustine, semustine, PCNU and melphalan. [Pg.64]

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