Chemotherapeutic effect

Synthetic Pteridines with Chemotherapeutic Effects Folic Acid and Related Derivatives... 

Resistance of neoplastic ceUs to the chemotherapeutic effect of 6-mercaptopurine would most likely involve loss or inactivation of a gene encoding... 

Some Japanese researchers at the Kyoto University of Medicines have developed a new method for removal of large stones (mineral deposits) in kidney and bladder by using micro-explosive charges without any surgery [118-120]. Recently, applications of underwater shock waves have been extended to various clinical therapies for example, in orthopedic surgery for bone formation [121, 122], in cancer therapy, for enhancement of chemotherapeutic effects [123] and in drug delivery [124, 125]. 

Brindley, P.J. and Sher, A. (1 987) The chemotherapeutic effect of praziquantel against Schistosoma mansoni is dependent on host antibody response. The Journal of Immunology 1 39, 215-220. 

Conklin, K.A., Dietary antioxidants during cancer chemotherapy impact on chemotherapeutic effectiveness and development of side effects, Nutr. Cancer, 37(1), 1-18, 2000. 

Jusko, W., Pharmacodynamics of chemotherapeutic effects Dose-time-response relationships for phase-nonspecific agents, Journal of Pharmaceutical Sciences, Vol. 60, No. 6, 1971, pp. 892-895. 

Most drugs produce a reversible pharmacological response. However, some antibiotics, irreversible enzyme inhibitors, and anticancer agents incorporate irreversibly or covalently into a cell s metabolic pathway. This results in an irreversible effect—cell death. Complex kinetic models are used to explain the relationship of dose-chemotherapeutic effects for some drugs, such as methotrexate, cyclophosphamide, and arabinosylcytosine.f ... 

Logan. R.P. (1996) The chemotherapeutic effects of H /K inhibitors on Helicobacter pylori infection. Pharmacol. Then, 89.79-83. 

S. Liao/U. of Chicago Determine if green tea extracts, a complex herbal known as PCSPES, and extracts of individual PCSPES components affect the chemotherapeutic effect of growth of a drug used for prostate cancer In vitro... 

Jusko WJ. 1971. Pharmacodynamics of chemotherapeutic effects dose-time response relationships for phase-non-specific agents . J. Pharm. Sci. 60 892. 

E. D. Lobo and J. P. Balthasar, Pharmacodynamic modeling of chemotherapeutic effects application of a transit compartment model to characterize methotrexate effects in vitro. Am Assoc Pharm Sci Pharm Sci 4(4) 42 (2002). 

One in every 1,000 people in the United States currently receives lithium, as Li2C03, for the treatment and prophylaxis of manic-depressive behavior. Doses of 250 mg to 2 g per day are administered in order to maintain a 0.5 to 2.0 mM concentration window, outside of which the drug is either toxic or ineffective. The detailed molecular mechanism by which Li ion brings about its remarkable chemotherapeutic effects is largely unknown, but there are various theories. One theory proposes that lithium binds to inositol phosphates, inhibiting their breakdown to inositol, and so reducing inositol-containing phospholipids. A consequence of this chain of events would be disruption of the neurotransmis-... 

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